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906 result(s) within Volume 17 of BMC Cancer

Page 10 of 19

  1. Hormonal therapy is used as a treatment option in high-grade ovarian carcinoma (HGOC), but the role and choice of treatment remains unclear. Agents used include tamoxifen and aromatase inhibitors. Our aim was ...

    Authors: Angela George, Jennifer McLachlan, Nina Tunariu, Chiara Della Pepa, Cristina Migali, Martin Gore, Stan Kaye and Susana Banerjee
    Citation: BMC Cancer 2017 17:456
    Content type: Research article Published on:

  3. The pathological and oncological outcomes of retro-pubic radical prostatectomy (RRP) and robot-assisted radical prostatectomy (RARP) have not been sufficiently investigated.

    Authors: Tetsuya Fujimura, Hiroshi Fukuhara, Satoru Taguchi, Yuta Yamada, Toru Sugihara, Tohru Nakagawa, Aya Niimi, Haruki Kume, Yasuhiko Igawa and Yukio Homma
    Citation: BMC Cancer 2017 17:454
    Content type: Research article Published on:

  4. We describe a randomized, non-blinded Phase II interventional study to assess the safety and efficacy of stereotactic ablative radiotherapy (SABR) for hormone-sensitive oligometastatic prostate adenocarcinoma,...

    Authors: Noura Radwan, Ryan Phillips, Ashley Ross, Steven P. Rowe, Michael A. Gorin, Emmanuel S. Antonarakis, Curtiland Deville, Stephen Greco, Samuel Denmeade, Channing Paller, Daniel Y. Song, Maximilian Diehn, Hao Wang, Michael Carducci, Kenneth J. Pienta, Martin G. Pomper…
    Citation: BMC Cancer 2017 17:453
    Content type: Study protocol Published on:

  6. Recognizing resistance or susceptibility to the current standard cisplatin and paclitaxel treatment could improve therapeutic outcomes of metastatic or recurrent cervical cancer.

    Authors: Sofia Karageorgopoulou, Ioannis D. Kostakis, Maria Gazouli, Sonia Markaki, Marios Papadimitriou, Evangelos Bournakis, Meletios-Athanassios Dimopoulos and Christos A Papadimitriou
    Citation: BMC Cancer 2017 17:451
    Content type: Research article Published on:

  7. Neoadjuvant chemoradiation is not recommended as an approach for treatment of esophageal squamous cell carcinoma due to its significant postoperative mortality. However, it is assumed the combination of neoadj...

    Authors: Han Tang, Lijie Tan, Yaxing Shen, Hao Wang, Miao Lin, Mingxiang Feng, Songtao Xu, Weigang Guo, Cheng Qian, Tianshu Liu, Zhaochong Zeng, Yingyong Hou, Zhentao Yu, Hongjing Jiang, Zhigang Li, Chun Chen…
    Citation: BMC Cancer 2017 17:450
    Content type: Study protocol Published on:

  8. Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies in China and is an exceptionally drug-resistant tumor with a 5-year survival rate less than 15%. Cisplatin is the most commonly ...

    Authors: Xinfang Yu, Wei Li, Zhenkun Xia, Li Xie, Xiaolong Ma, Qi Liang, Lijun Liu, Jian Wang, Xinmin Zhou, Yifeng Yang and Haidan Liu
    Citation: BMC Cancer 2017 17:449
    Content type: Research article Published on:

  9. Better surgical techniques, chemotherapy and biological therapy have improved survival in patients with colorectal cancer (CRC), most markedly in younger patients. About half of patients over 70 years receive ...

    Authors: C. M. Lund, K. K. Vistisen, C. Dehlendorff, F. Rønholt, J. S. Johansen and D. L. Nielsen
    Citation: BMC Cancer 2017 17:448
    Content type: Study protocol Published on:

  10. Epithelial to mesenchymal transition (EMT) is the process by which stationary epithelial cells transdifferentiate to mesenchymal cells with increased motility. EMT is integral in early stages of development an...

