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906 result(s) within Volume 17 of BMC Cancer

Page 15 of 19

  1. The scientific and public debate concerning organized mammography screening is unprecedentedly strong. With research evidence concerning its efficacy being ambiguous, the recommendations pertaining to the age-...

    Authors: Nanon H. M. Labrie, Ramona Ludolph and Peter J. Schulz
    Citation: BMC Cancer 2017 17:209
    Content type: Research article Published on:

  2. Autotransplantation of frozen-thawed ovarian tissue is a method to preserve ovarian function and fertility in patients undergoing gonadotoxic therapy. In oncology patients, the safety cannot yet be guaranteed,...

    Authors: Inge T. A. Peters, Merle A. van der Steen, Bertine W. Huisman, Carina G. J .M. Hilders, Vincent T. H. B. M. Smit, Alexander L. Vahrmeijer, Cornelis F. M. Sier, J. Baptist Trimbos and Peter J. K. Kuppen
    Citation: BMC Cancer 2017 17:206
    Content type: Research article Published on:

  3. Glioblastoma multiforme (GBM) is the most common, invasive and deadly primary type of malignant brain tumor. The Phosphatidylinositol-3-Kinase/AKT (PI3K/AKT) pathway is highly active in GBM and has been associ...

    Authors: Ravi S. Narayan, Carlos A. Fedrigo, Eelke Brands, Rogier Dik, Lukas J.A. Stalpers, Brigitta G. Baumert, Ben J. Slotman, Bart A. Westerman, Godefridus J. Peters and Peter Sminia
    Citation: BMC Cancer 2017 17:204
    Content type: Research article Published on:

  4. About 75–80% of breast tumors express the estrogen receptor alpha (ER-α) and are treated with endocrine-target therapeutics, making this the premier therapeutic modality in the breast cancer clinic. However, a...

    Authors: Mercè Padró, Raymond J. Louie, Brian V. Lananna, Adam J. Krieg, Luika A. Timmerman and Denise A. Chan
    Citation: BMC Cancer 2017 17:203
    Content type: Research article Published on:

  5. Tumour metastasis remains the major cause of death in cancer patients and, to date, the mechanism and signalling pathways governing this process are not completely understood. The TGF-β pathway is the most com...

    Authors: Jo-Anne de la Mare, Tamarin Jurgens and Adrienne L. Edkins
    Citation: BMC Cancer 2017 17:202
    Content type: Research article Published on:

  6. Y-box binding protein-1 is an evolutionary conserved transcription and translation regulating protein that is overexpressed in various human malignancies, including breast cancer. Despite reports of YB-1 and i...

    Authors: Jia Pei Lim, Sukanya Shyamasundar, Jayantha Gunaratne, Olivia Jane Scully, Ken Matsumoto and Boon Huat Bay
    Citation: BMC Cancer 2017 17:201
    Content type: Research article Published on:

  7. Aprepitant is an FDA-approved medication for chemotherapy-induced nausea and vomiting. It blocks substance P binding to neurokinin-1; substance P has been implicated in itch pathways both as a local and global...

    Authors: Johanna S. Song, Marianne Tawa, Nicole G. Chau, Thomas S. Kupper and Nicole R. LeBoeuf
    Citation: BMC Cancer 2017 17:200
    Content type: Case report Published on:

  8. Approximately 18–20% of all human breast cancers have overexpressed human epidermal growth factor receptor 2 (HER2). Standard clinical practice is to treat only overexpressed HER2 (HER2+) cancers with targeted...

    Authors: Yao Huang, David J. Burns, Benjamin E. Rich, Ian A. MacNeil, Abhijit Dandapat, Sajjad M. Soltani, Samantha Myhre, Brian F. Sullivan, Carol A. Lange, Leo T. Furcht and Lance G. Laing
    Citation: BMC Cancer 2017 17:199
    Content type: Research article Published on:

  9. Median age at diagnosis of patients with chronic lymphocytic leukemia (CLL) is > 70 years. However, the majority of clinical trials do not reflect the demographics of CLL patients treated in the community. We ...

