Variable | DOK3 | P value | M2-TAMs | P value | ||
---|---|---|---|---|---|---|
Weak (%) | Strong (%) | Weak (%) | Strong (%) | |||
Sex | Â | Â | 0.406 | Â | Â | 0.085* |
 Male | 27 (57.4) | 46 (50.0) |  | 27 (44.3) | 46 (59.0) |  |
 Female | 20 (42.6) | 46 (50.0) |  | 34 (55.7) | 32 (41.0) |  |
Age (yr) | Â | Â | 0.042* | Â | Â | 0.372 |
 < 60 | 22 (46.8) | 27 (29.3) |  | 24 (39.3) | 25 (32.1) |  |
 ≥ 60 | 25 (53.2) | 65 (70.7) |  | 37 (60.7) | 53 (67.9) |  |
Survival status | Â | Â | 0.004** | Â | Â | 0.052 |
 Alive | 36 (76.6) | 47 (51.1) |  | 42 (68.9) | 41 (52.6) |  |
 Dead | 11 (23.4) | 45 (48.9) |  | 19 (31.1) | 37 (47.4) |  |
Tobacco smoking | Â | Â | 0.026* | Â | Â | 0.632 |
 No | 18 (38.3) | 19 (20.7) |  | 15 (24.6) | 22 (28.2) |  |
 Yes | 29 (61.7) | 73 (79.3) |  | 46 (75.4) | 56 (71.8) |  |
Alcohol consumption | Â | Â | 0.614 | Â | Â | 0.000*** |
 No | 21 (44.7) | 37 (40.2) |  | 35 (57.4) | 23 (29.5) |  |
 Yes | 26 (55.3) | 55 (59.8) |  | 26 (42.6) | 55 (70.5) |  |
Baseline severe dysphagia (Gr.3–6) |  |  | 0.000*** |  |  | 0.028* |
 No | 38 (80.9) | 41 (44.6) |  | 43 (70.5) | 36 (46.2) |  |
 Yes | 9 (19.1) | 51 (55.4) |  | 18 (29.5) | 42 (53.8) |  |
Diet | Â | Â | 0.138 | Â | Â | 0.097 |
 Vegetarian | 7 (14.9) | 0 |  | 5 (8.2) | 2 (2.6) |  |
 Non-vegetarian | 40 (85.1) | 92 (100) |  | 56 (91.8) | 76 (97.4) |  |
Milk & dairy products | Â | Â | 0.677 | Â | Â | 0.240 |
 Never | 1 (2.1) | 1 (1.1) |  | 0 | 2 (2.6) |  |
 Less than once a week | 10 (21.3) | 12 (13.0) |  | 10 (16.4) | 12 (15.4) |  |
 More than once a week | 36 (76.6) | 79 (85.9) |  | 51 (83.6) | 64 (82.0) |  |
T stage | Â | Â | 0.023* | Â | Â | 0.017* |
 T1 ~ T2 | 31 (66.0) | 42 (45.7) |  | 39 (63.9) | 34 (43.6) |  |
 T3 ~ T4 | 16 (34.0) | 50 (54.3) |  | 22 (36.1) | 44 (56.4) |  |
N stage | Â | Â | 0.088 | Â | Â | 0.319 |
 N0 | 34 (72.3) | 53 (57.6) |  | 41 (67.2) | 46 (59.0) |  |
 N ( +) | 13 (27.7) | 39 (42.4) |  | 20 (32.8) | 32 (41.0) |  |
Clinical stage | Â | Â | 0.697 | Â | Â | 0.025* |
 I ~ II | 20 (42.6) | 36 (39.1) |  | 31 (50.8) | 25 (32.1) |  |
 III ~ IV | 27 (57.4) | 56 (60.9) |  | 30 (49.2) | 53 (67.9) |  |
Recurrence | Â | Â | 0.675 | Â | Â | 0.114 |
 Yes | 9 (19.1) | 15 (16.3) |  | 7 (11.5) | 17 (21.8) |  |
 No | 38 (80.9) | 77 (83.7) |  | 54 (88.5) | 61 (78.2) |  |
Tumor size (cm) | Â | Â | 0.000*** | Â | Â | 0.619 |
 < 3 | 29 (61.7) | 27 (29.3) |  | 26 (42.6) | 30 (38.5) |  |
 ≥ 3 | 18 (38.3) | 65 (70.7) |  | 35 (57.4) | 48 (61.5) |  |
Differentiation | Â | Â | 0.256 | Â | Â | 0.083 |
 Well | 33 (70.2) | 47 (51.1) |  | 42 (68.85) | 38 (48.7) |  |
 Moderate | 10 (21.3) | 28 (30.4) |  | 14 (22.95) | 24 (30.8) |  |
 Poor | 4 (8.5) | 17 (18.5) |  | 5 (8.20) | 16 (20.5) |  |
Oral hygiene habits | Â | Â | 0.020* | Â | Â | 0.044* |
 Good | 5 (10.6) | 15 (16.3) |  | 8 (13.1) | 12 (15.4) |  |
 Average | 15 (31.9) | 36 (39.1) |  | 22 (36.1) | 29 (37.2) |  |
 Bad | 27 (57.5) | 41 (44.6) |  | 31 (50.8) | 37 (47.4) |  |
Periodontal condition | Â | Â | 0.013* | Â | Â | 0.248 |
 Well | 15 (31.9) | 13 (14.1) |  | 15 (24.6) | 13 (16.7) |  |
 Poor | 32 (68.1) | 79 (85.9) |  | 46 (75.4) | 65 (83.3) |  |
Treatment | Â | Â | 0.175 | Â | Â | 0.035* |
 Surgery | 11 (23.4) | 36 (39.1) |  | 19 (31.1) | 28 (35.9) |  |
 Radiotherapy | 14 (29.8) | 23 (25.0) |  | 11 (18.0) | 26 (33.3) |  |
 Chemoradiation/comprehensive | 22 (46.8) | 33 (35.9) |  | 31 (50.8) | 24 (30.8) |  |