Variable | n/N (%) | |
---|---|---|
Age, years | < 65 | 231/548 (42.2) |
65–75 | 211/548 (38.5) | |
> 75 | 106/548 (19.3) | |
Eastern Cooperative Oncology Group (ECOG) performance status | 0 | 103/546 (18.9) |
1 | 280/546 (51.3) | |
2 | 112/546 (20.5) | |
> 2 | 51/546 (9.3) | |
Presence of paraneoplastic syndromes | 51/545 (9.4) | |
Presence of at least one severe comorbidity† | 149/545 (27.3) | |
Presence of metastasis | None | 28/537 (5.2) |
Symptomatic brain metastasis only | 20/537 (3.7) | |
Asymptomatic brain metastasis only | 13/537 (2.4) | |
Multi-organ metastases including symptomatic brain metastasis | 252/537 (46.9) | |
Multi-organ metastases including asymptomatic brain metastasis | 224/537 (41.7) | |
Corticosteroid use before initiation of first-line therapy | 117/524 (22.3) |