Fig. 1
From: CHOP regulated by METTL14-m6A affects cell cycle arrest and regorafenib sensitivity in HCC cells
Inhibition of HCC proliferation by Regorafenib. (A) CCK8 Assay for the screening of Regorafenib-Sensitive HCC lines and determination of optimal intervention concentration of Regorafenib. (B) Determination of the activity of SK-Hep-1 and HCC-LM3 cells using the CCK8 assay. (C) Assessment of the proliferation rate of SK-Hep-1 and HCC-LM3 cells using EdU staining. (D) Evaluation of the proliferative activity of SK-Hep-1 and HCC-LM3 cells using the colony formation assay. (E) Detection of the apoptosis rate in SK-Hep-1 and HCC-LM3 cells using FCM. *P < 0.05 vs. Vehicle