Table 1 Univariable analyses of risk factors for oral cancer recurrence. (N = 173)
From: Factors associated with recurrence in patients with oral cancer in Mongolia
Cancer recurrence | P value* | cOR& | 95% CI | |||||
|---|---|---|---|---|---|---|---|---|
No | Yes | |||||||
Count | Percent | Count | Percent | |||||
Age | ||||||||
≤ 60 years | 73 | 86.9% | 11 | 13.1% | 0.489 | 1 | ||
> 60 years | 74 | 83.1% | 15 | 16.9% | 1.34 | (0.58–3.12) | ||
Gender | ||||||||
Female | 60 | 93.8% | 4 | 6.3% | 0.013 | 1 | ||
Male | 87 | 79.8% | 22 | 20.2% | 3.79 | (1.24–11.57) | ||
Residence | ||||||||
Urban | 65 | 85.5% | 11 | 14.5% | 0.856 | 1 | ||
Rural | 82 | 84.5% | 15 | 15.5% | 1.08 | (0.46–2.51) | ||
Education | ||||||||
Advanced | 35 | 79.5% | 9 | 20.5% | 0.149 | 1 | ||
None | 5 | 100.0% | 0 | 0.0% | * | * | ||
Basic | 20 | 76.9% | 6 | 23.1% | 1.17 | (0.36–3.76) | ||
Intermediate | 74 | 91.4% | 7 | 8.6% | 0.38 | (0.13–1.07) | ||
Short-cycle tertiary | 13 | 76.5% | 4 | 23.5% | 1.19 | (0.31–4.56) | ||
Tobacco consumption | ||||||||
No | 82 | 84.5% | 15 | 15.5% | 0.856 | 1 | ||
Yes | 65 | 85.5% | 11 | 14.5% | 0.92 | (0.39–2.15) | ||
Alcohol consumption | ||||||||
No | 113 | 86.3% | 18 | 13.7% | 0.402 | 1 | ||
Yes | 34 | 81.0% | 8 | 19.0% | 1.48 | (0.59–3.69) | ||
Tobacco and alcohol use | ||||||||
No | 115 | 85.2% | 20 | 14.8% | 0.882 | 1 | ||
Yes | 32 | 84.2% | 6 | 15.8% | 1.08 | (0.39–2.91) | ||
Chipped tooth | ||||||||
No | 134 | 84.8% | 24 | 15.2% | 0.848 | 1 | ||
Yes | 13 | 86.7% | 2 | 13.3% | 0.86 | (0.18–4.05) | ||
Denture sores | ||||||||
No | 128 | 85.3% | 22 | 14.7% | 0.733 | 1 | ||
Yes | 19 | 82.6% | 4 | 17.4% | 1.22 | (0.38–3.94) | ||
Family history | ||||||||
No | 135 | 86.5% | 21 | 13.5% | 0.081 | 1 | ||
Yes | 12 | 70.6% | 5 | 29.4% | 2.68 | (0.85–8.37) | ||
Precancerous conditions | ||||||||
No | 129 | 84.9% | 23 | 15.1% | 0.779 | 1 | ||
Leukoplakia | 8 | 80.0% | 2 | 20.0% | 1.4 | (0.28–7.03) | ||
Others | 10 | 90.9% | 1 | 9.1% | 0.56 | (0.07–4.59) | ||
Cancer location | ||||||||
Lip | 22 | 95.7% | 1 | 4.3% | 0.056 | 1 | ||
Hard palate | 9 | 100.0% | 0 | 0.0% | * | * | ||
Tongue | 62 | 78.5% | 17 | 21.5% | 6.03 | (0.75–48.02) | ||
Cheek lining | 9 | 90.0% | 1 | 10.0% | 2.44 | (0.14–43.47) | ||
Gums | 15 | 100.0% | 0 | 0.0% | * | * | ||
Floor of the mouth | 12 | 75.0% | 4 | 25.0% | 7.33 | (0.73–73.24) | ||
Soft palate | 15 | 93.8% | 1 | 6.3% | 1.46 | (0.08–25.31) | ||
Retromolar space | 3 | 60.0% | 2 | 40.0% | 14.66 | (0.99-215.31) | ||
Tumor size | ||||||||
T1 | 19 | 90.5% | 2 | 9.5% | 0.309 | 1 | ||
T2 | 50 | 90.9% | 5 | 9.1% | 0.95 | (0.17–5.32) | ||
T3 | 45 | 80.4% | 11 | 19.6% | 2.32 | (0.47–11.49) | ||
T4 | 33 | 80.5% | 8 | 19.5% | 2.31 | (0.44–11.98) | ||
Lymph node | ||||||||
N0 | 34 | 94.4% | 2 | 5.6% | 0.009 | 1 | ||
N > 1 | 91 | 79.1% | 24 | 20.9% | 4.48 | (1.01–19.99) | ||
NX | 22 | 100.0% | 0 | 0.0% | * | * | ||
Metastasis | ||||||||
M0 | 121 | 88.3% | 16 | 11.7% | 0.023 | 1 | ||
M1 | 2 | 50.0% | 2 | 50.0% | 7.56 | (0.99–57.47) | ||
MX | 24 | 75.0% | 8 | 25.0% | 2.52 | (0.97–6.55) | ||
Stage | ||||||||
2 | 24 | 96.0% | 1 | 4.0% | 0.047 | 1 | ||
1 | 11 | 100.0% | 0 | 0.0% | * | * | ||
3 | 63 | 86.3% | 10 | 13.7% | 3.81 | (0.46–31.38) | ||
4 | 49 | 76.6% | 15 | 23.4% | 7.34 | (0.92–58.94) | ||
Pathological grading | ||||||||
Well | 111 | 84.1% | 21 | 15.9% | 0.251 | 1 | ||
Moderate | 5 | 100.0% | 0 | 0.0% | * | * | ||
Poor | 28 | 90.3% | 3 | 9.7% | 0.57 | (0.16–2.03) | ||
Undifferentiated | 3 | 60.0% | 2 | 40.0% | 3.52 | (0.55–22.39) | ||
Treatment | ||||||||
Surgery | 103 | 93.6% | 7 | 6.4% | < 0.001 | 1 | ||
CT | 4 | 80.0% | 1 | 20.0% | 3.68 | (0.36–37.48) | ||
RT | 2 | 100.0% | 0 | 0.0% | * | * | ||
Surgery + CT | 12 | 80.0% | 3 | 20.0% | 3.68 | (0.84–16.14) | ||
Surgery + RT | 9 | 64.3% | 5 | 35.7% | 8.17 | (2.15–31.05) | ||
CT + RT | 7 | 87.5% | 1 | 12.5% | 2.1 | (0.22–19.56) | ||
Surgery + CT + RT | 9 | 50.0% | 9 | 50.0% | 14.71 | (4.43–48.85) | ||
Rehabilitation | ||||||||
Yes | 67 | 89.3% | 8 | 10.7% | 0.160 | 1 | ||
No | 80 | 81.6% | 18 | 18.4% | 1.88 | (0.77–4.61) | ||