Skip to main content

Articles

3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

Page 44 of 79

  1. Interleukins and cytokines play an important role in the pathogenesis of many solid cancers. Several single nucleotide polymorphisms (SNPs) identified in cytokine genes are thought to influence the expression ...

    Authors: SP Balasubramanian, IAF Azmy, SE Higham, AG Wilson, SS Cross, A Cox, NJ Brown and MW Reed
    Citation: BMC Cancer 2006 6:188
    Content type: Research article Published on:

  2. Palliative care, as a relatively young field within medicine, has increasingly used original research to validate and standardize its practice. In particular, palliative care has been incorporated into oncolog...

    Authors: Corbin Eule, Nizar Bhulani, Elizabeth Paulk, Ramona Rhodes and Muhammad Shaalan Beg
    Citation: BMC Cancer 2018 18:1281
    Content type: Research article Published on:

  3. Multiple myeloma is a heterogeneous disorder and the intratumor genetic heterogeneity contributes to emergency of drug resistance. Dexamethasone has been used clinically for decades for MM. Nevertheless, their...

    Authors: Yuyue Ren, Yijun Liu, Wanting He, Weiwei Zhao, Jiaqi Pan, Haiyan Gao, Yuying Li, Ying Zhang and Wei Wang
    Citation: BMC Cancer 2023 23:630
    Content type: Research Published on:

  4. Ankyrin repeat domain 49 (ANKRD49) has been found to be highly expressed in multiple cancer including lung adenocarcinoma (LUAD) and lung squamous carcinoma (LUSC). However, the function of ANKRD49 in the path...

    Authors: Jia Sun, Jin-rui Hu, Chao-feng Liu, Yuan Li, Wei Wang, Rong Fu, Min Guo, Hai-long Wang and Min Pang
    Citation: BMC Cancer 2023 23:1108
    Content type: Research Published on:

  5. Mitogen/extracellular signal-regulated kinase kinase-5 (MEK5) has been confirmed to play a pivotal role in tumor carcinogenesis and progression. However, few studies have investigated the role of MEK5 in color...

    Authors: Dechang Diao, Lei Wang, Jin Wan, Zhiqiang Chen, Junsheng Peng, Huanliang Liu, Xinlin Chen, Wei Wang and Liaonan Zou
    Citation: BMC Cancer 2016 16:302
    Content type: Research article Published on:

  6. In this study, we retrospectively investigated the prognostic role of pre-treatment neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in esophageal squamous cell carcinoma patients (E...

    Authors: Qirong Man, Peishun Li, Jing Fan, Sen Yang, Chao Xing, Yunling Bai, Miaomiao Hu, Baohu wang and Kaixian Zhang
    Citation: BMC Cancer 2024 24:464
    Content type: Research Published on:

  7. Quality of cancer care (QoCC) has become an important item for providers, regulators and purchasers of care worldwide. Aim of this study is to present the results of some evidence-based quality indicators (QI)...

    Authors: Laura Ortelli, Alessandra Spitale, Luca Mazzucchelli and Andrea Bordoni
    Citation: BMC Cancer 2018 18:733
    Content type: Research article Published on:

  8. Low-molecular-weight heparin (LMWH) is recommended and commonly used for extended treatment of cancer-associated thrombosis (CAT), but its superiority over warfarin has been demonstrated in only one randomised...

    Authors: Agnes YY Lee, Rupert Bauersachs, Mette S Janas, Mikala F Jarner, Pieter W Kamphuisen, Guy Meyer and Alok A Khorana
    Citation: BMC Cancer 2013 13:284
    Content type: Study protocol Published on:

  10. This study examines prognostic value of preoperative serum bilirubin, including unconjugated bilirubin (UCB), conjugated bilirubin (CB), and total bilirubin (TB), in esophageal squamous cell carcinoma (ESCC) p...

    Authors: Xiancong Huang, Yang Chen, Huan Yang, Ruting Wang and Zhongjian Chen
    Citation: BMC Cancer 2023 23:706
    Content type: Research Published on:

  11. Urothelial carcinoma (UC) is among the most prevalent malignancies. The muscle-invasive bladder cancer (MIBC) shows an invasive feature and has poor prognosis, while the non-muscle invasive bladder cancer (NMI...

    Authors: Qiongqiong Lin, Lu Pei, Zhiguang Zhao, Xiaoping Zhuang and Haide Qin
    Citation: BMC Cancer 2022 22:817
    Content type: Research Published on:

  12. Cell-surface glycoproteins play critical roles in cell-to-cell recognition, signal transduction and regulation, thus being crucial in cell proliferation and cancer etiogenesis and development. DPP IV and NEP a...