    Authors: Princy Parsana, Sarah R. Amend, James Hernandez, Kenneth J. Pienta and Alexis Battle
    Citation: BMC Cancer 2017 17:447
    Content type: Research article Published on:

  11. Cancer and cancer treatment coincide with substantial negative physical, psychological and psychosocial problems. Physical activity (PA) can positively affect the negative effects of cancer and cancer treatmen...

    Authors: R. H. J. Golsteijn, C. Bolman, E. Volders, D. A. Peels, H. de Vries and L. Lechner
    Citation: BMC Cancer 2017 17:446
    Content type: Study protocol Published on:

  12. Transoral videolaryngoscopic surgery (TOVS) was developed as a new distinct surgical procedure for hypopharyngeal cancer (HPC) and supraglottic cancer (SGC) staged at up to T3. However, long-term treatment out...

    Authors: Yorihisa Imanishi, Hiroyuki Ozawa, Koji Sakamoto, Ryoichi Fujii, Seiji Shigetomi, Noboru Habu, Kuninori Otsuka, Yoichiro Sato, Yoshihiro Watanabe, Mariko Sekimizu, Fumihiro Ito, Toshiki Tomita and Kaoru Ogawa
    Citation: BMC Cancer 2017 17:445
    Content type: Research article Published on:

  13. Patients with type 2 diabetes (T2D) are at increased risk for developing cancer. As approximately 8% of the world’s population is living with T2D, even a slight increase in cancer risk could result in an enorm...

    Authors: Dennis Schrijnders, Geertruida H. de Bock, Sebastiaan T. Houweling, Kornelis J. J. van Hateren, Klaas H. Groenier, Jeffrey A. Johnson, Henk J. G. Bilo, Nanne Kleefstra and Gijs W. D. Landman
    Citation: BMC Cancer 2017 17:444
    Content type: Study protocol Published on:

  15. Acute myeloid leukemia (AML) accounts for more than two thirds of leukemia during pregnancy and has an incidence of 1 in 75,000 to 100,000. Its clinical management remains a challenging therapeutic task both f...

    Authors: Nicola Stefano Fracchiolla, Mariarita Sciumè, Francesco Dambrosi, Francesca Guidotti, Manuela Wally Ossola, Giovanna Chidini, Umberto Gianelli, Daniela Merlo and Agostino Cortelezzi
    Citation: BMC Cancer 2017 17:442
    Content type: Research article Published on:

  16. The Hippo pathway plays a vital role in liver regeneration and development by determining cellular lineage and regulating cell proliferation and apoptosis. In this study, we aimed to assess the role of the Hip...

    Authors: KyuHo Lee, Kyoung-Bun Lee, Hae Yoen Jung, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Suh and Ja-June Jang
    Citation: BMC Cancer 2017 17:441
    Content type: Research article Published on:

  17. As cancer metastasis is the deadliest aspect of cancer, causing 90% of human deaths, evaluating the molecular mechanisms underlying this process is the major interest to those in the drug development field. Bo...

    Authors: Shih-Hsin Tu, Yi-Chen Hsieh, Li-Chi Huang, Chun-Yu Lin, Kai-Wen Hsu, Wen-Shyang Hsieh, Wei-Ming Chi and Chia-Hwa Lee
    Citation: BMC Cancer 2017 17:440
    Content type: Research article Published on:

  18. Central nervous system tumours constitute 25% of all childhood cancers; more than half are located in the posterior fossa and surgery is usually part of therapy. One of the most disabling late effects of poste...

    Authors: Morten Wibroe, Johan Cappelen, Charlotte Castor, Niels Clausen, Pernilla Grillner, Thora Gudrunardottir, Ramneek Gupta, Bengt Gustavsson, Mats Heyman, Stefan Holm, Atte Karppinen, Camilla Klausen, Tuula Lönnqvist, René Mathiasen, Pelle Nilsson, Karsten Nysom…
    Citation: BMC Cancer 2017 17:439
    Content type: Study protocol Published on:

  19. Identification of BRCA mutations in breast cancer (BC) patients influences treatment and survival and may be of importance for their relatives. Testing is often restricted to women fulfilling high-risk criteria. ...

