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Articles

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  1. The study aimed to investigate the clinical features and prognosis factors of adult patients with Langerhans cell histiocytosis (LCH) with pulmonary involvement, especially multisystem (MS) LCH with pulmonary ...

    Authors: Hui-lei Miao, Ai-lin Zhao, Ming-hui Duan, Dao-bin Zhou, Xin-xin Cao and Jian Li
    Citation: BMC Cancer 2020 20:911
  2. The prognosis of lung cancer was found to be associated with a series of biomarkers related to the tumor immune microenvironment (TIME), which can modulate the biological behaviors and consequent outcomes of l...

    Authors: Dantong Sun, Lu Tian, Tiantian Bian, Han Zhao, Junyan Tao, Lizong Feng, Qiaoling Liu and Helei Hou
    Citation: BMC Cancer 2020 20:910
  3. Mucinous adenocarcinoma (MC) is the second most common pathological type of colon carcinoma (CC). Colon cancer liver metastases (CLMs) are common and lethal, and complete resection of the primary tumour and me...

    Authors: Jia Huang, Guodong Chen, Huan Liu, Yiwei Zhang, Rong Tang, Qiulin Huang, Kai Fu, Xiuda Peng and Shuai Xiao
    Citation: BMC Cancer 2020 20:908
  4. Pancreatic neuroendocrine neoplasms (p-NENs) are a group of highly heterogeneous tumors with distinct clinicopathological features and long-term prognosis. In 2017, in order to better stratify patients into pr...

    Authors: Min Yang, Lin Zeng, Neng-wen Ke, Chun-lu Tan, Bo-le Tian, Xu-bao Liu, Bo Xiang and Yi Zhang
    Citation: BMC Cancer 2020 20:906
  5. A low level of methylation at cg05575921 in the aryl-hydrocarbon receptor repressor (AHRR) gene is robustly associated with smoking, and some studies have observed associations between cg05575921 methylation and ...

    Authors: Laurie Grieshober, Stefan Graw, Matt J. Barnett, Mark D. Thornquist, Gary E. Goodman, Chu Chen, Devin C. Koestler, Carmen J. Marsit and Jennifer A. Doherty
    Citation: BMC Cancer 2020 20:905
  6. This case-control study investigated the role of Chlamydia pneumoniae (Cpn) infection in the pathogenesis of lung cancer and the combined and interaction effect of Cpn infection, smoking, and various environmenta...

    Authors: Xin Xu, Zhiqiang Liu, Weimin Xiong, Minglian Qiu, Shuling Kang, Qiuping Xu, Lin Cai and Fei He
    Citation: BMC Cancer 2020 20:903
  7. High resolution melting curve analysis is a cost-effective rapid screening method for detection of somatic gene mutation. The performance characteristics of this technique has been explored previously, however...

    Authors: Reenu Anne Joy, Sukrishna Kamalasanan Thelakkattusserry, Narendranath Vikkath, Renjitha Bhaskaran, Sajitha Krishnan, Damodaran Vasudevan and Prasanth S. Ariyannur
    Citation: BMC Cancer 2020 20:902
  8. Since the development of three-dimensional conformal radiotherapy and intensity-modulated radiotherapy (IMRT), no prospective study has investigated whether concurrent chemoradiotherapy (SIB-IMRT with 60 Gy) r...

    Authors: Lin-rui Gao, Xin Wang, Weiming Han, Wei Deng, Chen Li, Xiaomin Wang, Yidian Zhao, Wenjie Ni, Xiao Chang, Zongmei Zhou, Lei Deng, Wenqing Wang, Wenyang Liu, Jun Liang, Tao Zhang, Nan Bi…
    Citation: BMC Cancer 2020 20:901
  9. The association of neutrophil-lymphocyte ratio (NLR) and CD34 expression level with PSA level, Gleason score, and clinical stage was investigated in patients with prostate cancer. The correlation between NLR a...

    Authors: Yiyang Wang, Xiaofei Dong, Zhaokui Qu, Kang Peng, Xiaolei Sun and Renfu Chen
    Citation: BMC Cancer 2020 20:900
  10. Art therapy may improve the physical, mental, and emotional wellbeing of individuals for a variety of purposes. It remains understudied and underutilized in cancer care. We sought to determine the ability of a...