    Authors: Chadi Nabhan, Anthony Mato, Christopher R. Flowers, David L. Grinblatt, Nicole Lamanna, Mark A. Weiss, Matthew S. Davids, Arlene S. Swern, Shriya Bhushan, Kristen Sullivan, E. Dawn Flick, Pavel Kiselev and Jeff P. Sharman
    Citation: BMC Cancer 2017 17:198
    Content type: Research article Published on:

  10. Collision tumors are uncommon but well described clinical entities composed of distinct tumor histologies occurring within the same anatomic site. Optimal management of patients with collision tumors remains h...

    Authors: Munveer S. Bhangoo, Jenny Y. Zhou, Siraj M. Ali, Russell Madison, Alexa B. Schrock and Carrie Costantini
    Citation: BMC Cancer 2017 17:197
    Content type: Case report Published on:

  11. Authors: Debra Anderson, Charrlotte Seib, Dian Tjondronegoro, Jane Turner, Leanne Monterosso, Amanda McGuire, Janine Porter-Steele, Wei Song, Patsy Yates, Neil King, Leonie Young, Kate White, Kathryn Lee, Sonj Hall, Mei Krishnasamy, Kathy Wells…
    Citation: BMC Cancer 2017 17:196
    Content type: Erratum Published on:

    The original article was published in BMC Cancer 2017 17:98

  12. Authors: Rumyana Ivanova Dodova, Atanaska Velichkova Mitkova, Daniela Rosenova Dacheva, Lina Basam Hadjo, Alexandrina Ivanova Vlahova, Margarita Stoyanova Taushanova – Hadjieva, Spartak Stoyanov Valev, Marija Mitko Caulevska, Stanislava Dimitrova Popova, Ivan Emilov Popov, Tihomir Iliichev Dikov, Theophil Angelov Sedloev, Atanas Stefanov Ionkov, Konstanta Velinova Timcheva, Svetlana Liubomirova Christova, Ivo Marinov Kremensky…
    Citation: BMC Cancer 2017 17:195
    Content type: Erratum Published on:

    The original article was published in BMC Cancer 2015 15:523

  13. Breast cancer is the main cause of mortality among women. The disease presents high recurrence mainly due to incomplete efficacy of primary treatment in killing all cancer cells. Photodynamic therapy (PDT), an...

    Authors: Ancély F. dos Santos, Letícia F. Terra, Rosangela A. M. Wailemann, Talita C. Oliveira, Vinícius de Morais Gomes, Marcela Franco Mineiro, Flávia Carla Meotti, Alexandre Bruni-Cardoso, Maurício S. Baptista and Leticia Labriola
    Citation: BMC Cancer 2017 17:194
    Content type: Research article Published on:

  14. This RCT with two parallel arms will evaluate the efficacy of an internet-delivered transdiagnostic cognitive behavioural therapy (iCBT) intervention for the treatment of clinical depression and/or anxiety in ...

    Authors: M. J. Murphy, J. M. Newby, P. Butow, L. Kirsten, K. Allison, S. Loughnan, M. A. Price, J. Shaw, H. Shepherd, J. Smith and G. Andrews
    Citation: BMC Cancer 2017 17:193
    Content type: Study protocol Published on:

    The Correction to this article has been published in BMC Cancer 2017 17:667

  15. Renal cell carcinomas (RCCs) overexpress fatty acid binding protein 7 (FABP7). We chose to study the TUHR14TKB cell line, because it expresses higher levels of FABP7 than other cell lines derived from renal ca...

    Authors: Naohisa Takaoka, Tatsuya Takayama and Seiichiro Ozono
    Citation: BMC Cancer 2017 17:192
    Content type: Research article Published on:

  16. Targeted therapies are emerging treatment options for gastric cancer (GC). Patient-derived tumor xenograft(PDX) models of GC closely retain the features of the original clinical cancer, offering a powerful too...

    Authors: Haiyong Wang, Jun Lu, Jian Tang, Shitu Chen, Kuifeng He, Xiaoxia Jiang, Weiqin Jiang and Lisong Teng
    Citation: BMC Cancer 2017 17:191
    Content type: Research article Published on:

  17. Cancer cachexia is a multifactorial syndrome that dramatically decreases survival. Loss of white adipose tissue (WAT) is one of the key characteristics of cachexia. WAT wasting is paralleled by microarchitectu...