    Authors: Eli Marie Grindedal, Cecilie Heramb, Inga Karsrud, Sarah Louise Ariansen, Lovise Mæhle, Dag Erik Undlien, Jan Norum and Ellen Schlichting
    Citation: BMC Cancer 2017 17:438
    Content type: Research article Published on:

  20. To evaluate a new UGT1A and DPYD polymorphism panel to better predict irinotecan-induced toxicity and the clinical response in Chinese patients with metastatic colorectal cancer (mCRC).

    Authors: Dan Liu, Jian Li, Jing Gao, Yanyan Li, Rui Yang and Lin Shen
    Citation: BMC Cancer 2017 17:437
    Content type: Research article Published on:

  21. Solitary metastasis of a malignancy to the spleen is rare, particularly for gastric cancer. Only a few case reports have documented isolated splenic metastasis from early gastric cancer. We describe a case of ...

    Authors: Junichi Yoshizawa, Naoki Kubo, Satoshi Ishizone, Fumitoshi Karasawa and Ataru Nakayama
    Citation: BMC Cancer 2017 17:436
    Content type: Case report Published on:

  22. Limited national information is available in Morocco on the prevalence and distribution of HPV-sub-types of cervical cancer and the role of other risk factors. The aim was to determine the frequency of HPV-sub...

    Authors: Mohamed Berraho, Afaf Amarti-Riffi, Mohammed El-Mzibri, Rachid Bezad, Noureddine Benjaafar, Abdelatif Benideer, Noureddine Matar, Zinab Qmichou, Naima Abda, Mohammed Attaleb, Kaoutar Znati, Hind El Fatemi, Karima Bendahhou, Majdouline Obtel, Abdelhai Filali Adib, Simone Mathoulin-Pelissier…
    Citation: BMC Cancer 2017 17:435
    Content type: Research article Published on:

  23. Retinoblastoma (Rb) is the most common primary intraocular tumor in children. Local treatment of the intraocular disease is usually effective if diagnosed early; however advanced Rb can metastasize through rou...

    Authors: Anderson H. Webb, Bradley T. Gao, Zachary K. Goldsmith, Andrew S. Irvine, Nabil Saleh, Ryan P. Lee, Justin B. Lendermon, Rajini Bheemreddy, Qiuhua Zhang, Rachel C. Brennan, Dianna Johnson, Jena J. Steinle, Matthew W. Wilson and Vanessa M. Morales-Tirado
    Citation: BMC Cancer 2017 17:434
    Content type: Research article Published on:

  24. There are two lymphatic flows in lower rectal cancer; one along the inferior mesenteric artery and another towards the internal iliac artery. The benefit of dissection of lateral pelvic (LP) lymph nodes (LPLN)...

    Authors: Shigehiro Yanagita, Yoshikazu Uenosono, Takaaki Arigami, Yoshiaki Kita, Shinichiro Mori and Shoji Natsugoe
    Citation: BMC Cancer 2017 17:433
    Content type: Research article Published on:

  25. The protein kinase C (PKC) family comprises central regulators of multiple signal transduction processes and is involved in the progression of many cancers. Nuclear factor Kappa-B (NF-κB) is constitutively exp...

    Authors: Jin Zheng, Chuize Kong, Xiaoxi Yang, Xiaolu Cui, Xuyong Lin and Zhe Zhang
    Citation: BMC Cancer 2017 17:432
    Content type: Research article Published on:

  26. P21-activated kinase 1 (PAK1) stimulates growth and metastasis of colorectal cancer (CRC) through activation of multiple signalling pathways. Up-regulation of CRC stem cell markers by PAK1 also contributes to ...

    Authors: Nhi Huynh, Kai Wang, Mildred Yim, Chelsea J. Dumesny, Mauro S. Sandrin, Graham S. Baldwin, Mehrdad Nikfarjam and Hong He
    Citation: BMC Cancer 2017 17:431
    Content type: Research article Published on:

  28. In Italy women aged 50–69 are invited for a population-based breast cancer (BC) screening. Physicians, policy makers and patients associations agree on the need to inform women about the benefits and harms in ...

