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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. We recently showed that LOH proximal to M6P/IGF2R locus (D6S1581) in primary ovarian tumors is predictive for the presence of disseminated tumor cells (DTC) in the bone marrow (BM). For therapy-monitoring, it wou...

    Authors: Jan Dominik Kuhlmann, Heidi Schwarzenbach, Pauline Wimberger, Micaela Poetsch, Rainer Kimmig and Sabine Kasimir-Bauer
    Citation: BMC Cancer 2012 12:325
    Content type: Research article Published on:

  2. The Wnt receptors ROR1 and ROR2 are generating increased interest as cancer therapeutic targets but remain understudied in pancreatic ductal adenocarcinoma (PDAC). Compared to canonical Wnt/ β-catenin signalli...

    Authors: Dongli Liu, George Sharbeen, Phoebe Phillips and Caroline E. Ford
    Citation: BMC Cancer 2021 21:1199
    Content type: Research Published on:

  3. The copper metabolism MURR1 domain (COMMD) protein family involved in tumor development and progression in several types of human cancer, but little is known about the function of COMMD proteins in hepatocellu...

    Authors: Xiaobo Wang, Shujiao He, Xin Zheng, Shanzhou Huang, Honghui Chen, Huadi Chen, Weixin Luo, Zhiyong Guo, Xiaoshun He and Qiang Zhao
    Citation: BMC Cancer 2021 21:1001
    Content type: Research article Published on:

  4. LncRNA N6-methylandenosine (m6A) modification has been shown to be associated with the constitution of the tumor microenvironment (TME) and tumorigenesis. It’s essential to understand the mechanisms of lncRNA ...

    Authors: Bo Chen, Zhan Yang, Zhichao Lang, Qiqi Tao, Rongrong Zhang, Yating Zhan, Xuantong Xu, Kai Zhu, Jianjian Zheng, Zhengping Yu and Suhui Yu
    Citation: BMC Cancer 2022 22:867
    Content type: Research Published on:

  5. Traditional prognostic indicators of breast cancer, i.e. lymph node diffusion, tumor size, grading and estrogen receptor expression, are inadequate predictors of metastatic relapse. Thus, additional prognostic...

    Authors: Emanuela Guerra, Alessia Cimadamore, Pasquale Simeone, Giovanna Vacca, Rossano Lattanzio, Gerardo Botti, Valentina Gatta, Marco D’Aurora, Barbara Simionati, Mauro Piantelli and Saverio Alberti
    Citation: BMC Cancer 2016 16:649
    Content type: Research article Published on:

  6. Recent studies have extensively investigated the role of miRNAs in colorectal cancer (CRC), and several associations have been reported. In addition, single nucleotide polymorphisms (SNPs) in promoter regions ...

    Authors: Eun-Gyo Kim, Jung Oh Kim, Han Sung Park, Chang Soo Ryu, Jisu Oh, Hak Hoon Jun, Jong Woo Kim and Nam Keun Kim
    Citation: BMC Cancer 2019 19:480
    Content type: Research article Published on:

  7. Protease activated receptor-2 (PAR-2) has been implicated in cellular proliferation, invasion and metastasis in various tumors. Lymph node metastasis is an important patient prognostic factor for uterine cervi...

    Authors: Israt Jahan, Jiro Fujimoto, Syed Mahfuzul Alam, Eriko Sato and Teruhiko Tamaya
    Citation: BMC Cancer 2008 8:301
    Content type: Research article Published on:

  8. Deaf people represent 0.1% of the French population and their access to public health campaigns is limited due to their frequent illiteracy and the infrequent use of sign language in campaigns. There is also a...

    Authors: Vladimir Druel, Hélène Hayet, Laetitia Esman, Marie Clavel and Marie-Eve Rougé Bugat
    Citation: BMC Cancer 2018 18:93
    Content type: Research article Published on:

  9. In ovarian cancer, dysregulation of mRNA expression of several components of the family of the kallikrein-related peptidases (KLKs) is observed. In this study, we have analyzed the KLK5 mRNA expression pattern...

    Authors: Weiwei Gong, Yueyang Liu, Christof Seidl, Eleftherios P. Diamandis, Marion Kiechle, Enken Drecoll, Matthias Kotzsch, Viktor Magdolen and Julia Dorn
    Citation: BMC Cancer 2019 19:696
    Content type: Research article Published on:

  10. Although omic-based discovery approaches can provide powerful tools for biomarker identification, several reservations have been raised regarding the clinical applicability of gene expression studies, such as ...