    Authors: E. B. Elimimian, L. Elson, E. Stone, R. S. Butler, M. Doll, S. Roshon, C. Kondaki, A. Padgett and Z. A. Nahleh
    Citation: BMC Cancer 2020 20:899

    The Correction to this article has been published in BMC Cancer 2020 20:1125

  11. Adolescent and young adult (AYA) childhood cancer survivors (CCS) should be empowered to continue their survivor-focused care as they transition into adult medicine. However, the majority of AYA-aged survivors...

    Authors: Karim Thomas Sadak, Milki T. Gemeda, Michelle Grafelman, Joseph P. Neglia, David R. Freyer, Eileen Harwood and Jude Mikal
    Citation: BMC Cancer 2020 20:898
  12. There are controversial results concerning the prognostic implication of TERT promoter mutation in glioma patients concerning MGMT status. In this meta-analysis, we investigated whether there are any interactions...

    Authors: Huy Gia Vuong, Thu Quynh Nguyen, Tam N. M. Ngo, Hoang Cong Nguyen, Kar-Ming Fung and Ian F. Dunn
    Citation: BMC Cancer 2020 20:897
  13. Anticancer compound 3-bromopyruvate (3-BrPA) suppresses cancer cell growth via targeting glycolytic and mitochondrial metabolism. The malignant peripheral nerve sheath tumor (MPNST), a very aggressive, therapy...

    Authors: Christian Linke, Markus Wösle and Anja Harder
    Citation: BMC Cancer 2020 20:896
  14. Increased fucosylation is associated with the chemoresistance phenotype. Meanwhile, fucosyltransferase IV (FUT4) amounts are frequently elevated in lung cancer and may be related to increased chemoresistance.

    Authors: Wei Gao, Jinxiao Liang, Yiru Ye, Jinlan Lu, Tongtong Lin, Na Wang, Jingyin Dong and Jianping Pan
    Citation: BMC Cancer 2020 20:895
  15. The effect of brachytherapy on lymphocytes and cytokines in the tumor microenvironment is unclear. This study aimed to analyze the relationship between the invasion of lymphocytes and cytokines in the tumor mi...

    Authors: Lin Li, Hong Cheng Yue, Yun Wei Han, Wei Liu, Liang Geng Xiong and Jian Wen Zhang
    Citation: BMC Cancer 2020 20:893
  16. The global incidence of thyroid cancer (TC) has risen considerably during the last three decades, while prognosis is generally favorable. We assessed the long-term all-cause mortality in TC survivors compared ...

    Authors: Elena Izkhakov, Lital Keinan-Boker, Micha Barchana, Yacov Shacham, Iris Yaish, Narin N. Carmel Neiderman, Dan M. Fliss, Naftali Stern and Joseph Meyerovitch
    Citation: BMC Cancer 2020 20:892
  17. We have previously found there was a small subpopulation of cells with cancer stem cell-like phenotype ALDH-1 in cervical cancer. Radiotherapy has been applied in most of the cervical cancer. However,the mecha...

    Authors: Tingting Yao, Xueling Weng, Yao Yao, Chunxian Huang, Jing Li, Yongpai Peng, Rongchun Lin and Zhongqiu Lin
    Citation: BMC Cancer 2020 20:891
  18. Extremity liposarcoma represents 25% of extremity soft tissue sarcoma and has a better prognosis than liposarcoma occurring in other anatomic sites. The purpose of this study was to develop two nomograms for p...

    Authors: Lin Ye, Chuan Hu, Cailin Wang, Weiyang Yu, Feijun Liu and Zhenzhong Chen
    Citation: BMC Cancer 2020 20:889
  19. There is growing evidence that pseudogenes may serve as prognostic biomarkers in several cancers. The present study was designed to develop and validate an accurate and robust pseudogene pairs-based signature ...

    Authors: Yajuan Du and Ying Gao
    Citation: BMC Cancer 2020 20:887
  20. Despite obvious advances over the last decades, locally advanced adenocarcinomas of the gastroesophageal junction (GEJ) still carry a dismal prognosis with overall 5-year survival rates of less than 50% even w...