    Authors: Anna Roberto, Cinzia Colombo, Giulia Candiani, Livia Giordano, Paola Mantellini, Eugenio Paci, Roberto Satolli, Mario Valenza and Paola Mosconi
    Citation: BMC Cancer 2017 17:429
    Content type: Study protocol Published on:

  29. During posttreatment surveillance of head and neck cancer patients, imaging is insufficiently accurate for the early detection of relapsing disease. Free circulating tumor DNA (ctDNA) may serve as a novel biom...

    Authors: Joost H. van Ginkel, Manon M. H. Huibers, Robert J. J. van Es, Remco de Bree and Stefan M. Willems
    Citation: BMC Cancer 2017 17:428
    Content type: Research article Published on:

  30. To investigate the feasibility of strain elastography imaging in early detecting and predicting treatment response in patients receiving concurrent chemo-radiotherapy (CCRT) for locally advanced cervical cancer.

    Authors: Yan Xu, Lijing Zhu, Baorui Liu, Tong Ru, Huanhuan Wang, Jian He, Song Liu, Xiaofeng Yang, Zhengyang Zhou and Tian Liu
    Citation: BMC Cancer 2017 17:427
    Content type: Research article Published on:

  31. Esophageal carcinoma is the third most common gastrointestinal malignancy worldwide and is largely unresponsive to therapy. African-Americans have an increased risk for esophageal squamous cell carcinoma (ESCC...

    Authors: Hayriye Verda Erkizan, Kory Johnson, Svetlana Ghimbovschi, Deepa Karkera, Gregory Trachiotis, Houtan Adib, Eric P. Hoffman and Robert G. Wadleigh
    Citation: BMC Cancer 2017 17:426
    Content type: Research article Published on:

  32. The overexpression of human epidermal growth factor receptor-2 (HER2) in breast cancer is a poor prognosis. Trastuzumab improves overall survival but is associated with cardiotoxicity, especially a decline in ...

    Authors: Quentin Jacquinot, Nathalie Meneveau, Marion Chatot, Franck Bonnetain, Bruno Degano, Malika Bouhaddi, Gilles Dumoulin, Dewi Vernerey, Xavier Pivot and Fabienne Mougin
    Citation: BMC Cancer 2017 17:425
    Content type: Study protocol Published on:

  33. Co-occurrence of multiple sclerosis (MS) and glial tumours (GT) is uncommon although occasionally reported in medical literature. Interpreting the overlapping radiologic and clinical characteristics of glial t...

    Authors: Ema Kantorová, Michal Bittšanský, Štefan Sivák, Eva Baranovičová, Petra Hnilicová, Vladimír Nosáľ, Daniel Čierny, Kamil Zeleňák, Wolfgang Brück and Egon Kurča
    Citation: BMC Cancer 2017 17:424
    Content type: Case report Published on:

  34. Little information is available concerning how patient delay may be affected by mass disasters. The main objectives of the present study are to identify whether there was a post-disaster increase in the risk o...

    Authors: Akihiko Ozaki, Shuhei Nomura, Claire Leppold, Masaharu Tsubokura, Tetsuya Tanimoto, Takeru Yokota, Shigehira Saji, Toyoaki Sawano, Manabu Tsukada, Tomohiro Morita, Sae Ochi, Shigeaki Kato, Masahiro Kami, Tsuyoshi Nemoto, Yukio Kanazawa and Hiromichi Ohira
    Citation: BMC Cancer 2017 17:423
    Content type: Research article Published on:

  35. Ovarian cancer is the leading cause of death among gynecologic diseases in Western countries. We have previously identified a miR-200-E-cadherin axis that plays an important role in ovarian inclusion cyst form...

