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Fig. 4 | BMC Cancer

Fig. 4

From: Optimization of a mouse model of pancreatic cancer to simulate the human phenotypes of metastasis and cachexia

Fig. 4

KPCML1 mice recapitulate a cachexia phenotype. Mice were transplanted with Matrigel as control or KPCML1 cells and standard endpoint measurements were obtained including body weight (A), spleen weight (B), heart weight (C), adipose weight (D), and weights from hindlimb muscles, tibialis anterior (TA) (E), quadriceps (QUAD) (F), and gastrocnemius (GAST) (G). Statistical analysis was performed using unpaired two-tailed t test with unequal variance. Data are shown as mean ± SEM. * represents p < 0.05

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