Fig. 2

TMPO-AS1 RNA interference restrains the malignant characteristics of colorectal tumor cells. The SW480 cells were performed with 48 h of transfection of 40 pmol/mL TMPO-AS1 siRNAs and relative negative controls. A Cell viability and proliferation of SW480 cells in the indicated groups. B Flow cytometry assay was implemented to determine the SW480 cells' apoptosis. C Cell migration viability after transfection was assessed through wound-healing assay. D SW480 cell's invasion ability was revealed through transwell assay. E Levels of PCNA, Ki67, MMP2, and MMP9, and internal control β-actin was measured though western blot. *P < 0.05, **P < 0.01, ***P < 0.001, vs. Control group.