    Authors: Junzheng Yang, Yilan Zhou, Shu-Kay Ng, Kuan-Chun Huang, Xiaoyan Ni, Pui-Wah Choi, Kathleen Hasselblatt, Michael G. Muto, William R. Welch, Ross S. Berkowitz and Shu-Wing Ng
    Citation: BMC Cancer 2017 17:422
    Content type: Research article Published on:

  36. Previous studies have provided limited support to the association between tobacco smoking and lymphomas with weak evidence of a dose-response relationship.

    Authors: Martina Taborelli, Maurizio Montella, Massimo Libra, Rosamaria Tedeschi, Anna Crispo, Maria Grimaldi, Luigino Dal Maso, Diego Serraino and Jerry Polesel
    Citation: BMC Cancer 2017 17:421
    Content type: Research article Published on:

  37. Relapse in localized Ewing sarcoma patients has been a matter of concern regarding poor prognosis. Therefore, we investigated the impact of local control modality (surgery, surgery plus radiotherapy, and radio...

    Authors: Ricardo G. Becker, Lauro J. Gregianin, Carlos R. Galia, Reynaldo Jesus-Garcia Filho, Eduardo A. Toller, Gerardo Badell, Suely A. Nakagawa, Alexandre David, André M. Baptista, Eduardo S. Yonamime, Osvaldo A. Serafini, Valter Penna, Julie Francine C. Santos and Algemir L. Brunetto
    Citation: BMC Cancer 2017 17:420
    Content type: Research article Published on:

  38. Angiogenesis is essential for the progression and metastatic spread of solid tumours. Expression of vascular endothelial growth factor (VEGF) has been linked to poor survival among osteosarcoma patients but th...

    Authors: Marie-Dominique Tabone, Laurence Brugières, Sophie Piperno-Neumann, Marie-Ange Selva, Perrine Marec-Bérard, Hélène Pacquement, Cyril Lervat, Nadège Corradini, Jean-Claude Gentet, Rémy Couderc, Aurélie Chevance, Céline Mahier-Ait Oukhatar, Natacha Entz-Werle, Jean-Yves Blay and Marie-Cecile Le Deley
    Citation: BMC Cancer 2017 17:419
    Content type: Research article Published on:

  39. A high rate of glycolysis leading to elevated lactate content has been linked to poor clinical outcomes in patients with head and neck and cervical cancer treated with radiotherapy. Although the biological exp...

    Authors: Eric Leung, Rob A. Cairns, Naz Chaudary, Ravi N. Vellanki, Tuula Kalliomaki, Eduardo H. Moriyama, Hilda Mujcic, Brian C. Wilson, Bradly G. Wouters, Richard Hill and Michael Milosevic
    Citation: BMC Cancer 2017 17:418
    Content type: Research article Published on:

  40. CD40 signalling can synergise with chemotherapy in preclinical cancer models, and early clinical studies are promising. We set out to define the immunological changes associated with this therapeutic combinati...

    Authors: Alison M. McDonnell, Alistair Cook, Bruce W. S. Robinson, Richard A. Lake and Anna K. Nowak
    Citation: BMC Cancer 2017 17:417
    Content type: Research article Published on:

  41. Class III radical hysterectomy (RH III)_plus pelvic lymphadenectomy is the standard surgery for early stage cervical cancer (CC) patients, the 5 year survival rate is about 90%, but pelvic floor disorders espe...

    Authors: Xiu-Li Sun, Hai-Bo Wang, Zhi-Qi Wang, Ting-ting Cao, Xin Yang, Jing-Song Han, Yang-feng Wu, Kathleen H. Reilly and Jian-Liu Wang
    Citation: BMC Cancer 2017 17:416
    Content type: Study protocol Published on:

  42. Venous thromoboembolism (VTE) is a frequent and burdensome complication of metastatic colorectal cancer (CRC). However, the epidemiology of VTE in patients with localized CRC after surgery in curative intent i...

