Table 3 FACT outcomes at W0, W12 and M6

CogPCI

HE

62.35 ± 12.91

(n = 20)

62.10 ± 9.19

(n = 20)

66.23 ± 8.08

(n = 13)

not significant

MDR

60.78 ± 12.48

(n = 31)

57.16 ± 12.45

(n = 31)

55.00 ± 13.85

(n = 28)

not significant

CogOth

HE

15.50 ± 0.83

15.30 ± 1.59

15.38 ± 0.96

not significant

MDR

15.29 ± 1.42

14.84 ± 2.18

14.70 ± 2.05

not significant

CogPCA

HE

23.05 ± 3.73

21.05 ± 5.28

23.54 ± 3.48

F = 1.487, p = 0.253

MDR

22.81 ± 4.53

20.19 ± 5.28^a

18.38 ± 6.30^a

F = 7.839, p = 0.002*

CogQOL

HE

14.60 ± 2.26

14.75 ± 2.45

14.31 ± 3.25

not significant

MDR

14.06 ± 3.14

13.74 ± 3.53

13.00 ± 3.98

not significant

FACT-Fatigue

HE

40.35 ± 10.45

39.20 ± 11.41

44.31 ± 5.78

not significant

MDR

36.53 ± 10.43

38.63 ± 10.94

39.36 ± 10.30

not significant