    Authors: Michele Joana Alves, Raquel Galvão Figuerêdo, Flavia Figueiredo Azevedo, Diego Alexandre Cavallaro, Nelson Inácio Pinto Neto, Joanna Darck Carola Lima, Emidio Matos-Neto, Katrin Radloff, Daniela Mendes Riccardi, Rodolfo Gonzalez Camargo, Paulo Sérgio Martins De Alcântara, José Pinhata Otoch, Miguel Luiz Batista Junior and Marília Seelaender
    Citation: BMC Cancer 2017 17:190
    Content type: Research article Published on:

  18. The inhibition of Delta-like 4 (Dll4)/Notch signaling has been shown to result in excessive, nonfunctional vessel proliferation and significant tumor growth suppression. However, safety concerns emerged with t...

    Authors: Alexandre Trindade, Dusan Djokovic, Joana Gigante, Liliana Mendonça and António Duarte
    Citation: BMC Cancer 2017 17:189
    Content type: Research article Published on:

  19. To evaluate the efficacy of cetuximab combined with modified FOLFIRI (mFOLFIRI) as a second-line treatment in metastatic gastric cancer patients and to identify potential biomarkers of clinical outcomes.

    Authors: Xin Liu, Weijian Guo, Wen Zhang, Jiliang Yin, Jun Zhang, Xiaodong Zhu, Tianshu Liu, Zhiyu Chen, Biyun Wang, Jianhua Chang, Fangfang Lv, Xiaonan Hong, Huijie Wang, Jialei Wang, Xinmin Zhao, Xianghua Wu…
    Citation: BMC Cancer 2017 17:188
    Content type: Research article Published on:

  20. Lung cancer is the most common cause of cancer related death worldwide. The majority of cases are detected at a late stage when prognosis is poor. The EarlyCDT®-Lung Test detects autoantibodies to abnormal cel...

    Authors: F. M. Sullivan, Eoghan Farmer, Frances S. Mair, Shaun Treweek, Denise Kendrick, Cathy Jackson, Chris Robertson, Andrew Briggs, Colin McCowan, Laura Bedford, Ben Young, Kavita Vedhara, Stephanie Gallant, Roberta Littleford, John Robertson, Herb Sewell…
    Citation: BMC Cancer 2017 17:187
    Content type: Study protocol Published on:

  21. Approximately one third of cancer survivors in the United Kingdom face ongoing and debilitating psychological and physical symptoms related to poor quality of life. Very little is known about current post-canc...

    Authors: M. Duncan, J. Deane, P. D. White, D. Ridge, R. Roylance, A. Korszun, T. Chalder, K. S. Bhui, M. A. Thaha and L. Bourke
    Citation: BMC Cancer 2017 17:186
    Content type: Research article Published on:

  22. The purpose of this retrospective study was to determine whether RFA could provide an alternative treatment modality for selected patients who are not candidates for hepatic resection.

    Authors: Jin Won Lee, Moon Hyung Choi, Young Joon Lee, Bandar Ali, Han Mo Yoo, Kyo Young Song and Cho Hyun Park
    Citation: BMC Cancer 2017 17:185
    Content type: Research article Published on:

  23. Most cancer deaths result from tumor cells that have metastasized beyond their tissue of origin, or have developed drug resistance. Across many cancer types, patients with advanced stage disease would benefit ...

    Authors: Cai M. Roberts, Sophia A. Shahin, Joana Loeza, Thanh H. Dellinger, John C. Williams and Carlotta A. Glackin
    Citation: BMC Cancer 2017 17:184
    Content type: Research article Published on:

  24. Chronic Helicobacter pylori infection plays a central role in the development of gastric cancer as shown by biological and epidemiological studies. The H. pylori antibody and serum pepsinogen (PG) tests have been...

    Authors: Chisato Hamashima, Shizuka Sasazuki, Manami Inoue and Shoichiro Tsugane
    Citation: BMC Cancer 2017 17:183
    Content type: Research article Published on:

  25. In this era of oxaliplatin-based adjuvant therapy, the optimal sequence in which chemoradiotherapy should be administered for pathological stage N2 rectal cancer is unknown. The aim of this study was to invest...

