Fig. 3
From: Regulation of cancer stem cells by CXCL1, a chemokine whose secretion is controlled by MCM2
Influence of MCM2 Expression on EMT Marker Proteins and Cell Migration in LCSCs. (A) Confirmation of the expression levels of EMT marker proteins E-cadherin, N-cadherin, and vimentin according to the expression levels of MCM2. Full-length blots are presented in Supplementary Fig. 1D. (B) Expression levels of Snail, Slug, Twist, and Zeb1, which are EMT regulators. Full-length blots are presented in Supplementary Fig. 1E. (C) Confirmation of cell migration and invasion ability regulated by MCM2. (D) Measurement of cell migration ability according to the expression level of MCM2. Sample derive from the same experiment and that blots were processed in parallel. Data are presented as the mean ± standard deviation of three replicates. Scale bar, 50 μm. *p˂0.001, **p˂0.0005