Fig. 5

The ceramide C18:C24 ratio is elevated in the serum of the KPCML1 orthotopic model and other mouse models of cancer cachexia. The ceramide ratios of C18:C24 are shown from sphingolipid analyses performed with serum from KPCML1 mice, compared to the KPC orthotopic model and KPP, C-26, and LLC mouse models of cancer cachexia. Statistical analysis was performed using unpaired two-tailed t test. Data are shown as mean ± SEM. * represents p < 0.05