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Fig. 5 | BMC Cancer

Fig. 5

From: Integrated transcriptomics uncovers an enhanced association between the prion protein gene expression and vesicle dynamics signatures in glioblastomas

Fig. 5

Impact of PRNP and vesicle dynamics signatures on patients’ overall survival. A Kaplan-Meier curves demonstrate the overall survival of GBM patients either below or above the optimal cutoff, calculated for PRNP expression levels. A risk table is shown at the left. Statistical significance was assessed using a log-rank test, and p-value is stated in the graph. B Kaplan-Meier curves demonstrate the overall survival of GBM patients either below or above the optimal cutoff, calculated for gene signatures of traffic- or vesicle-related processes (GO). Statistical significance was assessed using log-rank tests, and p-values are stated in the graphs. Inserts show PRNP normalized expression in samples above and under the cutoff of each gene signature

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