Fig. 5
From: CHOP regulated by METTL14-m6A affects cell cycle arrest and regorafenib sensitivity in HCC cells
The Influence of the METTL14/CHOP axis on the sensitivity of HCC cells to Regorafenib. (A) Assessment of the activity of the cells using the CCK8 assay. (B) Evaluation of the proliferation rate of SK-Hep-1 and HCC-LM3 cells using EdU staining. (C) Colony formation assay to measure the proliferative activity of SK-Hep-1 and HCC-LM3 cells. (D) Detection of the apoptosis rate using FCM. * P < 0.05 vs. Regorafenib + sh-NC, # P < 0.05 vs. Regorafenib + oe-NC, & P < 0.05 vs. Regorafenib + oe-NC + oe-NC, $ P < 0.05 vs. Regorafenib + oe-METTL14 + oe-NC