    Authors: Sylvie Lorenzen, Alexander Biederstädt, Ulrich Ronellenfitsch, Christoph Reißfelder, Stefan Mönig, Frederik Wenz, Claudia Pauligk, Martin Walker, Salah-Eddin Al-Batran, Bernhard Haller and Ralf-Dieter Hofheinz
    Citation: BMC Cancer 2020 20:886
  21. Identifying and tracking somatic mutations in cell-free DNA (cfDNA) by next-generation sequencing (NGS) has the potential to transform the clinical management of subjects with advanced non-small cell lung canc...

    Authors: John Jiang, Hans-Peter Adams, Maria Lange, Sandra Siemann, Mirjam Feldkamp, Sylvie McNamara, Sebastian Froehler, Stephanie J. Yaung, Lijing Yao, Aarthi Balasubramanyam, Nalin Tikoo, Christine Ju, H. Jost Achenbach, Rainer Krügel and John F. Palma
    Citation: BMC Cancer 2020 20:885
  22. In recent years, there is increasing evidence showing a beneficial outcome (e.g. progression free survival; PFS) after metastases-directed therapy (MDT) with external beam radiotherapy (EBRT) or targeted surge...

    Authors: Bastiaan M. Privé, Marcel J. R. Janssen, Inge M. van Oort, Constantijn H. J. Muselaers, Marianne A. Jonker, Michel de Groot, Niven Mehra, J. Fred Verzijlbergen, Tom W. J. Scheenen, Patrik Zámecnik, Jelle O. Barentsz, Martin Gotthardt, Walter Noordzij, Wouter V. Vogel, Andries M. Bergman, Henk G. van der Poel…
    Citation: BMC Cancer 2020 20:884

    The Update to this article has been published in Trials 2021 22:768

  23. Myxoid liposarcoma (MLS) has the tendency to metastasize extrapulmonary. Although prognostic factors at the initial diagnosis of MLS have been reported, those at diagnosis of metastasis remain unclear. The pur...

    Authors: Yusuke Shinoda, Eisuke Kobayashi, Hiroshi Kobayashi, Tomoaki Mori, Naofumi Asano, Robert Nakayama, Hideo Morioka, Shintaro Iwata, Tsukasa Yonemoto, Takeshi Ishii, Tohru Hiruma, Akira Kawai and Hirotaka Kawano
    Citation: BMC Cancer 2020 20:883
  24. Cytotoxic chemotherapy can cure advanced germ cell tumors. Nevertheless, cancer treatment may induce cellular senescence and accelerate molecular aging. The aging process implies an increase of cells expressing p...

    Authors: Maria T. Bourlon, Hugo E. Velazquez, Juan Hinojosa, Luis Orozco, Ricardo Rios-Corzo, Guadalupe Lima, Luis Llorente, Diego F. Hernandez-Ramirez, Francisco J. Valentin-Cortez, Irene Medina-Rangel and Yemil Atisha-Fregoso
    Citation: BMC Cancer 2020 20:882
  25. A. oxyphylla extract is known to possess a wide range of pharmacological activites. However, the molecular mechanism of A. oxyphylla and its bioactive compound nootkatone in colorectal cancer is unknown.

    Authors: Eunsu Yoo, Jaehak Lee, Pattawika Lertpatipanpong, Junsun Ryu, Chong-Tai Kim, Eul-Yong Park and Seung Joon Baek
    Citation: BMC Cancer 2020 20:881
  26. Tobacco smoking is associated with a unique mutational signature in the human cancer genome. It is unclear whether tobacco smoking-altered DNA methylations and gene expressions affect smoking-related mutationa...

    Authors: Zhishan Chen, Wanqing Wen, Qiuyin Cai, Jirong Long, Ying Wang, Weiqiang Lin, Xiao-ou Shu, Wei Zheng and Xingyi Guo
    Citation: BMC Cancer 2020 20:880
  27. The nicotinamide nucleotide transhydrogenase antisense RNA 1 (NNT-AS1) is a long non-coding RNA aberrantly expressed in human malignancies. We aimed to analyze available data to evaluate the correlation betwee...