    Authors: Patrick C O´Leary, Sarah A Penny, Roisin T Dolan, Catherine M Kelly, Stephen F Madden, Elton Rexhepaj, Donal J Brennan, Amanda H McCann, Fredrik Pontén, Mathias Uhlén, Radoslaw Zagozdzon, Michael J Duffy, Malcolm R Kell, Karin Jirström and William M Gallagher
    Citation: BMC Cancer 2013 13:175
    Content type: Research article Published on:

  11. This study is a retrospective evaluation of the efficacy of neoadjuvant chemotherapy (NC) with a vinorelbine (V) and epirubicin (E) intravenous combination regimen and is aimed at identification of predictive ...

    Authors: Ou Huang, CanMing Chen, JiaYi Wu, ShuJie Chen, XiaoSong Chen, GuangYu Liu, Zhen Hu, JingSong Lu, Jiong Wu, ZhiMin Shao, ZhenZhou Shen and KunWei Shen
    Citation: BMC Cancer 2009 9:375
    Content type: Research article Published on:

  12. Solitary metastasis of a malignancy to the spleen is rare, particularly for gastric cancer. Only a few case reports have documented isolated splenic metastasis from early gastric cancer. We describe a case of ...

    Authors: Junichi Yoshizawa, Naoki Kubo, Satoshi Ishizone, Fumitoshi Karasawa and Ataru Nakayama
    Citation: BMC Cancer 2017 17:436
    Content type: Case report Published on:

  15. The causal impact of lipid-lowering drugs on ovarian cancer (OC) and cervical cancer (CC) has received considerable attention, but its causal relationship is still a subject of debate. Hence, the objective of ...

    Authors: Jinshuai Li, Zixian Yang, Tao Wang, Mengqi Li, Xiangjian Wu, Xiaoyan Fu, Chunfeng Yang, Yangpu Li, Ximing Wang, Zhiming Lan, Minfang Li and Sheng Chen
    Citation: BMC Cancer 2024 24:667
    Content type: Research Published on:

  18. Small cell cervical carcinoma (SCCC) is a rare, aggressive tumor with a poor prognosis. However, information in relation to its treatment is scarce due to the limited numbers of patients. The aim of this study...

    Authors: Long Huang, Ling-Min Liao, An-Wen Liu, Jian-Bing Wu, Xiao-Ling Cheng, Jia-Xin Lin and Min Zheng
    Citation: BMC Cancer 2014 14:140
    Content type: Research article Published on:

  19. More than half of patients with colorectal cancer will develop metastatic disease either evident at the time of initial diagnosis or during their course of disease. Besides multidisciplinary management further...

    Authors: Alexander Stein, Gabriel Glockzin, Andreas Wienke, Dirk Arnold, Thomas Edelmann, Bert Hildebrandt, Stephan Hollerbach, Gerald Illerhaus, Alfred Königsrainer, Michael Richter, Hans J Schlitt and Hans-Joachim Schmoll
    Citation: BMC Cancer 2012 12:356
    Content type: Study protocol Published on:

  20. Previous epidemiological studies aimed at describing characteristics of breast (BC) and ovarian cancer (OC) patients tend to examine Hispanic populations using a mix of individuals that come from ethnically di...

    Authors: Ariel Rodriguez-Velazquez, Rosa Velez, Jean Carlo Lafontaine, Claudia B. Colon-Echevarria, Rocio D. Lamboy-Caraballo, Ingrid Ramirez, Adalberto Mendoza, Patricia Casbas-Hernandez and Guillermo N. Armaiz-Pena
    Citation: BMC Cancer 2018 18:1177
    Content type: Research article Published on:

  21. The association between alpha-1 antitrypsin (AAT) deficiency and colorectal cancer (CRC) is currently controversial. The present study compares AAT serum concentrations and gene frequencies between a group of ...

    Authors: Sergio Pérez-Holanda, Ignacio Blanco, Manuel Menéndez and Luis Rodrigo
    Citation: BMC Cancer 2014 14:355
    Content type: Research article Published on:

  22. Our group previously reported that tumour-specific expression of the rate-limiting enzyme in the mevalonate pathway, 3-hydroxy-3-methylglutharyl-coenzyme A reductase (HMG-CoAR) is associated with more favourab...