    Authors: Jakob Michael Riedl, Florian Posch, Angelika Bezan, Joanna Szkandera, Maria Anna Smolle, Thomas Winder, Christopher H. Rossmann, Renate Schaberl-Moser, Martin Pichler, Michael Stotz, Herbert Stöger and Armin Gerger
    Citation: BMC Cancer 2017 17:415
    Content type: Research article Published on:

  44. Patients undergoing surgery for esophageal cancer have a high risk for postoperative deterioration of lung function and pulmonary complications. This is partly due to one-lung ventilation during thoracotomy. T...

    Authors: Daniel Pfirrmann, Suzan Tug, Oana Brosteanu, Matthias Mehdorn, Martin Busse, Peter P. Grimminger, Florian Lordick, Torben Glatz, Jens Hoeppner, Hauke Lang, Perikles Simon and Ines Gockel
    Citation: BMC Cancer 2017 17:413
    Content type: Study protocol Published on:

  45. The anaplastic lymphoma kinase tyrosine kinase inhibitors (ALK-TKIs) have been administered to patients with ALK-positive non-small cell lung cancer for a long period of time and show a promising response. How...

    Authors: Qian Zhu, Hao Hu, De-Sheng Weng, Xiao-Fei Zhang, Chang-Long Chen, Zi-Qi Zhou, Yan Tang and Jian-Chuan Xia
    Citation: BMC Cancer 2017 17:412
    Content type: Research article Published on:

  46. Studies comparing the effect of antiangiogenic agents targeting different angiogenic pathways are sparse. The purpose of this study was to compare the effect of properdistatin and sunitinib treatment in a prec...

    Authors: Jon-Vidar Gaustad, Trude G. Simonsen, Lise Mari K. Andersen and Einar K. Rofstad
    Citation: BMC Cancer 2017 17:411
    Content type: Research article Published on:

  47. Soft tissue sarcomas are rare entities with over 50 histological subtypes. Liposarcoma (LS) is the most common neoplasm in this group; it is a complex neoplasm that is divided into different histological subty...

    Authors: Carolin Knebel, Ulrich Lenze, Florian Pohlig, Florian Lenze, Norbert Harrasser, Christian Suren, Jonathan Breitenbach, Hans Rechl, Rüdiger von Eisenhart-Rothe and Heinrich M. L. Mühlhofer
    Citation: BMC Cancer 2017 17:410
    Content type: Research article Published on:

  48. Granulin-epithelin precursor (GEP) is a secretory growth factor, which has been demonstrated to control cancer growth, invasion, drug resistance and immune escape. Our previous studies and others also demonstr...

    Authors: Chi Wai Yip, Ching Yan Lam, Terence C. W. Poon, Tan To Cheung, Phyllis F. Y. Cheung, Sze Wai Fung, Xiao Qi Wang, Idy C.Y. Leung, Linda W. C. Ng, Chung Mau Lo, George S. W. Tsao and Siu Tim Cheung
    Citation: BMC Cancer 2017 17:409
    Content type: Research article Published on:

  49. Chemotherapy plus bevacizumab is a standard first-line treatment for unresectable metastatic colorectal cancer patients. Different chemotherapy backbones may be chosen, including one to three drugs, based on p...

    Authors: Chiara Cremolini, Federica Marmorino, Fotios Loupakis, Gianluca Masi, Carlotta Antoniotti, Lisa Salvatore, Marta Schirripa, Luca Boni, Vittorina Zagonel, Sara Lonardi, Giuseppe Aprile, Emiliano Tamburini, Vincenzo Ricci, Monica Ronzoni, Filippo Pietrantonio, Chiara Valsuani…
    Citation: BMC Cancer 2017 17:408
    Content type: Study protocol Published on:

  50. Ridaforolimus is a mammalian target of rapamycin inhibitor that has activity in solid tumors. Paclitaxel and carboplatin have broad antineoplastic activity in many cancers. This phase I trial was conducted to ...

    Authors: Hye Sook Chon, Sokbom Kang, Jae K. Lee, Sachin M. Apte, Mian M. Shahzad, Irene Williams-Elson and Robert M. Wenham
    Citation: BMC Cancer 2017 17:407
    Content type: Research article Published on:

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