Fig. 6

High expression of TAZ inhibits mitophagy in KIRC cells. (A) TAZ expression and quantification in different kidney cells (HK2, A498, 786-O); (B) Western Blot validate siRNA knockdown of TAZ; (C) JC-1 was used to detect the effect of different expression of TAZ on mitochondrial membrane potential; (D) Determination of the effect of different expression of TAZ on ATP content; (E) Determination of the effect of different expression of TAZ on ADP/ATP ratio; (F) CCK8 assay was used to detect the effect of TAZ knockdown on cell viability