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Table 4 Factors associated with currently smoking, physical inactivity and binge drinking among childhood cancer survivors

From: Health-related risk behaviors among U.S. childhood cancer survivors: a nationwide estimate

Characteristics

Currently smoking

Physical inactivity

Binge drinking

Univariate

Multivariable

Univariate

Multivariable

Univariate

Multivariable

Odds Ratio

(95% CI)

p-value

Odds Ratio

(95% CI)

p-value

Odds Ratio

(95% CI)

p-value

Odds Ratio

(95% CI)

p-value

Odds Ratio

(95% CI)

p-value

Odds Ratio

(95% CI)

p-value

Demographic and socioeconomic factors

Age at survey (years)

  18–39

Ref

 < 0.001

***

Ref

0.008

**

Ref

0.508

Ref

0.165

Ref

 < 0.001

***

Ref

0.003

**

  40–64

0.71 (0.43, 1.18)

0.61 (0.31, 1.19)

1.36 (0.79, 2.34)

1.77 (0.96, 3.26)

0.36 (0.20, 0.65)

0.42 (0.21, 0.85)

  65 and older

0.19 (0.09, 0.43)

0.17 (0.06, 0.52)

1.06 (0.56, 2.00)

1.16 (0.54, 2.46)

0.11 (0.04, 0.33)

0.15 (0.05, 0.52)

Sex (Ref. to Male)

  Female

1.90 (1.15, 3.13)

0.012

*

1.19 (0.61, 2.29)

0.612

0.90 (0.55, 1.47)

0.671

0.65 (0.37, 1.16)

0.146

0.41 (0.24, 0.70)

0.001

**

0.30 (0.16, 0.57)

 < 0.001

***

Region

  Northeast

Ref

0.692

Ref

0.937

Ref

0.007

**

Ref

0.108

Ref

0.929

Ref

0.947

  Midwest

1.18 (0.59, 2.37)

0.80 (0.32, 1.99)

2.15 (0.99, 4.63)

1.82 (0.78, 4.21)

1.19 (0.53, 2.66)

0.95 (0.38, 2.35)

  South

1.33 (0.68, 2.60)

1.04 (0.43, 2.52)

2.97 (1.42, 6.20)

2.27 (1.03, 5.03)

1.29 (0.59, 2.79)

1.13 (0.47, 2.74)

  West

0.94 (0.49, 1.79)

0.98 (0.43, 2.21)

1.20 (0.57, 2.54)

1.11 (0.50, 2.47)

1.10 (0.53, 2.30)

0.89 (0.38, 2.08)

Race

  White only, Non-Hispanic

Ref

0.113

Ref

0.734

Ref

0.209

Ref

0.232

Ref

0.115

Ref

0.479

  Black only, Non-Hispanic

1.23 (0.38, 4.04)

0.58 (0.12, 2.77)

1.71 (0.56, 5.26)

1.31 (0.37, 4.63)

1.36 (0.37, 5.06)

0.92 (0.20, 4.33)

  Others

1.93 (1.04, 3.57)

1.13 (0.52, 2.47)

0.56 (0.25, 1.24)

0.48 (0.20, 1.16)

2.03 (1.04, 3.97)

1.60 (0.74, 3.45)

Education Level

  High school and below

Ref

 < .001

***

Ref

0.002

**

Ref

0.003

**

Ref

0.242

Ref

0.002

**

Ref

0.056

  Attended college or technical School

0.45 (0.25, 0.78)

0.42 (0.20, 0.86)

0.96 (0.54, 1.71)

1.04 (0.54, 2.00)

0.65 (0.35, 1.22)

0.81 (0.39, 1.65)

  College or technical school and above

0.15 (0.08, 0.27)

0.25 (0.12, 0.54)

0.39 (0.21, 0.71)

0.60 (0.29, 1.22)

0.31 (0.16, 0.59)

0.41 (0.19, 0.86)

Employment

  Employed/self-employed

Ref

 < 0.001

***

NA

Ref

0.010

*

NA

Ref

0.021

*

NA

  Out of work/A homemaker/A student

1.55 (0.83, 2.90)

1.13 (0.56, 2.28)

1.14 (0.57, 2.26)

  Retired

0.22 (0.09, 0.58)

1.05 (0.54, 2.03)

0.16 (0.05, 0.52)

  Unable to work

3.56 (1.79, 7.07)

