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Fig. 4 | BMC Cancer

Fig. 4

From: 25-hydroxycholesterol promotes proliferation and metastasis of lung adenocarcinoma cells by regulating ERβ/TNFRSF17 axis

Fig. 4

ERβ positively regulated the expression of TNFRSF17. A. Differential genes were identified between ERβ-high and ERβ-low groups which were stratified based on the median ERβ expression. Cluster analysis of the top 10 upregulated and downregulated genes. B. Volcanic map of differential genes between ERβ-high and ERβ-low groups. C. The correlation between the expression of ERβ and TNFRSF17. D. The effect of ERβ knockdown on the mRNA expression of TNFRSF17in the presence of 0.085 µM25-HC. E. The effect of ERβ knockdown on the protein expression of TNFRSF17 in the presence of 0.085 µM 25-HC.Data were shown as mean ± SD of at least three independent experiments.*, p < 0.05; **, p < 0.01;*** p < 0.0001

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BMC Cancer

ISSN: 1471-2407

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