Fig. 4
From: Hsa_circ_0004872 alleviates meningioma progression by sponging miR-190a-3p/PTEN signaling
miR-190a-3p negatively regulated the PTEN/PI3K/AKT signaling pathway. (A) The potential binding site between PTEN and miR-190a-3p. (B) Dual-luciferase reporter gene assay showing the interaction between PTEN and miR-190a-3p. (C) MiR-190a-3p and PTEN expressions in IOMM-Lee and CH157-MN cells after mimics NC or miR-190a-3p mimics transfection were detected using qRT-PCR. (D) Western blot was employed to detect PTEN, PI3K, p-PI3K, AKT and p-AKT protein level in cells after mimics NC or miR-190a-3p mimics transfection. Data are presented as mean ± SD from at least three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001