Trajectories of neutrophil-to-lymphocyte ratios during neoadjuvant chemotherapy correlate with short- and long-term outcomes in gastric cancer: a group-based trajectory analysis

Table 3 Hazard ratios (HRs) for tumor recurrence in the trajectory groups

	Unadjusted model		Preliminary adjusted model^a		Fully adjusted model^b
RFS	Hazard Ratio (95% CI)	p value	Hazard Ratio (95% CI)	p value	Hazard Ratio (95% CI)	p value
Stable	Reference		Reference		Reference
Ascent-descend	1.905 (1.185–3.060)	0.008	1.970 (1.221–3.178)	0.005	1.989 (1.157–3.419)	0.013
Continuous descent	2.400 (1.426–4.039)	0.001	2.322 (1.363–3.985)	0.002	2.031 (1.098–3.757)	0.024

Note ^a Adjusted for age, gender, BMI, ECOG scoring scale
^b Additional adjusted for CT TNM stage, Clinical response per RECIST criteria, Tumor location, Resection range, Multiorgan resection (yes/no), Intraoperative blood loss, number of lymph node dissections, Lymphovascular invasion (yes/no), Neural infiltration (yes/no), Tumor regression grade, ypTNM stage

ISSN: 1471-2407