Fig. 1From: Eukaryotic initiation factor 3a promotes the development of diffuse large B-cell lymphoma through regulating cell proliferationThe expression of eIF3a was upregulated in DLBCL and correlated with worse prognosis. (A) The expression levels of eIF3a in DLBCL and healthy control groups from GSE25638. (B) Kaplan-Meier curves for OS of DLBCL patients with high- or low- expressed eIF3a levels in GSE31312 (P = 0.0063). (C, D) The expression levels of eIF3a protein in DLBCL cell lines (LY1, LY3, LY8 and U2932) and PBMCs from healthy donors. The results of triplicate experiments were shown as the mean ± SD. (E, F) Compared with RHL, the expression level of eIF3a was significantly increased in DLBCL tissues. Original magnification, ×100 and ×400. (G) Kaplan-Meier survival analysis showed shorter OS in patients with positive expression of eIF3a. **P < 0.01, *** P < 0.001, **** P < 0.0001Back to article page