From: Impact of age on central lymph nodes involvement in papillary thyroid cancer
Variable | Group I (≤ 20y) 27 ptn | Group II (> 20-40y) 146 ptn | Group III (> 40y) 142 ptn | Significance |
---|---|---|---|---|
Sex Male Female | 8 19 | 31 115 | 42 100 | 0.24 |
BMI median (range) | 25.1 (17.5–37.5) | 31 (19.5–46.7) | 34 (20.5–56.9) | < 0.001 |
MNG association No Yes | 18 8 | 85 56 | 55 84 | < 0.001 |
FNAC (Besthesda) I II III IV V VI | 0 0 0 5 10 7 | 7 3 5 25 65 15 | 0 9 9 12 64 28 | 0.003 |
Operative time median (range) | 180 (90–540) | 180 (60–600) | 180 (60–510) | 0.3 |
Surgery Ipsilateral central Bilateral central Ipsilateral central & lateral Bilateral central & ipsilateral lateral Bilateral central & lateral Ipsilateral central & bilateral lateral | 6 5 6 4 5 1 | 50 22 41 19 11 3 | 46 20 44 11 14 7 | 0.54 |
Tumour size median (range) | 2 (0.5-8) | 2 (0.4-6) | 2.5 (0.2-7) | 0.19 |
Pathologic focality Unifocal Multifocal | 17 10 | 76 65 | 64 70 | 0.29 |
Pathologic laterality Unilateral Bilateral | 20 7 | 94 47 | 92 44 | 0.75 |
Extrathyroid extension No Yes | 16 9 | 81 27 | 75 47 | 0.08 |
Central node harvest median (range) | 6 (1–31) | 6 (1–23) | 5 (1–35) | 0.12 |
Central node status Negative Positive | 3 24 | 47 96 | 58 83 | 0.009 |
No of + ve central nodes median (range) | 4 (1–17) | 3 (1–20) | 3 (1–15) | 0.27 |
Lateral node harvest median (range) | 24 (3–98) | 16 (1–64) | 21 (2–73) | 0.004 |
Lateral node status Negative Positive | 2 15 | 9 63 | 9 67 | 0.99 |
No of lateral + ve nodes median (range) | 8 (2–43) | 5 (1–16) | 4 (1–24) | 0.22 |
T stage 1 2 3 4 | 10 10 6 1 | 59 50 22 5 | 47 40 41 9 | 0.14 |
N stage 0 1 | 3 24 | 44 99 | 47 95 | 0.07 |
Postop hypocalcaemia No Yes | 22 5 | 117 29 | 116 26 | 0.94 |
Postop nerve affection No Yes | 25 2 | 138 8 | 122 19 | 0.061 |
Length of hospital stay median (range) | 3 (1–10) | 2 (1–20) | 2 (1–25) | 0.013 |
Recurrence No Yes | 25 1 | 135 8 | 120 20 | 0.026 |
Estimated mean disease-free survival (95%CI) | 108.6 (100-117.1) | 106.4 (99.9-112.9) | 101.8 (89.8-113.8) | 0.043 |