    Authors: Adolfo Varona, Lorena Blanco, Itxaro Perez, Javier Gil, Jon Irazusta, José I López, M Luz Candenas, Francisco M Pinto and Gorka Larrinaga
    Citation: BMC Cancer 2010 10:193
    Content type: Research article Published on:

  13. The novel breast cancer metastasis modulator gene signal-induced proliferation-associated 1 (Sipa1) underlies the breast cancer metastasis efficiency modifier locus Mtes 1 and has been shown to influence mammary ...

    Authors: Szu-Min Hsieh, Robert A Smith, Nicholas A Lintell, Kent W Hunter and Lyn R Griffiths
    Citation: BMC Cancer 2009 9:331
    Content type: Research article Published on:

  14. Among gynaecological malignancies, endometrial cancer (EC) is the most prevalent type of uterine cancer affecting women. This study explored the proteomic profiles of plasma samples obtained from EC patients, ...

    Authors: Khalid Akkour, Ibrahim O Alanazi, Assim A Alfadda, Afshan Masood, Hani Alhalal, Salini Scaria Joy, Ali Bassi, Eman Alshehri, Moudi A Alwehaibi, Maria Arafah and Hicham Benabdelkamel
    Citation: BMC Cancer 2024 24:752
    Content type: Research Published on:

  15. Over the last decades, the therapeutic armamentarium of metastatic renal cell carcinoma (mRCC) has been revolutionized by the advent of tyrosin-kinase inhibitors (TKI), immune-checkpoint inhibitors (ICI), and ...

    Authors: Mimma Rizzo, Gaetano Pezzicoli, Valentina Tibollo, Andrea Premoli and Silvana Quaglini
    Citation: BMC Cancer 2024 24:804
    Content type: Research Published on:

  16. The Rearranged during Transfection (RET) protein is overexpressed in a subset of Estrogen Receptor (ER) positive breast cancer, with both signalling pathways functionally interacting. This cross-talk plays a p...

    Authors: Robert Mechera, Savas D. Soysal, Salvatore Piscuoglio, Charlotte K. Y. Ng, Jasmin Zeindler, Edin Mujagic, Silvio Däster, Philippe Glauser, Henry Hoffmann, Ergin Kilic, Raoul A. Droeser, Walter P. Weber and Simone Muenst
    Citation: BMC Cancer 2019 19:41
    Content type: Research article Published on:

  17. Hyponatraemia is a common finding in patients with cancer, and has been shown to be associated with poor prognosis in different settings. We have analysed the impact of severe hyponatraemia in patients with ca...

    Authors: Kirsty Balachandran, Alicia Okines, Ranga Gunapala, Daniel Morganstein and Sanjay Popat
    Citation: BMC Cancer 2015 15:163
    Content type: Research article Published on:

  18. Most of the blood tests aiming for breast cancer screening rely on quantification of a single or few biomarkers. The aim of this study was to evaluate the feasibility of detecting breast cancer by analyzing th...

    Authors: Udi Zelig, Eyal Barlev, Omri Bar, Itai Gross, Felix Flomen, Shaul Mordechai, Joseph Kapelushnik, Ilana Nathan, Hanoch Kashtan, Nir Wasserberg and Osnat Madhala-Givon
    Citation: BMC Cancer 2015 15:408
    Content type: Research article Published on:

  19. Programmed death-1 (PD-1) and its ligand (PD-L1) inhibitors have been reported in several clinical trials for gastric cancer and gastroesophageal junction cancer (GC/GEJC). We presently carried out a meta anal...

    Authors: Gengwei Huo, Wenjie Liu and Peng Chen
    Citation: BMC Cancer 2023 23:143
    Content type: Research Published on:

  20. Metabolomics has a great potential in the development of new biomarkers in cancer and it has experiment recent technical advances.

    Authors: Lucía Trilla-Fuertes, Angelo Gámez-Pozo, Elena López-Camacho, Guillermo Prado-Vázquez, Andrea Zapater-Moros, Rocío López-Vacas, Jorge M. Arevalillo, Mariana Díaz-Almirón, Hilario Navarro, Paloma Maín, Enrique Espinosa, Pilar Zamora and Juan Ángel Fresno Vara
    Citation: BMC Cancer 2020 20:307
    Content type: Research article Published on:

  21. The aim of the present study was to evaluate the predictive value of a novel quantitative measure for the spatial heterogeneity of FDG uptake, the asphericity (ASP) in patients with non-small cell lung cancer ...

