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Fig. 11 | BMC Cancer

Fig. 11

From: Systematic analysis of the role of LDHs subtype in pan-cancer demonstrates the importance of LDHD in the prognosis of hepatocellular carcinoma patients

Fig. 11

Knockdown or overexpression of LDHD affects HCC cell migration and invasion. A Wound healing assay was used to investigate the effects of LDHD siRNA and GFP-LDHD on HepG2 and Huh7 cell migration; B Transwell assay was used to determine the effects of LDHD siRNA and GFP-LDHD on HepG2 and Huh7 cell migration and invasion; C Western Blotting was performed to measure the expression levels of N-cadherin, E-cadherin, MMP-2, MMP-9 and Akt phosphorylation after LDHD siRNA and GFP-LDHD transfection in HepG2 and Huh7 cell lines. *P < 0.05, **P < 0.01, ***P < 0.001 vs. NC group

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BMC Cancer

ISSN: 1471-2407

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