Skip to main content
Fig. 2 | BMC Cancer

Fig. 2

From: Hypoxia-induced miR-181a-5p up-regulation reduces epirubicin sensitivity in breast cancer cells through inhibiting EPDR1/TRPC1 to activate PI3K/AKT signaling pathway

Fig. 2

Overexpression of EPDR1 inhibits malignant progression of BC. The MCF-7 cells stably overexpressing EPDR1. (A) The expression of EPDR1 mRNA was examined by RT-qPCR. (B) The expression of EPDR1 protein was examined by western blot assay. (C) The proliferation of cells was examined by CCK-8 assay. (D) The migration and invasion of cells was examined by Transwell assay. (E) The expression of EMT-related protein was examined by western blot assay. (F) Tumor volume and weight. (G) Tumor metastasis was observed by bioluminescence imaging, lung tissue gross observation, and HE staining. *, vs. ov-NC group, p < 0.05

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us