    Authors: Chenghao Zhang, Xiaolei Ren, Zhongyue Liu and Chao Tu
    Citation: BMC Cancer 2020 20:879
  28. Triple-negative breast cancer (TNBC) patients have relatively poor clinical outcomes. A marker predicting the prognosis of patients with TNBC could help guide treatment. Extensive evidence demonstrates that an...

    Authors: Yu-Chen Cai, Hang Yang, Ke-Feng Wang, Tan-Huan Chen, Wen-Qi Jiang and Yan-Xia Shi
    Citation: BMC Cancer 2020 20:878
  29. Currently, adjuvant therapy is not recommended for patients with thoracic esophageal squamous cell cancer (TESCC) after radical surgery, and a proportion of these patients go on to develop locoregional recurre...

    Authors: Xiao Chang, Lei Deng, Wenjie Ni, Chen Li, Weiming Han, Lin-rui Gao, Shijia Wang, Zongmei Zhou, Dongfu Chen, Qinfu Feng, Jun Liang, Nan Bi, Jima Lv, Shugeng Gao, Yousheng Mao, Qi Xue…
    Citation: BMC Cancer 2020 20:877
  30. Some evidence has shown that malignant breast tumours have lower electrical impedance than surrounding normal tissues. Electrical impedance could be used as an indicator for breast cancer detection. The purpos...

    Authors: Blanca Murillo-Ortiz, Abraham Hernández-Ramírez, Talia Rivera-Villanueva, David Suárez-García, Mario Murguía-Pérez, Sandra Martínez-Garza, Allyson Rodríguez-Penin, Rosario Romero-Coripuna and Xiomara Midory López-Partida
    Citation: BMC Cancer 2020 20:876
  31. The treatment of choice for advanced non–small cell lung cancer is selected according to the presence of specific alterations. Patients should undergo molecular testing for relevant modifications and the mutat...

    Authors: Luciene Schluckebier, Rosangela Caetano, Osvaldo Ulises Garay, Giuliana T. Montenegro, Marcelo Custodio, Veronica Aran and Carlos Gil Ferreira
    Citation: BMC Cancer 2020 20:875
  32. Langerhans cell histiocytosis (LCH) affects 1–2 in 1,000,000 people. The disease is not associated with increased risk of treatment failure (especially among older children), but appropriate procedures impleme...

    Authors: Anna Raciborska, Katarzyna Bilska, Jadwiga Węcławek-Tompol, Olga Gryniewicz-Kwiatkowska, Małgorzata Hnatko-Kołacz, Joanna Stefanowicz, Anna Pieczonka, Katarzyna Jankowska, Filip Pierelejewski, Tomasz Ociepa, Grażyna Sobol-Milejska, Katarzyna Muszyńska-Rosłan, Olga Michoń, Wanda Badowska, Monika Radwańska and Katarzyna Drabko
    Citation: BMC Cancer 2020 20:874
  33. Recent studies have shown that chemotherapy destabilizes the blood vasculature and increases circulating tumor cell (CTC) influx into the circulation of metastatic cancer patients (Met-pa). CTCs are a precurso...

    Authors: Nerymar Ortiz-Otero, Jocelyn R. Marshall, Bradley Lash and Michael R. King
    Citation: BMC Cancer 2020 20:873
  34. 5α-reductase inhibitors (5-ARIs) inhibit the pathway of converting the testosterone to dihydrotestosterone and are widely used in benign prostatic hyperplasia patients. Since androgen receptor activation may p...

    Authors: Chien-Sheng Wang, Ching-Chia Li, Yung-Shun Juan, Wen-Jeng Wu and Hsiang-Ying Lee
    Citation: BMC Cancer 2020 20:872
  35. Non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin and sulindac are effective for colorectal cancer prevention in humans and some animal models, but concerns over gastro-intestinal (GI) ulceration ...

    Authors: Jennifer S. Davis, Preeti Kanikarla-Marie, Mihai Gagea, Patrick L. Yu, Dexing Fang, Manu Sebastian, Peiying Yang, Ernest Hawk, Roderick Dashwood, Lenard M. Lichtenberger, David Menter and Scott Kopetz
    Citation: BMC Cancer 2020 20:871
  36. BRAF-activated noncoding RNA (BANCR) is aberrantly expressed in various tumor tissues and has been confirmed to function as a tumor suppressor or oncogene in many types of cancers. Considering the conflicting ...

