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Table 4 Factors associated with pathological complete response (PCR) by univariate and multivariate logistic regression analysis

From: Impact of chronic obstructive pulmonary disease on the efficacy and safety of neoadjuvant immune checkpoint inhibitors combined with chemotherapy for resectable non-small cell lung cancer: a retrospective cohort study

 

Univariate analysis

Multivariate analysis

OR

95% CI

P-value

OR

95% CI

P-value

Presence of COPD

2.974

1.063–8.318

0.038

3.020

1.042–8.757

0.042

Age(> 65 vs. ≤ 65)

1.333

0.487 -3.654

0.576

   

Sex(male vs. female)

1.556

0.297 -8.160

0.601

   

SI, pack-years (> 20 vs. ≤ 20)

1.571

0.549 -4.501

0.400

1.328

0.440–4.002

0.615

ECOG PS score (1 vs. 0)

1.500

0.538–4.183

0.438

   

Histology(Non-SCC vs. SCC)

0.754

0.183–3.102

0.696

0.897

0.195–4.135

0.889

cTNM Stagea

1.339

0.465 -3.854

0.588

1.445

0.441–7.731

0.543

Neoadjuvant cycle(> 2 vs. ≤ 2)

1.230

0.450–3.362

0.686

1.222

0.405–3.689

0.722

  1. Abbreviations: SI Smoking index, OR Odds ratio
  2. aStage IA + IIA + IIB vs. IIIA + IIIB