3.22 (1.60, 6.48)

0.84 (0.36, 1.94)

Marital status

  Married/A member of an unmarried couple

Ref

0.009

**

Ref

0.385

Ref

0.278

NA

Ref

0.029

*

Ref

0.175

  Divorced/widowed/separated

2.29 (1.33, 3.94)

1.57 (0.73, 3.40)

1.52 (0.88, 2.64)

0.50 (0.24, 1.04)

0.45 (0.19, 1.05)

  Never married

1.71 (0.95, 3.08)

0.86 (0.38, 1.93)

1.00 (0.53, 1.87)

1.48 (0.81, 2.71)

0.79 (0.38, 1.65)

Number of Children in household: (Ref. to No children)

  One or more

2.60 (1.62, 4.17)

 < 0.001

***

2.30 (1.22, 4.31)

0.010

*

0.81 (0.49, 1.36)

0.434

NA

1.63 (0.96, 2.79)

0.071

0.97 (0.52, 1.81)

0.916

Any healthcare coverage (Ref. to No)

  Yes

0.37 (0.18, 0.75)

0.006

**

0.72 (0.28, 1.88)

0.506

0.85 (0.38, 1.89)

0.686

NA

0.51 (0.23, 1.12)

0.092

0.82 (0.32, 2.09)

0.681

Annual household income

  Less than $15,000

Ref

 < 0.001

***

Ref

0.062

Ref

0.002

**

Ref

0.032

*

Ref

0.556

NA

  $15,000 to less than $25,000

0.38 (0.17, 0.88)

0.50 (0.18, 1.41)

0.80 (0.33, 1.92)

1.19 (0.45, 3.12)

0.43 (0.15, 1.29)

  $25,000 to less than $35,000

0.21 (0.08, 0.55)

0.35 (0.10, 1.18)

1.60 (0.65, 3.95)

2.80 (0.98, 8.01)

0.62 (0.20, 1.87)

  $35,000 to less than $50,000

0.15 (0.06, 0.38)

0.23 (0.07, 0.76)

0.69 (0.27, 1.73)

1.39 (0.48, 4.05)

0.94 (0.35, 2.50)

  $50,000 or more

0.10 (0.05, 0.21)

0.22 (0.08, 0.65)

0.38 (0.19, 0.79)

0.73 (0.29, 1.80)

0.68 (0.32, 1.47)

Clinical factors

Days with poor mental health in past 30 days (Ref. to zero day)

  At least 1 day

3.38 (2.00, 5.70)

 < 0.001

***

1.64 (0.84, 3.21)

0.148

1.46 (0.89, 2.39)

0.135

1.27 (0.70, 2.29)

0.437

1.96 (1.12, 3.44)

0.018

*

1.75 (0.89, 3.44)

0.106

Days with poor physical health in past 30 days (Ref. to zero day)

  At least 1 day

2.56 (1.59, 4.11)

 < 0.001

***

1.00 (0.51, 1.94)

0.999

2.78 (1.69, 4.58)

 < 0.001

***

2.33 (1.28, 4.22)

0.006

**

1.11 (0.66, 1.88)

0.694

NA

Obesity (Ref. to No)

  Yes

0.81 (0.51, 1.30)

0.390

NA

1.33 (0.80, 2.22)

0.266

NA

1.31 (0.75, 2.28)

0.346

NA

Number of chronic health conditions (Ref. to none or 1)

  > 1

4.27 (2.58, 7.07)

 < .001

***

3.52 (1.76, 7.02)

 < 0.001

***

1.84 (1.13, 2.98)

0.014

*

1.15 (0.63, 2.12)

0.645

1.55 (0.92, 2.63)

0.101

2.13 (1.11, 4.08)

0.023

*

Length of follow-up (years)

  0–24

Ref

0.005

**

HC

Ref

0.947

NA

Ref

 < .001

***

NA

  25–49

0.71 (0.43, 1.17)

1.08 (0.62, 1.86)

0.44 (0.25, 0.78)

  50 + 

0.22 (0.10, 0.47)

1.10 (0.59, 2.05)

0.12 (0.04, 0.34)

  1. HC, highly correlated with one of the covariates included in the multivariable models, NA, not applicable covariate for not satisfying the variable selection criterium in the model fitting step
  2. *p < 0.05, **p < 0.01, ***p < 0.001