    Authors: Donal J Brennan, Jenny Brändstedt, Elton Rexhepaj, Michael Foley, Fredrik Pontén, Mathias Uhlén, William M Gallagher, Darran P O'Connor, Colm O'Herlihy and Karin Jirstrom
    Citation: BMC Cancer 2010 10:125
    Content type: Research article Published on:

  23. RAS/BRAFV600E mutations are the most remarkable oncogenic driver mutations in colorectal cancer (CRC) and play an important role in treatment selection. No data are available regarding the clinical and prognostic...

    Authors: Tatsuki Ikoma, Mototsugu Shimokawa, Masahito Kotaka, Toshihiko Matsumoto, Hiroki Nagai, Shogen Boku, Nobuhiro Shibata, Hisateru Yasui and Hironaga Satake
    Citation: BMC Cancer 2021 21:518
    Content type: Research Published on:

  24. Hypermethylation of DNA is an epigenetic alteration commonly found in colorectal cancer (CRC) and can also be detected in blood samples of cancer patients. Methylation of the genes helicase-like transcription ...

    Authors: Alexander B Philipp, Dorothea Nagel, Petra Stieber, Rolf Lamerz, Isabel Thalhammer, Andreas Herbst and Frank T Kolligs
    Citation: BMC Cancer 2014 14:245
    Content type: Research article Published on:

  25. The lymphocyte-to-monocyte ratio (LMR) has been used as a parameter reflecting systemic inflammation in several tumors, and is reportedly associated with prognosis in cancer patients. In this study, we evaluat...

    Authors: Wataru Goto, Shinichiro Kashiwagi, Yuka Asano, Koji Takada, Katsuyuki Takahashi, Takaharu Hatano, Tsutomu Takashima, Shuhei Tomita, Hisashi Motomura, Kosei Hirakawa and Masaichi Ohira
    Citation: BMC Cancer 2018 18:1137
    Content type: Research article Published on:

  26. As is well recognized that inflammation plays a crucial role in the genesis and progression of various cancer. Here we investigate the prognostic value of a novel index: the combination of neutrophil to lympho...

    Authors: Weihao Kong, Mingwei Yang, Jianfeng Zhang, Ya Cheng, Tianxing Dai, Jian Zhang, Guoying Wang and Jianlin Zhang
    Citation: BMC Cancer 2021 21:469
    Content type: Research article Published on:

  27. Chemoradiotherapy (CRT), which might affect the autonomic system, is the mainstay therapy for advanced esophageal squamous cell carcinoma (ESCC). Autonomic dysfunction has been found to possibly lead to cancer...

    Authors: Chen-Ling Tang, Wei-Chung Tsai, Jui-Ying Lee, Yao-Kuang Wang, Yi-Hsun Chen, Yu-Wei Liu, Ming-Chieh Lin, Pen-Tzu Fang, Yu-Ling Huang and I-Chen Wu
    Citation: BMC Cancer 2022 22:1086
    Content type: Research Published on:

  28. Bladder cancer (BC) is the fourth most prevalent neoplasm in men and is associated with high tumour recurrence rates, leading to major treatment challenges. Lysine-specific demethylase 6A (KDM6A) is frequently mu...

    Authors: Xingxing Chen, Xuehua Lin, Guofu Pang, Jian Deng, Qun Xie and Zhengrong Zhang
    Citation: BMC Cancer 2021 21:635
    Content type: Research Published on:

  29. The present study aimed to explore the application value of random survival forest (RSF) model and Cox model in predicting the progression-free survival (PFS) among patients with locoregionally advanced nasoph...

    Authors: Wei Pei, Chen Wang, Hai Liao, Xiaobo Chen, Yunyun Wei, Xia Huang, Xueli Liang, Huayan Bao, Danke Su and Guanqiao Jin
    Citation: BMC Cancer 2022 22:739
    Content type: Research Published on:

  30. Breast cancer is the most globally diagnosed female cancer, with the triple negative breast cancer (TNBC) being the most aggressive subtype of the disease. In this study we aimed at comparing the effect of BRC...

