Skip to main content

Articles

Page 179 of 335

  1. Triple-negative breast cancer (TN) is more aggressive than other subtypes of breast cancer and has a lower survival rate. Furthermore, detailed biological information about the disease is lacking. This study i...

    Authors: Yuji Yamashita, Shin Nishiumi, Seishi Kono, Shintaro Takao, Takeshi Azuma and Masaru Yoshida
    Citation: BMC Cancer 2017 17:589
    Content type: Research article Published on:

  2. DNA methylation changes occurring in cancer cells are featured with both promoter CpG island hypermethylation and diffuse genomic hypomethylation. Long interspersed element-1 (LINE-1) is repeated in an intersp...

    Authors: Seorin Jeong, Kyoungbun Lee, Xianyu Wen, Younghoon Kim, Nam-Yun Cho, Ja-June Jang and Gyeong Hoon Kang
    Citation: BMC Cancer 2017 17:588
    Content type: Research article Published on:

  3. The FOLFOX regimen, i.e., folinic acid (FOL), fluorouracil (F) and oxaliplatin (OX), is a drug cocktail that is used to treat gastric and colorectal cancers. Despite the concomitant improvements in response ra...

    Authors: Annick De Weerdt, Amélie Dendooven, Annemie Snoeckx, Jan Pen, Martin Lammens and Philippe G. Jorens
    Citation: BMC Cancer 2017 17:586
    Content type: Case report Published on:

  4. Venous thromboembolic events (VTE) are common in cancer patients and associated with higher mortality. In vivo thrombosis and anticoagulation might be involved in tumor growth and progression. We studied the a...

    Authors: Pete T. T. Kinnunen, Teemu J. Murtola, Kirsi Talala, Kimmo Taari, Teuvo L. J. Tammela and Anssi Auvinen
    Citation: BMC Cancer 2017 17:585
    Content type: Research article Published on:

  5. Epithelial-mesenchymal transition (EMT), principally involving an E-cadherin to N-cadherin shift, linked to tumor invasion or metastasis, and therapeutic resistance in various human cancer. A growing body of r...

    Authors: Myung-Giun Noh, Se-Jeong Oh, Eun-Jung Ahn, Yeong-Jin Kim, Tae-Young Jung, Shin Jung, Kyung-Keun Kim, Jae-Hyuk Lee, Kyung-Hwa Lee and Kyung-Sub Moon
    Citation: BMC Cancer 2017 17:583
    Content type: Research article Published on:

  6. Using propensity score matching method (PSM) to evaluate the feasibility and clinical outcomes of simultaneous modulated accelerated radiation therapy (SMART) using helical tomotherapy (HT) in patients with na...

    Authors: Lei Du, Xin-Xin Zhang, Lin-Chun Feng, Bao-Lin Qu, Jing Chen, Jun Yang, Hai-Xia Liu, Shou-Ping Xu, Chuan-Bin Xie and Lin Ma
    Citation: BMC Cancer 2017 17:582
    Content type: Research article Published on:

  7. The effect of endocrine therapy with tamoxifen (TMX) on weight gain has been reported in the literature, but the outcomes are still controversial. Moreover, previous treatment options, such as chemotherapy (CT...

    Authors: Mariana Tavares Miranda Lima, Kamila Pires de Carvalho, Fernanda Silva Mazzutti, Marcelo de Almeida Maia, Paula Philbert Lajolo Canto, Carlos Eduardo Paiva and Yara Cristina de Paiva Maia
    Citation: BMC Cancer 2017 17:578
    Content type: Research article Published on:

  8. The Basque Colorectal Cancer Screening Programme has both high participation rate and high compliance rate of colonoscopy after a positive faecal occult blood test (FIT). Although, colorectal cancer (CRC) scre...

