Table 3 Hierarchical multiple linear regression analysis of cancer-related fatigue among EC patients without esophagectomy

Demographic and clinical characteristics

0.068

0.107

Age

0.002

-0.034 to 0.038

0.094

0.925

0.005

Physical exercise (week)

-0.428

-0.854 to -0.002

2.010

0.045

-0.108

Time since diagnosis (year)

0.055

-0.642 to 0.752

0.157

0.875

0.029

Physical symptoms

0.644

0.571

Constipation

0.176

0.029 to 0.324

2.372

0.020

0.192

Diarrhea

0.209

0.035 to 0.383

2.391

0.019

0.181

Difficulty swallowing

0.210

0.101 to 0.320

3.818

< 0.001

0.273

Change in taste

0.034

-0.124 to 0.193

0.430

0.668

0.038

Abdominal distention

0.044

-0.104 to 0.193

0.593

0.555

0.048

Psychological symptoms

0.742

0.094

Depression

0.114

0.025 to 0.203

2.539

0.013

0.233

Anxiety

0.096

-0.008 to 0.201

1.832

0.070

0.170