    Authors: Yan-Ru Feng, Jing Jin, Hua Ren, Xin Wang, Shu-Lian Wang, Wei-Hu Wang, Yong-Wen Song, Yue-Ping Liu, Yuan Tang, Ning Li, Xin-Fan Liu, Hui Fang, Zi-Hao Yu and Ye-Xiong Li
    Citation: BMC Cancer 2017 17:182
    Content type: Research article Published on:

  26. A shift towards less burdening and more patient friendly treatments for breast cancer is currently ongoing. In low-risk patients with early-stage disease, accelerated partial breast irradiation (APBI) is an al...

    Authors: R. K. Charaghvandi, B. van Asselen, M. E. P. Philippens, H. M. Verkooijen, C. H. van Gils, P. J. van Diest, R. M. Pijnappel, M. G. G. Hobbelink, A. J. Witkamp, T. van Dalen, E. van der Wall, T. C. van Heijst, R. Koelemij, M. van Vulpen and H. J. G. D. van den Bongard
    Citation: BMC Cancer 2017 17:181
    Content type: Study protocol Published on:

  27. This paper describes the multi-institutional prospective phase II clinical trial, SPARK: Stereotactic Prostate Adaptive Radiotherapy utilizing Kilovoltage Intrafraction Monitoring (KIM). KIM is a real-time image ...

    Authors: Paul Keall, Doan Trang Nguyen, Ricky O’Brien, Jeremy Booth, Peter Greer, Per Poulsen, Val Gebski, Andrew Kneebone and Jarad Martin
    Citation: BMC Cancer 2017 17:180
    Content type: Study protocol Published on:

  28. Virtually all prostate cancer deaths occur due to obtaining the castration-resistant phenotype after prostate cancer cells escaped from apoptosis and/or growth suppression initially induced by androgen recepto...

    Authors: Linjie Chen, Dennis W. Wolff, Yan Xie, Ming-Fong Lin and Yaping Tu
    Citation: BMC Cancer 2017 17:179
    Content type: Research article Published on:

  29. Glioblastoma is the most frequent and most malignant brain tumor with the patients having a median survival of only 14.6 months. Although glioblastoma patients are treated with surgery, radiation and chemother...

    Authors: Stine S. Jensen, Stine A. Petterson, Bo Halle, Charlotte Aaberg-Jessen and Bjarne W. Kristensen
    Citation: BMC Cancer 2017 17:178
    Content type: Research article Published on:

  30. We previously showed that 1-methylnicotinamide (1-MNA) and its analog 1,4-dimethylpyridine (1,4-DMP) could inhibit the formation of lung metastases and enhance the efficacy of cyclophosphamide-based chemothera...

    Authors: Agnieszka Denslow, Marta Switalska, Marcin Nowak, Magdalena Maciejewska, Stefan Chlopicki, Andrzej Marcinek, Jerzy Gebicki and Joanna Wietrzyk
    Citation: BMC Cancer 2017 17:177
    Content type: Research article Published on:

  31. Myeloid ecotropic viral integration site 1 (MEIS1) protein plays a synergistic causative role in acute myeloid leukemia (AML). However, MEIS1 has also shown to be a potential tumor suppressor in some other can...

    Authors: Jie Zhu, Liang Cui, Axiang Xu, Xiaotao Yin, Fanglong Li and Jiangping Gao
    Citation: BMC Cancer 2017 17:176
    Content type: Research article Published on:

  32. Our previous study showed that GATA6 plays important roles in cholangiocarcinoma (CCA) cell invasion and metastasis. However, the regulation mechanism of GATA6 in CCA is not clear. In this study, we studied th...

    Authors: Feng Tian, Jian Chen, Shuguo Zheng, Dajiang Li, Xin Zhao, Peng Jiang, Jianwei Li and Shuguang Wang
    Citation: BMC Cancer 2017 17:175
    Content type: Research article Published on:

  33. Unperturbed tumor growth kinetics is one of the more studied cancer topics; however, it is poorly understood. Mathematical modeling is a useful tool to elucidate new mechanisms involved in tumor growth kinetic...