    Authors: Shixu Fang, Zhou Liu, Qiang Guo, Cheng Chen, Xixian Ke and Gang Xu
    Citation: BMC Cancer 2020 20:870
  37. Indoleamine 2, 3-dioxygenase-1 (IDO1) is a promising target for immunotherapy in bladder cancer (BC). IDO1 breaks-down tryptophan to generate kynurenine derivatives, which may activate the aryl hydrocarbon rec...

    Authors: Luiz Henrique Gomes Matheus, Stephanie Vanin Dalmazzo, Rodrigo Barbosa Oliveira Brito, Lucas Alves Pereira, Robson José de Almeida, Cleber Pinto Camacho and Humberto Dellê
    Citation: BMC Cancer 2020 20:869
  38. The standard chemotherapy regimens for soft tissue sarcoma are doxorubicin-based. This retrospective study aimed to assess the efficacy and safety of pirarubicin, ifosfamide, and etoposide combination therapy ...

    Authors: Shiro Saito, Hisaki Aiba, Satoshi Yamada, Hideki Okamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Takanobu Otsuka and Hideki Murakami
    Citation: BMC Cancer 2020 20:868
  39. Terminal-stage solid tumors are one of the main causes of disseminated intravascular coagulation (DIC); effective therapeutic strategies are therefore warranted. This study aimed to investigate the association...

    Authors: Kohei Taniguchi, Hiroyuki Ohbe, Kazuma Yamakawa, Hiroki Matsui, Kiyohide Fushimi and Hideo Yasunaga
    Citation: BMC Cancer 2020 20:867
  40. An increasing number of studies have described the aberrant expression of homeobox (HOX) proteins in gastric cancer (GC), which is critically associated with the prognosis and clinicopathological characteristi...

    Authors: Xiao Jin, Lu Dai, Yilan Ma, Jiayan Wang, Haihao Yan, Ye Jin, Xiaojuan Zhu and Zheng Liu
    Citation: BMC Cancer 2020 20:866
  41. Melanoma has the highest mortality rate of all skin tumors, and metastases are the major cause of death from it. The molecular mechanism leading to melanoma metastasis is currently unclear.

    Authors: Wenxing Su, Yi Guan, Biao Huang, Juanjuan Wang, Yuqian Wei, Ying Zhao, Qingqing Jiao, Jiang Ji, Daojiang Yu and Longjiang Xu
    Citation: BMC Cancer 2020 20:863
  42. The aim of this study is to assess biplane transrectal ultrasonography (TRUS) plus ultrasonic elastosonography (UE) and contrast-enhanced ultrasonography (CEUS) in T staging of rectal cancer.

    Authors: Yanru Feng, Chanjuan Peng, Yuan Zhu and Luying Liu
    Citation: BMC Cancer 2020 20:862
  43. Breast Cancer (BC) is associated with inherited gene mutations. High throughput genotyping of BC samples has led to the identification and characterization of biomarkers for the diagnosis of BC. The most commo...

    Authors: Divya Bakshi, Ashna Nagpal, Varun Sharma, Indu Sharma, Ruchi Shah, Bhanu Sharma, Amrita Bhat, Sonali Verma, Gh. Rasool Bhat, Deepak Abrol, Rahul Sharma, Samantha Vaishnavi and Rakesh Kumar
    Citation: BMC Cancer 2020 20:861
  44. Worldwide cervical cancer is the third most common malignancy in women. It usually arises from the cervical area which is susceptible to Human Papilloma virus induced malignancy changes. In low-resource settin...

    Authors: Gebretsadik Hailemariam, Hailay Gebreyesus, Tewolde Wubayehu, Tsgehana Gebregyorgis, Kidanemariam Gebrecherkos, Mebrahtu Teweldemedhin and Manaye Kifle
    Citation: BMC Cancer 2020 20:858
  45. Endometrial cancer (EC) is the most common gynecologic cancer in women, and the incidence of EC has increased by about 1% per year in the U. S over the last 10 years. Although 5-year survival rates for early-s...

    Authors: Daniel G. Piqué, John M. Greally and Jessica C. Mar
    Citation: BMC Cancer 2020 20:857

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