Fig. 4

Characterization of the genetic alterations in the LDHs families. A General profile of genetic alterations in LDHs families from the pan-cancer dataset in the cBioportal database; B Frequency of LDHA alterations from the cBioportal database, dot plots showing the correlation between LDHA copy number and mRNA expression in cBioportal and the number of LDHA mutations in the pan-cancer dataset; C Alteration frequency of LDHB from the cBioportal database, dot plots showing the correlation between copy number and mRNA expression of LDHB from cBioportal and the number of LDHB mutations in pan-cancer; D From the cBioportal database, the dot plot shows the correlation between copy number and mRNA expression of LDHC from cBioportal and the number of mutations in LDHC in pan-cancer; E The frequency of LDHD alterations from the cBioportal database, the dot plot shows the correlation between LDHD copy number and mRNA expression in cBioportal and the number of LDHD mutations in pan-cancer