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Fig. 2 | BMC Cancer

Fig. 2

From: Hsa_circ_0004872 alleviates meningioma progression by sponging miR-190a-3p/PTEN signaling

Fig. 2

Hsa_circ_0004872 overexpression inhibited proliferation and promoted the apoptosis in vitro. IOMM-Lee and CH157-MN cells were transfected with either pcDNA3.1 or pcDNA3.1-circ_0004872. (A) hsa_circ_0004872 expression was evaluated by qRT-PCR. (B) Cell viability was assessed using the CCK8 assay. (C) Flow cytometry analysis determined cell apoptosis. (D) Protein levels of Bax, Bcl-2, Cleaved-caspase3, and Caspase3 were examined by Western blot. Data are presented as mean ± SD from at least three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001

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