    Authors: Danielle Bogan, Lucio Meile, Ahmed El Bastawisy, Hend F. Yousef, Abdel-Rahman N. Zekri, Abeer A. Bahnassy and Wael M. ElShamy
    Citation: BMC Cancer 2017 17:329
    Content type: Research article Published on:

  31. Evidence suggests that truth telling and honest disclosure of cancer diagnosis could lead to improved outcomes in cancer patients. To examine such findings in Iran, this trial aimed to study the various dimens...

    Authors: Ali Montazeri, Azadeh Tavoli, Mohammad Ali Mohagheghi, Rasool Roshan and Zahra Tavoli
    Citation: BMC Cancer 2009 9:39
    Content type: Research article Published on:

  32. Human papillomavirus (HPV)-related head and neck cancer has been associated with an improved prognosis in patients treated with radiotherapy (RT) +/− chemotherapy (CT); however, RT combined with epidermal grow...

    Authors: Bella Pajares, Jose M Trigo, Maria D Toledo, Martina Álvarez, Carlos González-Hermoso, Antonio Rueda, Jose A Medina, Vanessa de Luque, Jose M Jerez and Emilio Alba
    Citation: BMC Cancer 2013 13:26
    Content type: Research article Published on:

  33. We aimed to explore the clinical benefit of adjuvant chemotherapy (AC) with fluoropyrimidine in patients with ypT0-3N0 rectal cancer after preoperative chemoradiation therapy (CRT) followed by total mesorectal...

    Authors: Chang Gon Kim, Joong Bae Ahn, Sang Joon Shin, Seung Hoon Beom, Su Jin Heo, Hyung Soon Park, Jee Hung Kim, Eun Ah Choe, Woong Sub Koom, Hyuk Hur, Byung Soh Min, Nam Kyu Kim, Hoguen Kim, Chan Kim, Inkyung Jung and Minkyu Jung
    Citation: BMC Cancer 2017 17:615
    Content type: Research article Published on:

  36. The lack of prognostic biomarkers in oral squamous cell carcinoma (OSCC) has hampered treatment decision making and survival in OSCC remains poor. Histopathological features are used for prognostication in OSC...

    Authors: Pinaki Bose, Nigel T Brockton, Kelly Guggisberg, Steven C Nakoneshny, Elizabeth Kornaga, Alexander C Klimowicz, Mauro Tambasco and Joseph C Dort
    Citation: BMC Cancer 2015 15:409
    Content type: Research article Published on:

  37. The SRY-related HMG-box family of transcription factors member SOX2 has been mainly studied in embryonic stem cells as well as early foregut and neural development. More recently, SOX2 was shown to participate in...

    Authors: Claudia Lengerke, Tanja Fehm, Ralf Kurth, Hans Neubauer, Veit Scheble, Friederike Müller, Friederike Schneider, Karen Petersen, Diethelm Wallwiener, Lothar Kanz, Falko Fend, Sven Perner, Petra M Bareiss and Annette Staebler
    Citation: BMC Cancer 2011 11:42
    Content type: Research article Published on:

  38. Psychiatric patients with colorectal cancer may have delayed diagnosis and be oncologically undertreated.

    Authors: Linda Kaerlev, Maria Iachina, Oleg Trosko, Niels Qvist, Pernille Møller Ljungdalh and Bente Mertz Nørgård
    Citation: BMC Cancer 2018 18:1050
    Content type: Research article Published on:

  39. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-derived reactive oxygen species (ROS) not only can promote cancer progression, but also they have recently emerged as mediators of the mucosal immune...

    Authors: Sang Yeon Cho, Sungha Kim, Mi-Ju Son, Gwanghun Kim, Parul Singh, Ha Neul Kim, Hei-Gwon Choi, Heon Jong Yoo, Young Bok Ko, Byung Seok Lee and Hyuk Soo Eun
    Citation: BMC Cancer 2019 19:1078
    Content type: Research article Published on:

  40. Little is known about the roles of Notch signaling in cholangiocarcinoma (CC). The expression of hairy and enhancer of split 1 (Hes-1) has not been investigated yet in resected specimens of CC. Notch signaling...

    Authors: Shuichi Aoki, Masamichi Mizuma, Yayoi Takahashi, Yoichi Haji, Ryo Okada, Tomoya Abe, Hideaki Karasawa, Keiichi Tamai, Takaho Okada, Takanori Morikawa, Hiroki Hayashi, Kei Nakagawa, Fuyuhiko Motoi, Takeshi Naitoh, Yu Katayose and Michiaki Unno
    Citation: BMC Cancer 2016 16:854
    Content type: Research article Published on:

  41. The basic helix-loop-helix transcription factor TWIST1 (Twist) is involved in embryonic cell lineage determination and mesodermal differentiation. There is evidence to indicate that Twist expression plays a ro...

