Fig. 6

miR-1270 targets PKM2 directly A Starbase database displayed the supposing binding regions of miR-1270 in the seed region of 3'UTR of PKM2. B The SW480 cells were performed transfection with a luciferase reporter vector and the miR-1270 mimics for 48 h, following measurement of the luciferase signals. C The SW480 cells were transfected for 48 h with 50 pmol/mL miR-1270 mimics and relative negative controls, then the PKM2 expression was evaluated via qRT-PCR. D PKM2 level was detected in the tumor and in the normal tissues by qRT-PCR. *P < 0.05, **P < 0.01, ***P < 0.001, vs. Control group.