Fig. 7

Cachexia in KPCML1 mice occurs independently from metastasis. Adult mice were transplanted with Matrigel control or KPCML1 cells and standard endpoint measurements were obtained from mice presenting with or without liver metastasis, including body weight, spleen weight, heart weight, adipose weight, and weights from hindlimb muscles, tibialis anterior (TA), quadriceps (QUAD), and gastrocnemius (GAST). Met, metastatic; Non Met, non metastatic, Statistical analysis was performed using 1-way ANOVA (P < 0.05) with Dunnett’s multiple comparisons test in Graph Pad Prism. Data are shown as mean ± SEM. * represents p < 0.05