Table 4 Cox proportional hazards model analysis of RFS in 320 patients with follow-up
Features | Status | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|
Hazard ratio | 95%CI | P value | Hazard ratio | 95%CI | P value | ||
Gender | Male | 1.534 | 0.671 ∼ 3.506 | 0.310 | NA | ||
Age | ≥ 70 | 2.235 | 0.756 ∼ 6.603 | 0.146 | NA | ||
Tumor size | 1−2 cm | 2.209 | 0.507–9.630 | 0.291 | NA | ||
2−3 cm | 0.200 | 0.555–16.665 | 0.200 | NA | |||
Smoking history | positive | 2.367 | 0.944 ∼ 5.937 | 0.066 | NA | ||
Gene mutation | positive | 3.674 | 1.240 ∼ 10.883 | 0.019 | 3.205 | 1.072 ∼ 9.581 | 0.037 |
Category of nodule | mGGN | 2.500 | 0.973 ∼ 6.426 | 0.057 | NA | ||
Lobulation | positive | 1.859 | 0.804 ∼ 4.300 | 0.147 | NA | ||
Spiculation | positive | 0.716 | 0.266 ∼ 1.929 | 0.508 | NA | ||
Vascular changes | positive | 1.006 | 0.442 ∼ 2.294 | 0.988 | NA | ||
Air-bronchogram | positive | 0.686 | 0.289 ∼ 1.629 | 0.393 | NA | ||
Bubble-like lucency | positive | 0.885 | 0.387 ∼ 2.019 | 0.771 | NA | ||
Pleural retraction | positive | 2.154 | 0.927 ∼ 5.006 | 0.074 | NA | ||
TLS | positive | 0.380 | 0.149 ∼ 0.965 | 0.042 | 0.451 | 0.176 ∼ 1.154 | 0.097 |