    Authors: Eunate Arana-Arri, Isabel Idigoras, Begoña Uranga, Raquel Pérez, Ana Irurzun, Iñaki Gutiérrez-Ibarluzea, Callum G. Fraser and Isabel Portillo
    Citation: BMC Cancer 2017 17:577
    Content type: Research article Published on:

  9. Racial disparities exist in the care provided to advanced cancer patients. This article describes an investigation designed to advance the science of healthcare disparities by isolating the effects of patient ...

    Authors: Cezanne M. Elias, Cleveland G. Shields, Jennifer J. Griggs, Kevin Fiscella, Sharon L. Christ, Joseph Colbert, Stephen G. Henry, Beth G. Hoh, Haslyn E. R. Hunte, Mary Marshall, Supriya Gupta Mohile, Sandy Plumb, Mohamedtaki A. Tejani, Alison Venuti and Ronald M. Epstein
    Citation: BMC Cancer 2017 17:575
    Content type: Study protocol Published on:

  10. The squamous cell carcinoma of the anus (SCCA) is a rare disease, but its incidence is markedly increasing. About 15% of patients are diagnosed at metastatic stage, and more than 20% with a localized disease t...

    Authors: Stefano Kim, Marine Jary, Thierry André, Véronique Vendrely, Bruno Buecher, Eric François, François-Clément Bidard, Sarah Dumont, Emmanuelle Samalin, Didier Peiffert, Simon Pernot, Nabil Baba-Hamed, Farid El Hajbi, Olivier Bouché, Jérôme Desrame, Aurélie Parzy…
    Citation: BMC Cancer 2017 17:574
    Content type: Study protocol Published on:

  11. To compare the PSA value at the last follow-up of patients who underwent prostate low-dose rate brachytherapy (LDR-BT) with that of patients who underwent intensity-modulated radiation therapy (IMRT).

    Authors: Nobumichi Tanaka, Isao Asakawa, Yasushi Nakai, Makito Miyake, Satoshi Anai, Tomomi Fujii, Masatoshi Hasegawa, Noboru Konishi and Kiyohide Fujimoto
    Citation: BMC Cancer 2017 17:573
    Content type: Research article Published on:

  12. Tumor-specific biomarkers are a prerequisite for the development of targeted imaging and therapy in oral squamous cell carcinoma (OSCC). urokinase-type Plasminogen Activator Receptor (uPAR), Tissue Factor (TF)...

    Authors: Anders Christensen, Katalin Kiss, Giedrius Lelkaitis, Karina Juhl, Morten Persson, Birgitte Wittenborg Charabi, Jann Mortensen, Julie Lyng Forman, Anne Lyngholm Sørensen, David Hebbelstrup Jensen, Andreas Kjaer and Christian von Buchwald
    Citation: BMC Cancer 2017 17:572
    Content type: Research article Published on:

  13. Elderly patient with advanced cancer is one of the most vulnerable populations. Skeletal muscle depletion during chemotherapy may have substantial impact on their physical function. However, there is little in...

    Authors: Tateaki Naito, Taro Okayama, Takashi Aoyama, Takuya Ohashi, Yoshiyuki Masuda, Madoka Kimura, Hitomi Shiozaki, Haruyasu Murakami, Hirotsugu Kenmotsu, Tetsuhiko Taira, Akira Ono, Kazushige Wakuda, Hisao Imai, Takuya Oyakawa, Takeshi Ishii, Shota Omori…
    Citation: BMC Cancer 2017 17:571
    Content type: Research article Published on:

  16. Studies have indicated a pervasive pattern of decreasing healthcare costs during elderly patients’ last year of life. The aim of this study was to explore the predictors of high healthcare costs (HC) in elderl...

    Authors: Jui-Kun Chiang and Yee-Hsin Kao
    Citation: BMC Cancer 2017 17:568
    Content type: Research article Published on:

  17. This study aimed to evaluate the long-term outcome and toxicities in patients with locoregionally advanced nasopharyngeal carcinoma (NPC) treated by concurrent chemoradiotherapy (CCRT) with/without adding cetu...