    Authors: Farhad Vesuna, Yehudit Bergman and Venu Raman
    Citation: BMC Cancer 2017 17:52
    Content type: Research article Published on:

  42. We conducted a phase I/Ib, open-label, single-arm trial to assess the safety, tolerability and optimal scheduling regimen of OTSGC-A24 cancer vaccine in patients with advanced gastric cancer.

    Authors: Raghav Sundar, Sun Young Rha, Hiroki Yamaue, Masahiro Katsuda, Koji Kono, Hyo Song Kim, Chan Kim, Kousaku Mimura, Ley-Fang Kua and Wei Peng Yong
    Citation: BMC Cancer 2018 18:332
    Content type: Research article Published on:

  43. There is still controversy regarding the clinical value and significance of lateral pelvic lymph node (LPN) dissection (LPND). The present study aimed to investigate whether the addition of LPND to total mesor...

    Authors: Sicheng Zhou, Yujuan Jiang, Wei Pei, Jianwei Liang and Zhixiang Zhou
    Citation: BMC Cancer 2022 22:136
    Content type: Research Published on:

  44. To analyze trends in cancer incidence and mortality (France, 1990–2018), with a focus on men-women disparities.

    Authors: G. Defossez, Z. Uhry, P. Delafosse, E. Dantony, T. d’Almeida, S. Plouvier, N. Bossard, A. M. Bouvier, F. Molinié, A. S. Woronoff, M. Colonna, P. Grosclaude, L. Remontet and A. Monnereau
    Citation: BMC Cancer 2021 21:726
    Content type: Research Published on:

  45. Tumor-infiltrating lymphocytes (TILs) play a critical role in tumor immune surveillance and immune suppression. Understanding tumor infiltrating T cell subset density, location and PD-1/PD-L1 expression might ...

    Authors: Feng Jiang, Wei Yu, Fanrui Zeng, Guoping Cheng, Jing Xu, Shifeng Yang, Yongjie Shui, Dang Wu, Xiao-fang Yu and Qichun Wei
    Citation: BMC Cancer 2019 19:503
    Content type: Research article Published on:

  46. Peritoneal metastasis is one of the main causes of death in patients with gastric cancer (GC). Galectin-1 regulates various undesirable biological behaviors in GC and may be key in GC peritoneal metastasis.

    Authors: Xianhe Shen, Huilan Liu, Haihua Zhou, Zhiyi Cheng, Guiyuan Liu, Chuanjiang Huang, Rongrong Dou, Fuxing Liu and Xiaolan You
    Citation: BMC Cancer 2023 23:559
    Content type: Research Published on:

  47. Gallbladder cancer is a rare malignancy of the biliary tract with a poor prognosis, frequently presenting at an advanced stage. While rare in the United States overall, gallbladder cancer has an elevated incid...

    Authors: Jacklyn M. Nemunaitis, Ursa Brown-Glabeman, Heloisa Soares, Jessica Belmonte, Ben Liem, Itzhak Nir, Victor Phuoc and Rama R. Gullapalli
    Citation: BMC Cancer 2018 18:665
    Content type: Review Published on:

  49. Carbonic anhydrase 9 (CA9) is a marker for hypoxia and acidosis, which is linked to a poor prognosis in human tumors. The purpose of this comparative analysis was to evaluate whether CA9 and VEGF expression ar...

    Authors: Yong Sang Hong, Hyeon Jin Cho, Sun Young Kim, Kyung Hae Jung, Ji Won Park, Hyo Seong Choi, Jae Hwan Oh, Byung Chang Kim, Dae Kyung Sohn, Dae Yong Kim and Hee Jin Chang
    Citation: BMC Cancer 2009 9:246
    Content type: Research article Published on:

  50. Breast cancer (BC) patients with late-stage and/or rapidly growing tumors are prone to develop high serum calcium levels which have been shown to be associated with larger and aggressive breast tumors in post ...

    Authors: Li Wang, Sarrah E. Widatalla, Diva S. Whalen, Josiah Ochieng and Amos M. Sakwe
    Citation: BMC Cancer 2017 17:511
    Content type: Research article Published on:

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