Fig. 5

MiR-1270 overexpression suppresses the malignancy and glucose metabolism of colorectal tumor cells. The SW480 cells were transfected with miR-1270 mimics at the concentration of 50 pmol/mL and the relative negative controls for 48 h. A CCK-8 assay was performed to assess the cell viability and proliferation of SW480 cells. B SW480 cell's invasion ability was revealed through transwell assay. C-E The ATP production, lactate secretion, and glucose uptake of SW480 were verified by indicated commercialized assay. *P < 0.05, **P < 0.01, ***P < 0.001, vs. Control group.