Table 2 Clinicopathological variables and correlation with PPARG expression in the matched case control study population of 246 CRC patients. The percentages are shown in parentheses
Characteristics | Total | PPARG | P-Value | |
|---|---|---|---|---|
low | high | |||
All patients | 246 (100) | 122 (49.6) | 124 (50.4) | – |
Age | ||||
≤ 66 | 122 (49.6) | 60 (49.2) | 62 (50.0) | 0.898 |
> 66 | 124 (50.4) | 62 (50.8) | 62 (50.0) | |
Sex | ||||
male | 145 (58.9) | 61 (50) | 84 (67.7) | 0.005 |
female | 101 (41.1) | 61 (50) | 40 (32.3) | |
Tumour location | ||||
Colon | 108 (43.9) | 49 (40.2) | 59 (47.6) | 0.275 |
Rectosigmoid | 22 (8.9) | 14 (11.5) | 8 (6.5) | |
Rectum | 116 (47.2) | 59 (48.4) | 57 (46.0) | |
pT-Stage | ||||
T0 | 2 (0.8) | 0 (0) | 2 (1.6) | |
T1 | 11 (4.5) | 6 (4.9) | 5 (4.1) | |
T2 | 30 (12.2) | 11 (9.0) | 19 (15.3) | 0.343 |
T3 | 175 (71.1) | 91 (74.6) | 84 (67.7) | |
T4 | 28 (11.4) | 14 (11.5) | 14 (11.3) | |
Tumour grade | ||||
Low grade | 166 (67.8) | 83 (68.0) | 83 (67.5) | 0.926 |
High grade | 79 (32.2) | 39 (32.0) | 40 (32.5) | |
N-Stage | ||||
N negative | 115 (46.7) | 60 (49.2) | 55 (44.4) | 0.441 |
N positive | 125 (50.8) | 59 (48.4) | 66 (53.2) | |
Unknown | 6 (2.4) | 3 (2.5) | 3 (2.4) | |
M-status | ||||
M0 | 82 (33.3) | 47 (38.5) | 35 (28.2) | Global: 0.053 |
HEP | 82 (33.3) | 43 (35.2) | 39 (31.5) | M0 vs. HEP: 0.53 |
PUL | 82 (33.3) | 32 (26.2) | 50 (40.3) | M0 vs. PUL: 0.019 |
Diabetes Mellitus II | ||||
No | 191 (77.6) | 96 (78.7) | 95 (76.6) | 0.249 |
Yes | 33 (13.4) | 13 (10,7) | 20 (16.1) | |
Unknown | 22 (8.9) | 13 (10.7) | 9 (7.3) | |