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Fig. 1 | BMC Cancer

Fig. 1

From: NanoLuc Binary Technology as a methodological approach: an important new tool for studying the localization of androgen receptor and androgen receptor splice variant V7 homo and heterodimers

Fig. 1

Nano-Glo® Live Cell assay. A HEK-293 cells were transfected with all possible combinations of homo- and heterodimers (Ho and He) encoding the LargeBiT (LgBiT) and SmallBiT (SmBiT) subunits in the N- and C- terminal regions of the androgen receptor full length (AR) and androgen receptor splice variant 7 (AR-V7) proteins. B-C Luminescence measurements in HEK-293 cells transfected with AR-FL and AR-V7 homo and-heterodimers after treatment with 1 nM DHT or 10 µM enzalutamide. Luminescence in nonstimulated HEK-293 cells was set as base line. The data represent the mean ± SEM (n = 3)

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BMC Cancer

ISSN: 1471-2407

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