| Total study population1 (n = 72,913) | Sub-grouped study population with known disease stage (n = 67,025) | ||||
---|---|---|---|---|---|---|
Low-stage subpopulation2 (n = 36,744) | High-stage subpopulation3 (n = 30,281) | |||||
Cases (n = 12,160) | Controls (n = 60,753) | Cases (n = 6,126) | Controls (n = 30,618) | Cases (n = 5,050) | Controls (25,231) | |
Age | Â | Â | Â | Â | ** | ** |
 < 35  35–44  45–54  55–64  65–74  > 75 | 1,996 (16.4%) 2,856 (23.5%) 2,148 (17.7%) 1,842 (15.2%) 1,758 (14.5%) 1,760 (12.8%) | 9,964 (16.4%) 14,288 (23.5%) 10,745 (17.7%) 9,208 (15.2%) 8,774 (14.4%) 7,774 (12.8%) | 1,489 (24.3%) 1,955 (31.9%) 1,136 (18.5%) 733 (12.0%) 542 (8.9%) 271 (4.4%) | 7,433 (24.3%) 9,780 (31.9%) 5,685 (18.6%) 3,667 (12.0%) 2,700 (8.8%) 1,353 (4.4%) | 356 (7.1%) 710 (14.1%) 872 (17.3%) 1,003 (19.9%) 1,056 (20.9%) 1,053 (20.9%) | 1,776 (7.0%) 3,553 (14.1%) 4,362 (17.3%) 5,010 (19.9%) 5,277 (20.9%) 5,253 (20.8%) |
Cohort | Â | Â | Â | Â | ** | ** |
 1987–1992  1993–1998  1999–2004  2005–2010  2011–2016 | 2,974 (24.5%) 2,578 (21.2%) 2,205 (18.1%) 2,206 (18.1%) 2,197 (18.1%) | 14,858 (24.5%) 12,882 (21.2%) 11,012 (18.1%) 11,020 (18.1%) 10,981 (18.1%) | 1,618 (26.4%) 1,253 (20.5%) 1,079 (17.6%) 1,048 (17.1%) 1,128 (18.4%) | 8,088 (26.4%) 6,262 (20.5%) 5,389 (17.6%) 5,239 (17.1%) 5,640 (18.4%) | 1,224 (24.2%) 1,159 (22.9%) 940 (18.6%) 937 (18.6%) 790 (15.6%) | 6,116 (24.2%) 5,791 (22.9%) 4,694 (18.6%) 4,681 (18.6%) 3,949 (15.6%) |
Education | Â | * | Â | * | ** | **, * |
 Short  Medium  High  Unknown | 4,517 (37.2%) 4,010 (32.9%) 2,230 (18.3%) 1,403 (11.5%) | 19,089 (31.4%) 20,911 (34.4%) 13,489 (22.2%) 7,264 (12.0%) | 1,946 (31.8%) 2,350 (38.4%) 1,489 (24.3%) 341 (5.6%) | 8,675 (28.3%) 11.779 (38.5%) 8,121 (26.5%) 2,043 (6.7%) | 2,233 (44.2%) 1.340 (26.5%) 584 (11.6%) 893 7.7%) | 8,881 (35.2%) 7.556 (29.9%) 4,365 (17.3%) 4,429 (17.6%) |
Comorbidity | Â | Â | Â | Â | ** | ** |
 CCI = 0  CCI = 1  CCI = 2  CCI > 2 | 10,265(84.4%) 956 (7.9%) 650 (5.4%) 289 (2.4%) | 51,793(85.3%) 4,601 (7.6%) 3,071 (5.1%) 1,288 (2.1%) | 5,461 (89.1%) 355 (5.8%) 231 (3.8%) 79 (1.3%) | 27,364 (89.4%) 1,718 (5.6%) 1,128 (3.7%) 408 (1.3%) | 4,075 (80.7%) 507 (10.0%) 327 (6.5%) 141 (2.8%) | 20,515 (81.3%) 2,390 (9.5%) 1,615 (6.4%) 711 (2.8%) |
Working status | Â | * | Â | * | ** | **, * |
 Working  Senior  Other  Unknown | 5,867 (48.3%) 4,608 (37.9%) 1,677 (13.8%) 8 (0.1%) | 31,546 (51.9%) 21,361 (35.2%) 7,226 (11.9%) 620 (1.0%) | 3,824 (62.4%) 1,327 (21.7%) 973 (15.9%) (0%) | 19,493 (63.7%) 6,249 (20.4%) 4.533 (14.8%) 343 (1.1%) | 1,648 (32.6%) 2,809 (55.6%) 592 (11.7%) (0%) | 9,912 (39.3%) 12,858 (51.0%) 2,231 (8.8%) 230(1%) |
Socio-economic status | Â | * | Â | * | ** | **, * |
 Low  High  Unknown | 6,555 (53.9%) 3,776 (31.1%) 1,829 (15.0%) | 32,863 (54.1%) 23,338 (38.4%) 4,552 (7.5%) | 3,171 (51.8%) 2,335 (38.1%) 620 (10.1%) | 15,355 (50.2%) 12,665 (41.4%) 2,598 (8.5%) | 2,865 (56.6%) 1,203 (23.8%) 982 (19.5%) | 14,560 (57.7%) 9,070 (36.0%) 1,601 (6.4%) |
Civil status | Â | * | Â | * | ** | **, * |
 Living alone  Living with a partner  Unknown | 4,613 (37.9%) 7,482 (61.5%) 65 (0.5%) | 18,984 (31.3%) 40.993 (67.5%) 776 (1.3%) | 1,919 (31.3%) 4,179 (68.2%) 28 (0.5%) | 7,954 (26.0%) 22,210 (72.5%) 454 (1.5%) | 2,256 (44.7%) 2,768 (54.8%) 30 (0.5%) | 9,217 (36.5%) 15,751 (62.4%) 263 (1.0%) |
Born in Denmark | Â | * | Â | * | Â | ** |
 Yes  No | 11,132 (91.6%) 1,028 (8.5%) | 54,752 (90.1%) 6,001 (9.9%) | 5,601 (91.4%) 525 (8.6%) | 27,246 (89.0%) 3,372 (11.0%) | 4,629 (91.7%) 421 (8.3%) | 23,050 (91.4%) 2,181 (8.6%) |