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Table 2 Clinical characteristics of the training and validation cohorts

From: Contrast-enhanced CT radiomics for preoperative prediction of stage in epithelial ovarian cancer: a multicenter study

Characteristics

Training (n = 106)

P-value

Internal validation (n = 46)

P-value

External validation (n = 49)

P-value

Early-stage

(n = 39)

Advanced- stage (n = 67)

Early-stage

(n = 17)

Advanced-

stage (n = 29)

Early-stage

(n = 21)

Advanced- stage (n = 28)

Age (years)

54.56 ± 7.76

55.76 ± 9.72

0.5131

53.1 ± 13.6

58.31 ± 10.29

0.1461

55.57 ± 7.97

56.07 ± 8.67

0.8371

Menopause

  

0.6902

  

0.2762

  

0.9302

Yes

31 (79.5%)

51 (76.1%)

 

11 (64.7%)

23 (79.3%)

 

14 (66.7%)

19 (67.9%)

 

No

8 (20.5%)

16 (12.9%)

 

6 (35.3%)

6 (20.7%)

 

7 (33.3%)

9 (32.1%)

 

CA125 (U/mL)

236.2

(120.4, 630)

1158

(247, 2973.7)

0.0023

221.6

(88, 622.2)

676

(255,1187.3)

0.0333

224.9

(73.0, 802)

1058

(332.7,1997)

0.0033

CA199 (U/mL)

14.38

(5.75, 38.2)

14.7

(8.9, 27.6)

0.5933

9.33

(4.0, 36.3)

14.58

(8.11, 28.7)

0.9373

13.51

(6.1, 149.9)

9.52

(5.48, 19.3)

0.3323

Tumor location

  

0.0272

  

0.0792

  

< 0.0012

Bilateral

14 (35.9%)

39 (58.2%)

 

6 (35.3%)

18 (62.1%)

 

6 (28.6%)

23 (82.1%)

 

Unilateral

25 (64.1%)

28 (41.8%)

 

11 (64.7%)

11 (37.9%)

 

15 (71.4%)

5 (17.9%)

 
  1. Data are presented as mean ± standard deviation for normally distributed continuous variables, median (interquartile range) for non-normally distributed continuous variables, or number (%) for categorical variables. CA125, carcinoma antigen 125; CA199, Carbohydrate antigen 199. 1t test. 2chi-square test. 3Mann-Whitney U test
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