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Table 1 VTX-1-AdnaDetect test results of CTC and exosomal cfRNA analysis in 19 blood samples from 16 patients with mCRPC and resistance to ARI therapy. mCRPC: metastatic castration-resistant prostate cancer; AR: androgen receptor; AR-V7: AR splice variant 7; PSMA: prostate-specific membrane antigen; PSA: prostate-specific antigen; CTCs: circulating tumor cells; cfRNA: cell-free RNA.

From: Detecting androgen receptor (AR), AR variant 7 (AR-V7), prostate-specific membrane antigen (PSMA), and prostate-specific antigen (PSA) gene expression in CTCs and plasma exosome-derived cfRNA in patients with metastatic castration-resistant prostate cancer (mCRPC) by integrating the VTX-1 CTC isolation system with the QIAGEN AdnaTest

Patient ID

Sample #

AR

AR-V7

PSMA

PSA

CTC

cfRNA

CTC

cfRNA

CTC

cfRNA

CTC

cfRNA

1

1

+

+

+

-

+

+

+

+

2

+

+

+

+

+

+

+

+

2

1

+

+

-

-

+

-

-

-

2

+

-

-

-

-

-

-

-

3

1

+

+

-

-

-

-

-

+

4

1

+

+

-

-

+

+

+

+

5

1

+

-

-

-

-

-

-

-

6

1

+

-

+

-

-

+

-

-

7

1

+

-

-

-

-

+

-

-

8

1

-

+

-

-

-

-

-

-

9

1

+

+

-

-

+

-

-

-

2

+

+

-

-

-

+

-

-

10

1

+

+

-

-

-

-

-

-

11

1

+

+

-

-

-

-

-

+

12

1

+

+

-

-

-

-

-

-

13

1

-

-

-

-

-

-

-

-

14

1

-

+

-

-

-

-

-

-

15

1

+

-

-

-

-

-

-

-

16

1

+

-

-

-

-

-

-

+

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BMC Cancer

ISSN: 1471-2407

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