Table 2 Association of ER, PR and Her2/neu receptor expression with different clinicopathological factors

Marital status

 Married

54 (50)

54 (50)

0.584

49 (45.3)

59 (54.6)

0.807

47 (43.5)

56 (51.8)

5 (4.6)

0.458

 Unmarried

5 (41.6)

7 (58.3)

5 (41.6)

7 (58.3)

7 (58.3)

4 (3.7)

1 (0.9)

Age category

 ≤ 39

26 (50)

26 (50)

0.873

24 (44.4)

28 (55.5)

0.824

20 (37.0)

28 (46.6)

4 (66.6)

0.29

 ≥ 40

33 (50.7)

35 (49.2)

30 (44.1)

38 (55.8)

34 (62.9)

32 (53.3)

2 (33.3)

Parity

 Multiparous

50 (53.1)

44 (46.8)

0.219

46 (48.9)

48 (51.0)

0.183

41 (43.6)

49 (52.1)

4 (4.2)

0.755

 Nulliparous

2 (33.3)

4 (66.6)

1 (16.6)

5 (83.3)

3 (50)

2 (33.3)

1 (16.6)

 Infertile

1 (14.3)

6 (85.7)

1 (14.3)

6 (85.7)

3 (42.8)

4 (51.1)

0

 Not applicable

6 (46.1)

7 (53.8)

6 (46.1)

7 (53.8)

7 (53.8)

5 (38.4)

1 (7.6)

History breast feeding

 Yes

46 (52.2)

42 (47.7)

0.598

42 (47.7)

46 (52.2)

0.304

41 (46.5)

43 (48.8)

4 (4.5)

0.838

 No

5 (50)

5 (50)

4 (40)

6 (60)

3 (30)

6 (60)

1 (10)

 Not Applicable

8 (36.3)

14 (63.6)

8 (36.3)

14 (63.6)

10 (45.4)

11 (50)

1 (4.5)

Age in menopause

 < 40 years

2 (50)

2 (50)

0.269

2 (50)

2 (50)

0.148

0

4 (100)

0

0.428

 40–50 years

17 (42.5)

23 (57.5)

15 (37.5)

25 (62.5)

17 (42.5)

21 (52.5)

2 (5.0)

 > 50 years

9 (75)

3 (25)

9 (75)

3 (25)

5 (41.6)

7 (58.3)

0

 Not in menopause

31 (48.4)

33 (51.5)

28 (43.7)

36 (56.2)

32 (50)

28 (43.7)

4 (6.2)

 Postmenopausal

28 (49.1)

29 (50.8)

26 (45.6)

31 (54.3)

23 (40.3)

32 (56.1)

2 (3.5)

Ethnicity

 Pashtun

24 (44.4)

30 (55.6)

0.494

26 (48.1)

28 (51.8)

0.962

25 (56.8)

18 (40.9)

1 (2.2)

0.028

 Tajik

28 (58.3)

20 (41.6)

21 (43.5)

27 (56.5)

17 (38.6)

26 (59)

5 (11.3)

 Hazara

2 (28.5)

5 (71.4)

2 (28.5)

5 (71.4)

1 (14.2)

6 (85.7)

0

 Uzbek/ Turkmen

3 (42.8)

4 (57.1)

3 (42.8)

4 (57.1)

5 (71.4)

2 (28.6)

0

 Others

2 (50)

2 (50)

2 (50)

2 (50)

2 (50)

2 (50)

0

Residential area

 Urban

45 (76.2)

14 (23.8)

0.06

39 (47.5)

43 (52.4)

0.407

37 (45.1)

39 (47.5)

6 (7.3)

0.559

 Rural

37 (60.6)

24 (39.3)

15 (39.4)

23 (60.5)

23 (60.5)

15 (39.5)

0

Family history breast cancer

 Yes

16(55.1)

13 (44.8)

0.459

15 (51.7)

14 (48.2)

0.403

17 (58.6)

11 (37.9)

1 (3.4)

0.555

 No

43 (53.0)

38 (46.9)

29 (56.8)

52 (43.1)

43 (47.2)

43 (47.2)

5 (5.4)

Tumor size category

 < 2 cm

2 (33.3)

4 (66.6)

0.047

1 (16.6)

5 (83.3)

0.021

2 (30)

4 (60)

0

0.883

 2-5 cm

29 (65.9)

15 (34.0)

27 (69.2)

12 (30.7)

12 (33.3)

23 (63.8)

1 (2.7)

 > 5 cm

6 (37.5)

10 (62.5)

4 (19.0)

17 (80.9)

7 (43.7)

8 (50)

1 (6.2)

 NA^a

22 (40.7)

32 (59.2)

22 (40.7)

32 (59.2)

25 (46.2)

25 (46.2)

4 (7.4)

Histological grade

 Grade I

3 (100)

0

0.014

3 (100)

0

0.105

0

3 (100)

0

0.021

 Grade II

38 (58.4)

27 (41.5)

32 (49.2)

33 (50.7)

22 (33.8)

40 (61.5)

3 (4.6)

 Grade III

14 (31.8)

30 (68.1)

17 (38.6)

27 (61.3)

28 (63.6)

14 (31.8)

2 (4.5)

 Not graded

4 (50)

4 (50)

2 (25)

6 (75)

4 (50)

3 (37.5)

1 (12.5)

Histological type

 IDC-NOS

53 (48.1)

57 (51.8)

0.059

49 (44.5)

61 (55.4)

0.232

48 (43.6)

57 (51.8)

5 (4.5)

0.388

 Lobular carcinoma

5 (100)

0

4 (80)

1 (20)

2 (40)

2 (40)

1 (20)

 Apocrine carcinoma

1 (100)

0

1 (33.3)

2 (66.6)

3 (100)

0

0

 Others

0

2 (100)

0

2 (100)

1 (50)

1 (50)

0

Age at menarche

 < 12 Year

23 (46.5)

26 (53.4)

0.095

20 (40.8)

29 (59.1)

0.5

27 (55.1)

21 (42.8)

1 (2.0)

0.14

 12–13 year

20 (40)

29 (60)

21 (42.8)

28 (57.1)

20 (40.8)

25 (51.0)

4 (8.1)

 > 13 year

13 (69.2)

5 (30.7)

11 (61.1)

7 (38.8)

6 (33.3)

12 (66.6)

0

 Unknown

3 (75)

1 (25)

2 (50)

2 (50)

2 (40)

2 (40)

1 (20)

Tumor side

 Right

30 (50)

30 (50)

0.982

29 (48.3)

31 (51.6)

0.742

22 (36.6)

36 (60)

2 (3.3)

0.149

 Left

28 (48.2)

30 (51.7)

24 (41.3)

34 (58.6)

30 (51.7)

24 (41.3)

4 (6.8)

 Bilateral

1 (50)

1 (50)

1 (50)

1 (50)

2 (100)

0

0