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Table 2 Univariate and multivariate Cox models evaluated the effect of the depth of PNI on OS and DFS in Stage II CRC patients

From: The depth of perineural invasion is an independent prognostic factor for stage II colorectal cancer

 

Univariate Cox model

Multivariate Cox model

Hazard Ratio (95% CI)

P-value

Hazard Ratio (95% CI)

P-value

OS: the depth of PNIa

 Non-PNI

    

 sup-PNI

1.154(0.755–1.764)

0.509

1.017(0.654–1.583)

0.939

 deep-PNI

5.505(3.685–8.224)

< 0.001

3.546(2.307–5.449)

< 0.001

DFS: the depth of PNIb

 Non-PNI

    

 sup-PNI

1.366(1.019–1.831)

0.037

1.258(0.928–1.706)

0.140

 deep-PNI

4.360(3.095–6.142)

< 0.001

2.921(2.032–4.198)

< 0.001

  1. Parameters with P values < 0.05 in the univariate Cox model were then entered into a final multivariable Cox regression model. Detailed data are shown in Supplementary Table 1 and Table 2
  2. aAdjusted for the depth of PNI, Gender, Age, BMI, CEA, T4, Differentiation, dMMR, Vascular Invasion, Harvested Lymph Nodes
  3. bAdjusted for the depth of PNI, Gender, Age, CEA, Tumor Location, T4, Differentiation, dMMR, Vascular Invasion, Harvested Lymph Nodes
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BMC Cancer

ISSN: 1471-2407

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