Fig. 2

SR-A498 cell biological function in the presence/absence of sunitinib. The proliferation ability of SR-A498 cells was determined by CCK-8 assay (A). The figure only marks the significance of 96 h drug treatment. The apoptosis of A498 cells and SR-A498 cells was determined by flow cytometry (B). The migration ability of A498 cells and SR-A498 cells was determined by cell scratch experiments. (C). The migration (D) and invasion (E) abilities of A498 cells and SR-A498 cells were determined by Transwell assays. All representative images and statistical analyses are shown above. All experiments were repeated in triplicate in three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001