    Authors: Maraelys Morales González, Javier Antonio González Joa, Luis Enrique Bergues Cabrales, Ana Elisa Bergues Pupo, Baruch Schneider, Suleyman Kondakci, Héctor Manuel Camué Ciria, Juan Bory Reyes, Manuel Verdecia Jarque, Miguel Angel O’Farril Mateus, Tamara Rubio González, Soraida Candida Acosta Brooks, José Luis Hernández Cáceres and Gustavo Victoriano Sierra González
    Citation: BMC Cancer 2017 17:174
    Content type: Research article Published on:

  34. The RAS/RAF/MEK/ERK pathway is constitutively activated in many cancers. Selumetinib (AZD6244, ARRY-142886) is an oral, potent and highly selective, allosteric MEK1/2 inhibitor with a short half-life that has ...

    Authors: Patricia M. LoRusso, Jeffrey R. Infante, Kevin B. Kim, Howard A. Burris III, Gregory Curt, Ugochi Emeribe, Delyth Clemett, Helen K. Tomkinson and Roger B. Cohen
    Citation: BMC Cancer 2017 17:173
    Content type: Research article Published on:

  35. Approximately 250 million people worldwide are chronically infected with hepatitis B virus (HBV) and more than half of the hepatocellular carcinoma (HCC) cases are attributed to this infection. As HCC has a hi...

    Authors: Jeffery Fairman, Katherine H. Liu and Stephan Menne
    Citation: BMC Cancer 2017 17:172
    Content type: Research article Published on:

  36. The preoperative C-reactive protein/Albumin (CRP/Alb) ratio has been shown to be valuable in predicting the prognosis of patients with certain cancers. The aim of our study is to explore its prognostic value i...

    Authors: Shengjie Guo, Xiaobo He, Qian Chen, Guangwei Yang, Kai Yao, Pei Dong, Yunlin Ye, Dong Chen, Zhiling Zhang, Zike Qin, Zhuowei Liu, Yunfei Xue, Meng Zhang, Ruiwu Liu, Fangjian Zhou and Hui Han
    Citation: BMC Cancer 2017 17:171
    Content type: Research article Published on:

  37. Loss of CBX7 expression has been described in several malignant neoplasias, including human colon and thyroid carcinomas proposing CBX7 as a tumor suppressor gene with a key role in cancer progression. This role ...

    Authors: Floriana Forzati, Marco De Martino, Francesco Esposito, Romina Sepe, Simona Pellecchia, Umberto Malapelle, Gianluca Pellino, Claudio Arra and Alfredo Fusco
    Citation: BMC Cancer 2017 17:170
    Content type: Research article Published on:

  38. Human triple-negative breast cancer has limited therapeutic choices. Breast tumor cells have depolarized plasma membrane potential. Using this unique electrical property, we aim to develop an effective selecti...

    Authors: Han-Gang Yu, Sarah McLaughlin, Mackenzie Newman, Kathleen Brundage, Amanda Ammer, Karen Martin and James Coad
    Citation: BMC Cancer 2017 17:169
    Content type: Research article Published on:

  39. Principal Treatment Centres (PTC) were established to provide age-appropriate care as well as clinical expertise for children and young people with cancer. However, little is known about the effects of special...

    Authors: Lesley Fairley, Daniel P. Stark, Daniel Yeomanson, Sally E. Kinsey, Adam W. Glaser, Susan V. Picton, Linda Evans and Richard G. Feltbower
    Citation: BMC Cancer 2017 17:168
    Content type: Research article Published on:

  40. Recently studies have demonstrated that the long non-coding RNA (lncRNA) metastasis associated lung adenocarcinoma transcript 1 (MALAT1) may participate in the development and progression of lung cancer. In th...

    Authors: Jian-Zhong Wang, Jing-Jun Xiang, Li-Ge Wu, Yan-Sen Bai, Zhuo-Wang Chen, Xiang-Qian Yin, Qing Wang, Wen-Hao Guo, Ying Peng, Huan Guo and Ping Xu
    Citation: BMC Cancer 2017 17:167
    Content type: Research article Published on:

  41. Cancer-related fatigue (CRF) and insomnia are major complaints in breast cancer survivors (BC). Aerobic training (AT), the standard therapy for CRF in BC, shows only minor to moderate treatment effects. Other ...