    Authors: Ivayla Apostolova, Julian Rogasch, Ralph Buchert, Heinz Wertzel, H Jost Achenbach, Jens Schreiber, Sandra Riedel, Christian Furth, Alexandr Lougovski, Georg Schramm, Frank Hofheinz, Holger Amthauer and Ingo G Steffen
    Citation: BMC Cancer 2014 14:896
    Content type: Research article Published on:

  22. Although immune-checkpoint inhibitors (ICI) are overall promissory for cancer treatment, they entail, in some cases, an undesired side-effect called hyperprogressive-cancer disease (HPD) associated with accele...

    Authors: Daniela R. Montagna, Alejandra Duarte, Paula Chiarella, Bárbara Rearte, Oscar D. Bustuoabad, Mónica Vermeulen and Raúl A. Ruggiero
    Citation: BMC Cancer 2022 22:845
    Content type: Research Published on:

  23. Emerging evidence has identified miR-138 as a tumor suppressor that can suppress the proliferation of various cancers. Meanwhile, the cause of abnormal miR-138 expression in cervical cancer remains uncertain. ...

    Authors: Rui Chen, Qiyu Gan, Shuting Zhao, Dongrui Zhang, Shunli Wang, Lili Yao, Min Yuan and Jingxin Cheng
    Citation: BMC Cancer 2022 22:488
    Content type: Research Published on:

  24. Biomarkers allowing the characterization of malignancy and therapy response of oral squamous cell carcinomas (OSCC) or other types of carcinomas are still outstanding. The biochemical suicide molecule endonucl...

    Authors: Martin Grimm, Steffen Schmitt, Peter Teriete, Thorsten Biegner, Arnulf Stenzl, Jörg Hennenlotter, Hans-Joachim Muhs, Adelheid Munz, Tatjana Nadtotschi, Klemens König, Jörg Sänger, Oliver Feyen, Heiko Hofmann, Siegmar Reinert and Johannes F Coy
    Citation: BMC Cancer 2013 13:569
    Content type: Research article Published on:

  25. Anemia has been a known prognostic factor in metastatic hormone-sensitive prostate cancer (mHSPC). We therefore examined the effect of anemia on the efficacy of upfront abiraterone acetate (ABI) in patients wi...

    Authors: Teppei Okamoto, Daisuke Noro, Shingo Hatakeyama, Shintaro Narita, Koji Mitsuzuka, Toshihiko Sakurai, Sadafumi Kawamura, Senji Hoshi, Jiro Shimoda, Toshikazu Tanaka, Toshiaki Kawaguchi, Shigeto Ishidoya, Akihiro Ito, Norihiko Tsuchiya, Tomonori Habuchi and Chikara Ohyama
    Citation: BMC Cancer 2021 21:605
    Content type: Research article Published on:

  26. A major impediment in the treatment of ovarian cancer is the relapse of chemotherapy-resistant tumors, which occurs in approximately 25% of patients. A better understanding of the biological mechanisms underly...

    Authors: Jihoon Choi, Danai G. Topouza, Anastasiya Tarnouskaya, Sean Nesdoly, Madhuri Koti and Qing Ling Duan
    Citation: BMC Cancer 2020 20:413
    Content type: Research article Published on:

  27. Aldehyde dehydrogenase 1 (ALDH1) is widely used as a specific cancer stem cell marker in a variety of cancers, and may become a promising target for cancer therapy. However, the role of its expression in tumor...

    Authors: Ruixia Huang, Xiaoran Li, Ruth Holm, Claes G. Trope, Jahn M. Nesland and Zhenhe Suo
    Citation: BMC Cancer 2015 15:502
    Content type: Research article Published on:

  28. Yes-associated protein (YAP) plays a crucial role in tumour development and it is the main effector of the Hippo signalling pathway. However, the mechanism underlying YAP downregulation in laryngeal cancer is ...

    Authors: Xiaomin Tang, Yuxuan Sun, Ganglun Wan, Jiaqiang Sun, Jingwu Sun and Chunchen Pan
    Citation: BMC Cancer 2019 19:654
    Content type: Research article Published on:

  31. Research and cancer care are closely intertwined; however, it is not clear whether physicians and nurses believe that clinical trials offer the best treatment for patients and, if so, whether this belief is ju...

    Authors: Zandra Engelbak Nielsen, Stefan Eriksson, Laurine Bente Schram Harsløf, Suzanne Petri, Gert Helgesson, Margrete Mangset and Tove E. Godskesen
    Citation: BMC Cancer 2020 20:401
    Content type: Research article Published on:

  32. The transcription factor hypoxia inducible factor (HIF) -1 drives tumor growth and metastasis and is associated with poor prognosis in breast cancer. Ascorbate can moderate HIF-1 activity in vitro and is assoc...

