Fig. 1
From: FLI1 induces erythroleukemia through opposing effects on UBASH3A and UBASH3B expression
FLI1 regulates UBASH3A and UBASH3B transcription in leukemic cells. A Heatmap of UBASH3A and UBASH3B expression following FLI1 knockdown (shFLI1) versus control leukemia cells. B-D RT-qPCR analysis for expression of FLI1 (B), UBASH3B (C), and UBASH3A (D) in shFLI1 cells versus scrambled control leukemic cells. E Western blot analysis for FLI1, UBASH3A, and UBASH3B compared to the loading control GAPDH in shFLI1 versus scrambled control HEL cells. P < 0.001 (***). Relative density (Rd) determined by densitometer is shown. The full-length blots/gels for Fig. 1E are presented in Supplementary Fig. 9