Fig. 3
Leave-one-out analysis of bidirectional mendelian randomization in cytokines and MPN.The left side of the forest plot represents the SNPs for which the leave-one-out analysis was performed, and the short line parallel to the x-axis represents the 95% confidence interval for the OR/beta value of the MR analysis after excluding the corresponding SNPs. As shown in the figure, the overall error line does not change much after excluding each SNP, and all OR/beta values are on the 0 side, indicating that the results are reliable (A):Forest plots for the exposure of IL-2ra. B Forest plots for the exposure of IP-10. C Forest plots for the outcome of IL-10. D Forest plots for the outcome of MIG. E Forest plots for the outcome of RANTES