Fig. 3

T cell exhaustion and B cell response in COVID-19 patients with defined phenotype. A-D: CD8 + T cell differentiation of Naïve T, TCM, TEM, and TEMRA in 5 groups with CD8^domB^dep, CD8^domB⁺, CD4^domB⁺, CD4/CD8^norB^dep, and CD4/CD8^norB⁺; E-H: CD4 + T cell differentiation of Naïve T, TCM, TEM, and TEMRA in 5 groups; I-L: B cell response of Naïve B, memory B, transitional B and plasmablast in 5 phenotypic groups. *P < 0.05, * *P < 0.01, ***P < 0.001 (Kruskal-Wallis test or Brown-Forsythe ANOVA test)