    Authors: Matthias Kröz, Marcus Reif, Augustina Glinz, Bettina Berger, Andreas Nikolaou, Roland Zerm, Benno Brinkhaus, Matthias Girke, Arndt Büssing and Christoph Gutenbrunner
    Citation: BMC Cancer 2017 17:166
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Cancer 2020 20:1174

  42. Links between participating in unhealthy behaviours, e.g. smoking, and an increased risk of developing some cancers are well established. Unemployed adults are more likely to participate in cancer-related heal...

    Authors: Catherine H. Stewart, Philip Berry, Dunja Przulj and Charlene Treanor
    Citation: BMC Cancer 2017 17:165
    Content type: Research article Published on:

  43. Dysregulated WNT signaling dominates adrenocortical malignancies. This study investigates whether silencing of the WNT negative regulator DKK3 (Dickkopf-related protein 3), an implicated adrenocortical differe...

    Authors: Joyce Y. Cheng, Taylor C. Brown, Timothy D. Murtha, Adam Stenman, C. Christofer Juhlin, Catharina Larsson, James M. Healy, Manju L. Prasad, Wolfram T. Knoefel, Andreas Krieg, Ute I. Scholl, Reju Korah and Tobias Carling
    Citation: BMC Cancer 2017 17:164
    Content type: Research article Published on:

  44. Docetaxel based therapy is one of the first line chemotherapeutic agents for the treatment of metastatic castrate-resistant prostate cancer. However, one of the major obstacles in the treatment of these patien...

    Authors: D. J. Lundon, A. Boland, M. Prencipe, G. Hurley, A O’Neill, E. Kay, S. T. Aherne, P. Doolan, S. F. Madden, M. Clynes, C. Morrissey, J. M. Fitzpatrick and R. W. Watson
    Citation: BMC Cancer 2017 17:163
    Content type: Research article Published on:

  46. Metallothionein 1H (MT1H) expression level is downregulated in several kinds of tumors, including hepatocellular cancer (HCC). However, its biological functions and underlying mechanisms in HCC is largely unknown...

    Authors: Yulong Zheng, Lihua Jiang, Yongxian Hu, Cheng Xiao, Nong Xu, Jianying Zhou and Xinhui Zhou
    Citation: BMC Cancer 2017 17:161
    Content type: Research article Published on:

  47. In metastatic breast cancer, the status of the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2), as well as the Ki-67 index sometimes change between prima...

    Authors: Hitoshi Inari, Nobuyasu Suganuma, Kae Kawachi, Tatsuya Yoshida, Takashi Yamanaka, Yoshiyasu Nakamura, Mitsuyo Yoshihara, Hirotaka Nakayama, Ayumi Yamanaka, Katsuhiko Masudo, Takashi Oshima, Tomoyuki Yokose, Yasushi Rino, Satoru Shimizu, Yohei Miyagi and Munetaka Masuda
    Citation: BMC Cancer 2017 17:160
    Content type: Research article Published on:

  48. We set out to estimate net survival trends for 10 common cancers in 279 cancer registry populations in 67 countries around the world, as part of the CONCORD-2 study. Net survival can be interpreted as the prop...

    Authors: Devon Spika, Finian Bannon, Audrey Bonaventure, Laura M Woods, Rhea Harewood, Helena Carreira, Michel P Coleman and Claudia Allemani
    Citation: BMC Cancer 2017 17:159
    Content type: Research article Published on:

  49. TSPYL5, a putative tumor suppressor gene, belongs to the nucleosome assembly protein family. The chromosomal location of the TSPYL5 gene is 8Q22.1, and its exact role in prostate cancer etiology remains unclear. ...

    Authors: Senthil R. Kumar, Jeffrey N. Bryan, Magda Esebua, James Amos-Landgraf and Tanner J. May
    Citation: BMC Cancer 2017 17:158
    Content type: Research article Published on:

  50. Neuroblastoma (NB), a tumor of the primitive neural crest, despite aggressive treatment portends a poor long-term survival for patients with advanced high stage NB. New treatment strategies are required.

    Authors: Reza Bayat Mokhtari, Narges Baluch, Micky Ka Hon Tsui, Sushil Kumar, Tina S. Homayouni, Karen Aitken, Bikul Das, Sylvain Baruchel and Herman Yeger
    Citation: BMC Cancer 2017 17:156
    Content type: Research article Published on:

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