    Authors: Elizabeth J. Campbell, Gabi U. Dachs, Helen R. Morrin, Valerie C. Davey, Bridget A. Robinson and Margreet C. M. Vissers
    Citation: BMC Cancer 2019 19:307
    Content type: Research article Published on:

  33. Breast cancer is the most common cancer type in female. As microRNAs play vital role in breast cancer, this study aimed to explore the molecular mechanism and clinical value of miR-21 in breast cancer.

    Authors: Hui Wang, Zheqiong Tan, Hui Hu, Hongzhou Liu, Tangwei Wu, Chao Zheng, Xiuling Wang, Zhenzhao Luo, Jing Wang, Shuiyi Liu, Zhongxin Lu and Jiancheng Tu
    Citation: BMC Cancer 2019 19:738
    Content type: Research article Published on:

  34. Giant breast malignant phyllodes tumor or sarcoma (GBPS) are rare entities with diameter larger than 10 cm and variously histological pleomorphisms. This disease poses a significant threat to the quality of li...

    Authors: Naiquan Liu, Ye Kang, Ningxin Qu, Chenhui Kong and Ye Han
    Citation: BMC Cancer 2023 23:801
    Content type: Research Published on:

  35. MicroRNA (miRNA) signatures are not only found in cancer tissue but also in blood of cancer patients. Specifically, miRNA detection in blood offers the prospect of a non-invasive analysis tool.

    Authors: Petra Leidinger, Andreas Keller, Anne Borries, Jörg Reichrath, Knuth Rass, Sven U Jager, Hans-Peter Lenhof and Eckart Meese
    Citation: BMC Cancer 2010 10:262
    Content type: Research article Published on:

  36. The molecular prognostic biomarkers of clear cell renal cell carcinoma (ccRCC) are still unknown. We aimed at researching the candidate biomarkers and potential therapeutic targets of ccRCC.

    Authors: Jing Quan, Yuchen Bai, Yunbei Yang, Er Lei Han, Hong Bai, Qi Zhang and Dahong Zhang
    Citation: BMC Cancer 2021 21:814
    Content type: Research Published on:

  37. Programmed cell death ligand 1 (PD-L1) is an important immune-inhibitory protein expressed on cancer cells to mediate cancer escape through interaction with PD-1 expressed on activated T lymphocytes (T cells)....

    Authors: Mingshui Chen, Aditi Sharma, Yanling Lin, Yanheng Wu, Qi He, Yushu Gu, Zhi Ping Xu, Michael Monteiro and Wenyi Gu
    Citation: BMC Cancer 2019 19:153
    Content type: Research article Published on:

  38. Penile cancer is a rare disease in demand for new therapeutic options. Frequently used combination chemotherapy with 5 fluorouracil (5-FU) and cisplatin (CDDP) in patients with metastatic penile cancer mostly ...

    Authors: Ria Winkelmann, Katrin Bankov, Claudia Döring, Jaroslav Cinatl, Sebastian Grothe, Florian Rothweiler, Martin Michaelis, Christina Schmitt, Peter J. Wild, Melanie Demes, Jindrich Cinatl Jr. and Stefan Vallo
    Citation: BMC Cancer 2022 22:1352
    Content type: Research Published on:

  39. Genomic profiles of specific gene sets have been established to guide personalized treatment and prognosis for patients with breast cancer (BC). However, epigenomic information has not yet been applied in a cl...

    Authors: Yang-Hong Dai, Ying-Fu Wang, Po-Chien Shen, Cheng-Hsiang Lo, Jen-Fu Yang, Chun-Shu Lin, Hsing-Lung Chao and Wen-Yen Huang
    Citation: BMC Cancer 2021 21:945
    Content type: Research article Published on:

  40. Renal cell cancer (RCC) is one of the most frequent primary sites for metastatic pancreatic tumors although metastatic tumors are rare among pancreatic malignant tumors. The purpose of this study is to disclos...

    Authors: Takeshi Yuasa, Naoko Inoshita, Akio Saiura, Shinya Yamamoto, Shinji Urakami, Hitoshi Masuda, Yasuhisa Fujii, Iwao Fukui, Yuichi Ishikawa and Junji Yonese
    Citation: BMC Cancer 2015 15:46
    Content type: Research article Published on:

  41. While colorectal cancer (CRC) patients with localized disease have a favorable prognosis, the five-year-survival rate in patients with distant spread is still below 15%. Hence, a detailed understanding of the ...

