Fig. 6
From: Hsa_circ_0004872 alleviates meningioma progression by sponging miR-190a-3p/PTEN signaling
miR-190a-3p overexpression partially eliminated the antitumor effect mediated by hsa_circ_0004872 overexpression. IOMM-Lee and CH157-MN cells were transfected with pcDNA3.1, pcDNA3.1-circ_0004872 or co-transfected with pcDNA3.1-circ_0004872 plus miR-190a-3p mimics. (A) Cell viability was assessed using CCK8 assay. (B) Cell apoptosis was detected by flow cytometry. (C) Bax, Bcl-2, Cleaved-caspase3 and Caspase3 protein levels in cells were examined by Western blot. Data are presented as mean ± SD from at least three replicate experiments. *p < 0.05, **p < 0.01, ***p < 0.001