    Authors: Yang Li, Qiu-Yan Chen, Lin-Quan Tang, Li-Ting Liu, Shan-Shan Guo, Ling Guo, Hao-Yuan Mo, Ming-Yuan Chen, Xiang Guo, Ka-Jia Cao, Chao-Nan Qian, Mu-Shen Zeng, Jin-Xin Bei, Jian-Yong Shao, Ying Sun, Jing Tan…
    Citation: BMC Cancer 2017 17:567
    Content type: Research article Published on:

  19. Maintenance therapy (MT) with pemetrexed has been shown to improve overall and progression-free survival of patients with non-squamous non-small cell lung cancer (NSCLC), without impairing patients’ health-rel...

    Authors: Monika Sztankay, Johannes Maria Giesinger, August Zabernigg, Elisabeth Krempler, Georg Pall, Wolfgang Hilbe, Otto Burghuber, Maximilian Hochmair, Gerhard Rumpold, Stephan Doering and Bernhard Holzner
    Citation: BMC Cancer 2017 17:565
    Content type: Research article Published on:

  20. The aim of this study was to assess the feasibility and potential benefit of a brief psychosocial intervention based on cognitive-behavioral therapy performed in addition to early palliative care (PC) in the r...

    Authors: Thamires Monteiro do Carmo, Bianca Sakamoto Ribeiro Paiva, Cleyton Zanardo de Oliveira, Maria Salete de Angelis Nascimento and Carlos Eduardo Paiva
    Citation: BMC Cancer 2017 17:564
    Content type: Research article Published on:

  22. Previous studies have investigated the protective effect of vitamin D serum levels, at diagnosis and during the follow-up period after treatment, on melanoma outcome. In the present study we assess whether vit...

    Authors: J. De Smedt, S. Van Kelst, V. Boecxstaens, M. Stas, K. Bogaerts, D. Vanderschueren, C. Aura, K. Vandenberghe, D. Lambrechts, P. Wolter, O. Bechter, A. Nikkels, T. Strobbe, G. Emri, V. Marasigan and M. Garmyn
    Citation: BMC Cancer 2017 17:562
    Content type: Study protocol Published on:

  24. The effect of early palliative care and rehabilitation on the quality of life of patients with advanced cancer has been only sparsely described and needs further investigation. In the present trial we combine ...

    Authors: Lise Nottelmann, Mogens Groenvold, Tove Bahn Vejlgaard, Morten Aagaard Petersen and Lars Henrik Jensen
    Citation: BMC Cancer 2017 17:560
    Content type: Study protocol Published on:

  25. The global burden of hematologic malignancy (HM) is rapidly rising with aging, exposure to polluted environments, and global and local climate variability all being well-established conditions of oxidative str...

    Authors: Mireille Solange Nganga Nkanga, Benjamin Longo-Mbenza, Oladele Vincent Adeniyi, Jacques Bikaula Ngwidiwo, Antoine Lufimbo Katawandja, Paul Roger Beia Kazadi and Alain Nganga Nzonzila
    Citation: BMC Cancer 2017 17:559
    Content type: Research article Published on:

  26. The relationship between the number of harvested lymph nodes (HLNs) and prognosis of gastric cancer patients without an involvement of lymph nodes has not been well-evaluated. The objective of this study is to...

    Authors: Xin Ji, Zhao-De Bu, Zi-Yu Li, Ai-Wen Wu, Lian-Hai Zhang, Ji Zhang, Xiao-Jiang Wu, Xiang-Long Zong, Shuang-Xi Li, Fei Shan, Zi-Yu Jia and Jia-Fu Ji
    Citation: BMC Cancer 2017 17:558
    Content type: Research article Published on:

  27. Various studies have reported that the neutrophil-to-lymphocyte ratio in the serum (sNLR) may serve as a cost-effective and useful prognostic factor in patients with various cancer types. However, no study has...