    Authors: Sarah Weber, Sebastian E. Koschade, Christopher M. Hoffmann, Taronish D. Dubash, Klara M. Giessler, Sebastian M. Dieter, Friederike Herbst, Hanno Glimm and Claudia R. Ball
    Citation: BMC Cancer 2019 19:1181
    Content type: Research article Published on:

  42. Since body mass index (BMI) is a convincing risk factor for breast cancer, it is speculated to be associated with lymph node metastasis. However, epidemiological studies are inconclusive. Therefore, this study...

    Authors: Junyi Wang, Yaning Cai, Fangfang Yu, Zhiguang Ping and Li Liu
    Citation: BMC Cancer 2020 20:601
    Content type: Research article Published on:

  43. The Int7G24A variant of transforming growth factor-beta receptor type I (TGFBR1) has been shown to increase the risk for kidney, ovarian, bladder, lung and breast cancers. Its role in colorectal cancer (CRC) has ...

    Authors: Adela Castillejo, Trinidad Mata-Balaguer, Carla Guarinos, María-Isabel Castillejo, Ana Martínez-Cantó, Víctor-Manuel Barberá, Paola Montenegro, Enrique Ochoa, Rafael Lázaro, Carmen Guillén-Ponce, Alfredo Carrato and José-Luís Soto
    Citation: BMC Cancer 2009 9:406
    Content type: Research article Published on:

  44. Studies have shown that the absolute lymphocyte count (ALC) and the neutrophil-to-lymphocyte ratio (NLR) are related to the outcomes in patients with breast cancer receiving specific chemotherapies. However, t...

    Authors: Meng-Xia Su, Hsiang-Wen Lin, Hanh T. H. Nguyen, Tien-Chao Lin, Chih-Jung Chen, Hwei-Chung Wang, Chen-Teng Wu, Yao-Chung Wu, Geng-Yan He, Liang-Chih Liu and Chih-Hao Huang
    Citation: BMC Cancer 2024 24:195
    Content type: Research Published on:

  46. Dysregulation of inhibitor of differentiation/DNA binding (ID) genes is linked to cancer growth, angiogenesis, invasiveness, metastasis and patient survival. Nevertheless, few investigations have systematically d...

    Authors: Qi Zhao, Yun Wang, Di Yu, Jia-Yan Leng, Yangjing Zhao, Mingqiang Chu, Zijun Xu, Hao Ding, Jingdong Zhou and Tingjuan Zhang
    Citation: BMC Cancer 2022 22:1229
    Content type: Research Published on:

  47. Breast cancer is the second most lethal cancer in women. Understanding biological mechanisms that cause progression of this disease could yield new targets for prevention and treatment. Recent experimental stu...

    Authors: Qi Cao, Jerome Hersl, Hongloan La, Mark Smith, Jason Jenkins, Olga Goloubeva, Vasken Dilsizian, Katherine Tkaczuk, Wengen Chen and Laundette Jones
    Citation: BMC Cancer 2014 14:126
    Content type: Research article Published on:

  48. The incidence of early-onset colorectal cancer (EOCRC, diagnosed in patients under the age of 50 years) has been increasing around the world. Here, we aimed to systematically identify distinctive features of E...

    Authors: Hongwei Liu, Huifang Xu, Yin Liu, Yuqian Zhao, Xi Zhang, Yanqin Yu, Lingbin Du, Yunyong Liu, Wenjun Wang, Helu Cao, Li Ma, Juanxiu Huang, Ji Cao, Li Li, Yanping Fan, Xiaofen Gu…
    Citation: BMC Cancer 2024 24:503
    Content type: Research Published on:

  49. Nc886 is a 102 bp non-coding RNA transcript initially classified as a microRNA precursor (Pre-miR-886), later as a divergent homologue of the vault RNAs (vtRNA 2–1) and more recently as a novel type of RNA (nc...

    Authors: Rafael Sebastián Fort, Cecilia Mathó, Murilo Vieira Geraldo, María Carolina Ottati, Alex Shimura Yamashita, Kelly Cristina Saito, Katia Ramos Moreira Leite, Manuel Méndez, Noemí Maedo, Laura Méndez, Beatriz Garat, Edna Teruko Kimura, José Roberto Sotelo-Silveira and María Ana Duhagon
    Citation: BMC Cancer 2018 18:127
    Content type: Research article Published on:

  50. In ovarian cancer, massive intraperitoneal dissemination is due to exfoliated tumor cells in ascites. Tumor-initiating cells (TICs or cancer stem cells) and cells showing epithelial-mesenchymal-transition (EMT...

    Authors: My Wintzell, Elisabet Hjerpe, Elisabeth Åvall Lundqvist and Maria Shoshan
    Citation: BMC Cancer 2012 12:359
    Content type: Research article Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Follow

BMC Cancer

ISSN: 1471-2407

Contact us