Fig. 1
From: CircPHGDH downregulation decreases papillary thyroid cancer progression through miR-122-5p/PKM2 axis
Relative expression of circPHGDH in PTC tissues and cell lines. (A) High-throughput sequencing detected show the abnormal expression of circRNA between PTC tissue and paired non-cancerous tissue. (B) RT-qPCR detection show the expression of circPHGDH (hsa_circ_0013768) in ten pair of PTC tissue and paired non-cancerous tissue. Data are presented as means ± SD. ***P < 0.001 vs. Normal. (C) FISH detection show the expression and subcellular distribution of circPHGDH in PTC tissue and paired non-cancerous tissue. Scale bar, 50 μm. (D) RT-qPCR detection show the expression of circPHGDH in PTC cell line FTC-133, SW579, K1, TPC-1 and a human thyroid epithelial cell line Nthy-ori 3 − 1. Data are presented as means ± SD. ***P < 0.001 vs. Nthy-ori 3 − 1. (E) The genomic loci of the PHGDH gene and circPHGDH.