    Authors: Yong Seok Lee, Hae-Seong Nam, Jun Hyeok Lim, Jung Soo Kim, Yeonsook Moon, Jae Hwa Cho, Jeong-Seon Ryu, Seung Min Kwak and Hong Lyeol Lee
    Citation: BMC Cancer 2017 17:557
    Content type: Research article Published on:

  28. No scientific consensus has been reached on whether active tobacco smoking causes breast cancer. We examine the association between active smoking and breast cancer risk in Denmark, which has some of the highe...

    Authors: Zorana Jovanovic Andersen, Jeanette Therming Jørgensen, Randi Grøn, Elvira Vaclavik Brauner and Elsebeth Lynge
    Citation: BMC Cancer 2017 17:556
    Content type: Research article Published on:

  29. The Empty Spiracles Homeobox (EMX-) 2 gene has been associated with regulation of growth and differentiation in neuronal development. While recent studies provide evidence that EMX2 regulates tumorigenesis of ...

    Authors: Berk Aykut, Markus Ochs, Praveen Radhakrishnan, Adrian Brill, Hermine Höcker, Sandra Schwarz, Daniel Weissinger, Roland Kehm, Yakup Kulu, Alexis Ulrich and Martin Schneider
    Citation: BMC Cancer 2017 17:555
    Content type: Research article Published on:

  30. Intraoperative blood loss during hepatectomy worsens prognosis, and various tools have been used to improve perioperative safety and feasibility. We aimed to retrospectively evaluate the feasibility and safety...

    Authors: Yi-jun Zhao, Da-chen Zhou, Fu-bao Liu, Hong-chuan Zhao, Guo-bin Wang and Xiao-ping Geng
    Citation: BMC Cancer 2017 17:554
    Content type: Research article Published on:

  31. Opioid receptors have become increasingly implicated in cancer progression and long-term patient outcomes. However, the expression and significance of the κ-opioid receptor (KOR) in hepatocellular carcinoma (H...

    Authors: Dongtai Chen, Yonghua Chen, Yan Yan, Jiahao Pan, Wei Xing, Qiang Li and Weian Zeng
    Citation: BMC Cancer 2017 17:553
    Content type: Research article Published on:

  32. Following esophagectomy, esophageal cancer patients experience a clinically relevant deterioration of health-related quality of life, both on the short- and long-term. With the currently growing number of esop...

    Authors: Jonna K. van Vulpen, Peter D. Siersema, Richard van Hillegersberg, Grard A. P. Nieuwenhuijzen, Ewout A. Kouwenhoven, Richard P. R. Groenendijk, Donald L. van der Peet, Eric J. Hazebroek, Camiel Rosman, Carlo C. G. Schippers, Elles Steenhagen, Petra H. M. Peeters and Anne M. May
    Citation: BMC Cancer 2017 17:552
    Content type: Study protocol Published on:

  33. Adoptive T-cell therapy relying on conventional T cells transduced with T-cell receptors (TCRs) or chimeric antigen receptors (CARs) has caused substantial tumor regression in several clinical trials. However,...

    Authors: Dennis C. Harrer, Bianca Simon, Shin-ichiro Fujii, Kanako Shimizu, Ugur Uslu, Gerold Schuler, Kerstin F. Gerer, Stefanie Hoyer, Jan Dörrie and Niels Schaft
    Citation: BMC Cancer 2017 17:551
    Content type: Research article Published on:

  34. Community misconception of what causes cancer is an important consideration when devising communication strategies around cancer prevention, while those initiating social marketing campaigns must decide whethe...

    Authors: Rebecca Kippen, Erica James, Bernadette Ward, Penny Buykx, Ardel Shamsullah, Wendy Watson and Kathy Chapman
    Citation: BMC Cancer 2017 17:550
    Content type: Research article Published on:

  35. New generation hormone-therapies (NGHT) targeting the androgen signalling pathway are nowadays proposed to elderly patients with metastatic castration-resistant prostate cancer (CRPCa). The impact of these tre...

