Fig. 7From: Integrated transcriptomics uncovers an enhanced association between the prion protein gene expression and vesicle dynamics signatures in glioblastomasSchematic diagram of the mechanisms involved in extra- and intracellular trafficking by which PrPC may affect GBM biology. PrPC is transiently found in the ER and Golgi during its biogenesis and is internalized by a vesicle-mediated process to be recycled or degraded. Vesicular biogenesis, endocytic path and exocytosis are processes enriched in GBM cells with high PRNP expressionBack to article page