Fig. 3
From: CHOP regulated by METTL14-m6A affects cell cycle arrest and regorafenib sensitivity in HCC cells
METTL14-mediated m6A methylation suppresses CHOP expression. (A) RIP assay for detecting the m6A methylation levels of CHOP. (B) WB analysis for the expression of METTL3, METTL14, FTO, and ALKBH5 in SK-Hep-1 and HCC-LM3 cells. (C-D) RT-qPCR and WB analysis for the expression of METTL14 and CHOP. (E) RIP assay for detecting the m6A levels of CHOP. * P < 0.05 vs. vehicle, #P < 0.05 vs. sh-NC, &P < 0.05 vs. oe-NC