    Authors: Marie Lange, Heidi Laviec, Hélène Castel, Natacha Heutte, Alexandra Leconte, Isabelle Léger, Bénédicte Giffard, Aurélie Capel, Martine Dubois, Bénédicte Clarisse, Elodie Coquan, Frédéric Di Fiore, Sophie Gouérant, Philippe Bartélémy, Laure Pierard, Karim Fizazi…
    Citation: BMC Cancer 2017 17:549
    Content type: Study protocol Published on:

    The Correction to this article has been published in BMC Cancer 2018 18:110

  36. Metastatic colorectal cancer (mCRC) is a disease of older age, but there is a relative lack of knowledge about effects of chemotherapy in older patients as they are under-represented in clinical trials. Little...

    Authors: Stine Braendegaard Winther, Pia Österlund, Åke Berglund, Bengt Glimelius, Camilla Qvortrup, Halfdan Sorbye and Per Pfeiffer
    Citation: BMC Cancer 2017 17:548
    Content type: Study protocol Published on:

  37. Vascular endothelial growth factor (VEGF) directed therapies are being used in a large number of advanced tumors. Metastatic renal cell carcinoma (mRCC) is highly dependent on the VEGF pathway; VEGF receptor (...

    Authors: Sylvie Négrier, David Pérol, Rastislav Bahleda, Antoine Hollebecque, Etienne Chatelut, Helen Boyle, Philippe Cassier, Séverine Metzger, Ellen Blanc, Jean-Charles Soria and Bernard Escudier
    Citation: BMC Cancer 2017 17:547
    Content type: Research article Published on:

  38. During cancer progression, epithelial cancer cells can be reprogrammed into mesenchymal-like cells with increased migratory potential through the process of epithelial-mesenchymal transition (EMT), representin...

    Authors: Lucia Sommerova, Eva Ondrouskova, Borivoj Vojtesek and Roman Hrstka
    Citation: BMC Cancer 2017 17:546
    Content type: Research article Published on:

  39. Real-time polymerase chain reaction (PCR) has become an increasingly important technique for gene expression profiling because it can provide insights into complex biological and pathological processes and be ...

    Authors: Xi Wu, Susu Liu, Jianjun Lyu, Shuya Zhou, Yanwei Yang, Chenfei Wang, Wenda Gu, Qin Zuo, Baowen Li and Changfa Fan
    Citation: BMC Cancer 2017 17:545
    Content type: Research article Published on:

  40. The levels of liver function tests (LFTs) are often used to assess liver injury and non-liver disease-related mortality. In our study, the relationship between pretreatment serum LFTs and overall survival (OS)...

    Authors: Hao Huang, Xue-Ping Wang, Xiao-Hui Li, Hao Chen, Xin Zheng, Jian-Hua Lin, Ting Kang, Lin Zhang and Pei-Song Chen
    Citation: BMC Cancer 2017 17:544
    Content type: Research article Published on:

  41. Uptake of colorectal cancer screening is low in the English NHS Bowel Cancer Screening Programme (BCSP). Participation in screening is strongly associated with socioeconomic status. The aim of this study was t...

    Authors: Samuel G. Smith, Jane Wardle, Wendy Atkin, Rosalind Raine, Lesley M. McGregor, Gemma Vart, Steve Morris, Stephen W. Duffy, Susan Moss, Allan Hackshaw, Stephen Halloran, Ines Kralj-Hans, Rosemary Howe, Julia Snowball, Graham Handley, Richard F. Logan…
    Citation: BMC Cancer 2017 17:543
    Content type: Research article Published on:

  42. Chronic angiogenesis is a hallmark of most tumors and takes place in a hostile tumor microenvironment (TME) characterized by hypoxia, low nutrient and glucose levels, elevated lactate and low pH. Despite this,...

    Authors: A. K. Pedersen, J. Mendes Lopes de Melo, N. Mørup, K. Tritsaris and S. F. Pedersen
    Citation: BMC Cancer 2017 17:542
    Content type: Research article Published on:

  43. To assess the outcomes and prognostic factors associated with palliative external beam radiotherapy (EBRT), administered to patients with advanced gastric cancer.

