Evaluation of the diagnostic performance of colposcopy in the detection of cervical high-grade squamous intraepithelial lesions among women with transformation zone type 3

Table 1 Description of the study population

Characteristics	All (n = 764)
Age (years)
Mean ± SD	52.9 ± 11.8
< 45	176 (23.0%)
45–59	321 (42.0%)
≥ 60	267 (35.0%)
HPV status
Unknown or not performed	40 (5.2%)
Negative	109 (14.3%)
HPV16/18	162 (21.2%)
Non-16/18 HR-HPV	453 (59.3%)
Cytology results
Unknown or not performed	26 (3.4%)
NILM	535 (70.0%)
LSIL/ASCUS/AGUS	176 (23.0%)
HSIL+/ASC-H	27 (3.6%)
Colposcopic findings
Normal	558 (73.0%)
Low-grade lesion	139 (18.2%)
High-grade lesion	43 (5.6%)
Suspicious of cancer	24 (3.2%)
Histology results
<CIN2	680 (89.0%)
Normal/ cervicitis	527 (69.0%)
CIN1	153 (20.0%)
CIN2+	84 (11.0%)
CIN2/CIN3	62 (8.1%)
SqCC	18 (2.4%)
AC	4 (0.5%)
Colposcopist
Junior Senior Indication for colposcopy	525 (68.7%) 239 (31.3%)
Abnormal clinical symptoms Abnormal vaginal bleeding Abnormal vaginal discharge Post-coital bleeding Unusual appearance of the cervix Abnormal screening results	91 (11.9%) 31 (4.1%) 19 (2.5%) 25 (3.3%) 16 (2.1%) 673 (88.1%)

NILM, negative for intraepithelial lesion or malignancy; LSIL, low-grade squamous intraepithelial lesion; ASCUS, atypical squamous cells of undetermined significance; AGUS, atypical glandular cells of undetermined significance; ASC-H, atypical squamous cells-cannot exclude HSIL; HSIL, high-grade squamous intraepithelial lesion; CIN, cervical intraepithelial neoplasia; CIN2+, cervical intraepithelial neoplasia grade 2 or worse; CIN2, cervical intraepithelial neoplasia grade 2; CIN3, cervical intraepithelial neoplasia grade 3; SD, standard deviation; SqCC, squamous cell carcinoma; AC, adenocarcinoma

ISSN: 1471-2407