    Authors: Yun Hee Lee, Jeong Won Lee and Hong Seok Jang
    Citation: BMC Cancer 2017 17:541
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Cancer 2018 18:232

  44. Mutations of the DNA repair proteins BRCA1/2 are synthetically lethal with the DNA repair enzyme poly(ADP-ribose) polymerase (PARP), which when inhibited, leads to cell death due to the absence of compensatory...

    Authors: Zhor Senhaji Mouhri, Elliot Goodfellow and Bertrand Jean-Claude
    Citation: BMC Cancer 2017 17:540
    Content type: Research article Published on:

  45. Angipoietin-1 activation of the tyrosine kinase receptor Tek expressed mainly on endothelial cells leads to survival and stabilization of endothelial cells. Studies have shown that Angiopoietin-1 counteracts p...

    Authors: Iacovos P. Michael, Martina Orebrand, Marta Lima, Beatriz Pereira, Olga Volpert, Susan E. Quaggin and Marie Jeansson
    Citation: BMC Cancer 2017 17:539
    Content type: Research article Published on:

  46. Mantle cell lymphoma (MCL) is a B-cell hemopathy characterized by the t(11;14) translocation and the aberrant overexpression of cyclin D1. This results in an unrestrained cell proliferation. Other genetic alte...

    Authors: Khaoula Ben Younes, Simon Body, Élodie Costé, Pierre-Julien Viailly, Hadjer Miloudi, Clémence Coudre, Fabrice Jardin, Fatma Ben Aissa-Fennira and Brigitte Sola
    Citation: BMC Cancer 2017 17:538
    Content type: Research article Published on:

  47. A new 5-tiered grading grouping system has recently been endorsed for reporting of prostate cancer (PCa) grade to better reflect escalating risk of progression and cancer death. While several validations of th...

    Authors: K. R. Beckmann, A. D. Vincent, M. E. O’Callaghan, P. Cohen, S. Chang, M. Borg, S. M. Evans, D. M. Roder and K. L. Moretti
    Citation: BMC Cancer 2017 17:537
    Content type: Research article Published on:

  48. Hotspot mutations of the oncogenes BRAF and NRAS are the most common genetic alterations in cutaneous melanoma. Specific inhibitors of BRAF and MEK have shown significant survival benefits in large phase III t...

    Authors: Markus V. Heppt, Timo Siepmann, Jutta Engel, Gabriele Schubert-Fritschle, Renate Eckel, Laura Mirlach, Thomas Kirchner, Andreas Jung, Anja Gesierich, Thomas Ruzicka, Michael J. Flaig and Carola Berking
    Citation: BMC Cancer 2017 17:536
    Content type: Research article Published on:

  49. Patient-derived xenograft (PDX) models are important tools in precision medicine and for the development of targeted therapies to treat cancer patients. This study aimed to evaluate our precision medicine stra...

    Authors: Doo-Yi Oh, Kyungsoo Jung, Ji-Young Song, Seokhwi Kim, Sang Shin, Yong-Jun Kwon, Ensel Oh, Woong-Yang Park, Sang Yong Song and Yoon-La Choi
    Citation: BMC Cancer 2017 17:535
    Content type: Research article Published on:

  50. The incidence of acute erythroid leukemia subtype (AEL) is rare, accounting for 5% of cases of acute myeloid leukemia (AML), and the outcome is dismal. However, in 2016 revision to the WHO classification, the ...

    Authors: Shaowei Qiu, Erlie Jiang, Hui Wei, Dong Lin, Guangji Zhang, Shuning Wei, Chunlin Zhou, Kaiqi Liu, Ying Wang, Bingcheng Liu, Yuntao Liu, Benfa Gong, Xiaoyuan Gong, Sizhou Feng, Yingchang Mi, Mingzhe Han…
    Citation: BMC Cancer 2017 17:534
    Content type: Research article Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Follow

BMC Cancer

ISSN: 1471-2407

Contact us